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Puppy Nutrition
The developmental life stage of dogs requires a specific intake of nutrients to ensure proper growth and development and to meet energy requirements. Despite the fact that puppies have different nutritional requirements compared to their adult counterparts, of the 652 breeders surveyed in the United States and Canada in 2012, 8.7% report feeding puppies commercial diets not intended for the developmental life stage of canines. Large and small dog breeds have even more specific nutrient requirements during growth, such as adjusted calcium to phosphorus ratio, and as such should receive a breed specific growth formula. Feeding diets formulated by a nutritionist for specific breeds and life stage differences in nutrient requirements ensures a growing puppy will receive the proper nutrition associated with appropriate skeletal, neurological and immune development. This includes nutrients such as protein, fibre, essential fatty acids, calcium and vitamin E. It is therefore important to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Memory T Cell
Memory T cells are a subset of T lymphocytes that might have some of the same functions as memory B cells. Their lineage is unclear. Function Antigen-specific memory T cells specific to viruses or other microbial molecules can be found in both central memory T cells (TCM) and effector memory T cells (TEM) subsets. Although most information is currently based on observations in the cytotoxic T cells (CD8-positive) subset, similar populations appear to exist for both the helper T cells ( CD4-positive) and the cytotoxic T cells. Primary function of memory cells is augmented immune response after reactivation of those cells by reintroduction of relevant pathogen into the body. It is important to note that this field is intensively studied and some information may not be available as of yet. * Central memory T cells (TCM): TCM lymphocytes have several attributes in common with stem cells, the most important being the ability of self-renewal, mainly because of high level of phosphoryl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypothyroidism In Dogs
Hypothyroidism is an endocrine disorder in which the thyroid gland fails to produce sufficient thyroid hormones. Hypothyroidism is one of the most common endocrinopathies in dogs. It is either acquired or congenital. Classification Hypothyroidism is classified as either primary, secondary, or tertiary. Primary hypothyroidism is for when the cause is due to an abnormality of the thyroid gland, secondary hypothyroidism is when the cause is decreased thyroid-stimulating hormone levels, and tertiary hypothyroidism is when the cause is an inadequate amount of thyrotropin-releasing hormone being released. Causes The causes of primary hypothyroidism include: *Lymphocytic thyroiditis *Idiopathic atrophy *Neoplasia destroying the thyroid gland *Iodine deficiency *Ingestion of goitrogen *Iatrogenic *Leishmaniasis *Congenital hypothyroidism Lymphocytic thyroiditis and idiopathic atrophy are the most common causes of primary hypothyroidism. The causes of secondary hypothyroidism include: *Pi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urea
Urea, also known as carbamide, is an organic compound with chemical formula . This amide has two amino groups (–) joined by a carbonyl functional group (–C(=O)–). It is thus the simplest amide of carbamic acid. Urea serves an important role in the metabolism of nitrogen-containing compounds by animals and is the main nitrogen-containing substance in the urine of mammals. It is a colorless, odorless solid, highly soluble in water, and practically non-toxic ( is 15 g/kg for rats). Dissolved in water, it is neither acidic nor alkaline. The body uses it in many processes, most notably nitrogen excretion. The liver forms it by combining two ammonia molecules () with a carbon dioxide () molecule in the urea cycle. Urea is widely used in fertilizers as a source of nitrogen (N) and is an important raw material for the chemical industry. In 1828 Friedrich Wöhler discovered that urea can be produced from inorganic starting materials, which was an important conceptual milestone ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha amino acids appear in the genetic code. Amino acids can be classified according to the locations of the core structural functional groups, as Alpha and beta carbon, alpha- , beta- , gamma- or delta- amino acids; other categories relate to Chemical polarity, polarity, ionization, and side chain group type (aliphatic, Open-chain compound, acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bifidobacterium
''Bifidobacterium'' is a genus of gram-positive, nonmotile, often branched anaerobic bacteria. They are ubiquitous inhabitants of the gastrointestinal tract though strains have been isolated from the vagina and mouth ('' B. dentium'') of mammals, including humans. Bifidobacteria are one of the major genera of bacteria that make up the gastrointestinal tract microbiota in mammals. Some bifidobacteria are used as probiotics. Before the 1960s, ''Bifidobacterium'' species were collectively referred to as ''Lactobacillus bifidus''. History In 1899, Henri Tissier, a French pediatrician at the Pasteur Institute in Paris, isolated a bacterium characterised by a Y-shaped morphology ("bifid") in the intestinal microbiota of breast-fed infants and named it "bifidus". In 1907, Élie Metchnikoff, deputy director at the Pasteur Institute, propounded the theory that lactic acid bacteria are beneficial to human health. Metchnikoff observed that the longevity of Bulgarians was the result of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mannan Oligosaccharide-based Nutritional Supplements
