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Psilocybe Cyanescens
''Psilocybe cyanescens'' (sometimes referred to as wavy caps or as the potent Psilocybe) is a species of potent psychedelic mushroom. The main compounds responsible for its psychedelic effects are psilocybin and psilocin. It belongs to the family Hymenogastraceae. A formal description of the species was published by Elsie Wakefield in 1946 in the Transactions of the British Mycological Society, based on a specimen she had recently collected at Kew Gardens. She had begun collecting the species as early as 1910. The mushroom is not generally regarded as being physically dangerous to adults. Since all the psychoactive compounds in ''P. cyanescens'' are Aqueous solution, water-soluble, the fruiting bodies can be rendered non-psychoactive through parboiling, allowing their culinary use. However, since most people find them overly bitter and they are too small to have great nutritive value, this is not frequently done. ''Psilocybe cyanescens'' can sometimes fruit in colossal quanti ...
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Elsie Maud Wakefield
Elsie Maud Wakefield, OBE (3 July 1886 – 17 June 1972) was an English mycologist and plant pathologist. Background and education She was born in Birmingham, the daughter of a science teacher. She was educated at Swansea High School for Girls and then went to Somerville College, Oxford, where she received a first class honours degree in botany. Career in mycology After completing her degree, Wakefield was awarded a Gilchrist scholarship and worked with Prof. Karl von Tubeuf in Munich, where she undertook cultural studies on the larger fungi, publishing her first paper there, in German. On her return in 1910, she became assistant to George Massee, head of mycology and cryptogams at the Royal Botanic Gardens, Kew. On his retirement in 1915, she took over his position as head of mycology. In 1920, she took advantage of a travelling scholarship from Somerville College to spend six months working as a mycologist in the West Indies. Subsequently, she remained at Kew until her ...
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Primordia
A primordium (; plural: primordia; synonym: anlage) in embryology, is an organ or tissue in its earliest recognizable stage of development. Cells of the primordium are called primordial cells. A primordium is the simplest set of cells capable of triggering growth of the would-be organ and the initial foundation from which an organ is able to grow. In flowering plants, a floral primordium gives rise to a flower. Although it is a frequently used term in plant biology, the word is used in describing the biology of all multicellular organisms (for example: a tooth primordium in animals, a leaf primordium in plants or a sporophore primordium in fungi.) Primordium development in plants Plants produce both leaf and flower primordia cells at the shoot apical meristem (SAM). Primordium development in plants is critical to the proper positioning and development of plant organs and cells. The process of primordium development is intricately regulated by a set of genes that affect the po ...
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Baeocystin
Baeocystin is a zwitterionic alkaloid and analog of psilocybin. It is found as a minor compound in most psilocybin mushrooms together with psilocybin, norbaeocystin, aeruginascin, and psilocin. Baeocystin is an ''N''-demethylated derivative of psilocybin, and a phosphorylated derivative of 4-HO-NMT (4-hydroxy- ''N''-methyltryptamine). The structures at right illustrate baeocystin in its zwitterionic form. Baeocystin was first isolated from the mushroom '' Psilocybe baeocystis'', and later from '' P. semilanceata'', '' Panaeolus renenosus'', '' Panaeolus subbalteatus'', and '' Copelandia chlorocystis''. It was first synthesized by Troxler ''et al''. in 1959. Little information exists with regard to human pharmacology, but in the book ''Magic Mushrooms Around the World'', author Jochen Gartz reports being aware of a study in which "10 mg of baeocystin were found to be about as psychoactive as a similar amount of psilocybin." Gartz also reported in a research paper that a s ...
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Indole Alkaloids
Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids. Containing more than 4100 known different compounds, it is one of the largest classes of alkaloids. Many of them possess significant physiological activity and some of them are used in medicine. The amino acid tryptophan is the biochemical precursor of indole alkaloids. History The action of some indole alkaloids has been known for ages. Aztecs used the psilocybin mushrooms which contain alkaloids psilocybin and psilocin. The flowering plant ''Rauvolfia serpentina'' which contains reserpine was a common medicine in India around 1000 BC. Africans used the roots of the perennial rainforest shrub Iboga, which contain ibogaine, as a stimulant. An infusion of Calabar bean seeds was given to people accused of crime in Nigeria: its rejection by stomach was regarded as a sign of innoc ...
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Central Europe
Central Europe is an area of Europe between Western Europe and Eastern Europe, based on a common historical, social and cultural identity. The Thirty Years' War (1618–1648) between Catholicism and Protestantism significantly shaped the area's history. The concept of "Central Europe" appeared in the 19th century. Central Europe comprised most of the territories of the Holy Roman Empire and those of the two neighboring kingdoms of Poland and Hungary. Hungary and parts of Poland were later part of the Habsburg monarchy, which also significantly shaped the history of Central Europe. Unlike their Western European (Portugal, Spain et al.) and Eastern European (Russia) counterparts, the Central European nations never had any notable colonies (either overseas or adjacent) due to their inland location and other factors. It has often been argued that one of the contributing causes of both World War I and World War II was Germany's lack of original overseas colonies. After Wor ...
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Western Europe
Western Europe is the western region of Europe. The region's countries and territories vary depending on context. The concept of "the West" appeared in Europe in juxtaposition to "the East" and originally applied to the ancient Mediterranean world, the Roman Empire (Western Roman Empire and Eastern Roman Empire), and medieval " Christendom" (Western Christianity and Eastern Christianity). Beginning with the Renaissance and the Age of Discovery, roughly from the 15th century, the concept of ''Europe'' as "the West" slowly became distinguished from and eventually replaced the dominant use of "Christendom" as the preferred endonym within the region. By the Age of Enlightenment and the Industrial Revolution, the concepts of " Eastern Europe" and "Western Europe" were more regularly used. Historical divisions Classical antiquity and medieval origins Prior to the Roman conquest, a large part of Western Europe had adopted the newly developed La Tène culture. As the Roman ...
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San Francisco Bay Area
The San Francisco Bay Area, often referred to as simply the Bay Area, is a populous region surrounding the San Francisco, San Pablo, and Suisun Bay estuaries in Northern California. The Bay Area is defined by the Association of Bay Area Governments to include the nine counties that border the aforementioned estuaries: Alameda, Contra Costa, Marin, Napa, San Mateo, Santa Clara, Solano, Sonoma, and San Francisco. Other definitions may be either smaller or larger, and may include neighboring counties that do not border the bay such as Santa Cruz and San Benito (more often included in the Central Coast regions); or San Joaquin, Merced, and Stanislaus (more often included in the Central Valley). The core cities of the Bay Area are San Francisco, San Jose, and Oakland. Home to approximately 7.76 million people, Northern California's nine-county Bay Area contains many cities