Mannans are polymers containing the sugar mannose as a principal component. They are a type of polysaccharide comprise hemicellulose, a major source of biomass found in higher plants such as softwoods. These polymers also typically contain two other sugars, galactose and glucose. They are often branched (unlike cellulose). Structural diversity Plant mannans have β(1-4) linkages, occasionally with α(1-6) galactose branches, forming galactomannans. They are insoluble and a form of storage polysaccharide. Ivory nut is a source of mannans. An additional type is galactoglucomannan found in soft wood with a mixed mannose/glucose β(1-4) backbone. Many mannans are acetylated and some from marine sources, have sulfate esters side chains. Yeast and some plants such as conjac and salep have a different type of mannans in their cell wall, with a α(1-6) linked backbone and α(1-2) and α(1-3) linked glucose branches, hence "glucomannan". It is water soluble. It is serologically simi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fructooligosaccharide
Fructooligosaccharides (FOS) also sometimes called oligofructose or oligofructan, are oligosaccharide fructans, used as an alternative sweetener. FOS exhibits sweetness levels between 30 and 50 percent of sugar in commercially prepared syrups. It occurs naturally, and its commercial use emerged in the 1980s in response to consumer demand for healthier and calorie-reduced foods. Chemistry Two different classes of fructooligosaccharide (FOS) mixtures are produced commercially, based on inulin degradation or transfructosylation processes. FOS can be produced by degradation of inulin, or polyfructose, a polymer of D-fructose residues linked by β(2→1) bonds with a terminal α(1→2) linked D-glucose. The degree of polymerization of inulin ranges from 10 to 60. Inulin can be degraded enzymatically or chemically to a mixture of oligosaccharides with the general structure Glu–Frun (abbrev. GFn) and Frum (Fm), with n and m ranging from 1 to 7. This process also occurs to some extent i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Short-chain Fatty Acid
Short-chain fatty acids (SCFAs) are fatty acids with fewer than six carbon atoms. Derived from intestinal microbial fermentation of indigestible foods, SCFAs are the main energy source of colonocytes, making them crucial to gastrointestinal health. SCFAs all possess varying degrees of water solubility, which distinguishes them from longer chain fatty acids that are immiscible. List of SCFAs Functions SCFAs are produced when dietary fiber is fermented in the colon. Macronutrient composition (carbohydrate, protein, or fat) of diets affects circulating SCFAs. Acetate, propionate, and butyrate are the three most common SCFAs. SCFAs and medium-chain fatty acids are primarily absorbed through the portal vein during lipid digestion, while long-chain fatty acids are packed into chylomicrons, enter lymphatic capillaries, then transfer to the blood at the subclavian vein. SCFAs have diverse physiological roles in body functions. They can affect the production of lipids, energy and vit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dietary Fiber
Dietary fiber (in British English fibre) or roughage is the portion of plant-derived food that cannot be completely broken down by human digestive enzymes. Dietary fibers are diverse in chemical composition, and can be grouped generally by their solubility, viscosity, and fermentability, which affect how fibers are processed in the body. Dietary fiber has two main components: soluble fiber and insoluble fiber, which are components of plant-based foods, such as legumes, whole grains and cereals, vegetables, fruits, and nuts or seeds. A diet high in regular fiber consumption is generally associated with supporting health and lowering the risk of several diseases. Dietary fiber consists of non- starch polysaccharides and other plant components such as cellulose, resistant starch, resistant dextrins, inulin, lignins, chitins (in fungi), pectins, beta-glucans, and oligosaccharides. Food sources of dietary fiber have traditionally been divided according to whether they provide s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbiota
Microbiota are the range of microorganisms that may be commensal, symbiotic, or pathogenic found in and on all multicellular organisms, including plants. Microbiota include bacteria, archaea, protists, fungi, and viruses, and have been found to be crucial for immunologic, hormonal, and metabolic homeostasis of their host. The term ''microbiome'' describes either the collective genomes of the microbes that reside in an ecological niche or within the microbes themselves. The microbiome and host emerged during evolution as a synergistic unit from epigenetics and genetic characteristics, sometimes collectively referred to as a holobiont. The presence of microbiota in human and other metazoan guts has been critical for understanding the co-evolution between metazoans and bacteria. Microbiota play key roles in the intestinal immune and metabolic responses via their fermentation product (short-chain fatty acid), acetate. Introduction All plants and animals, from simple life fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
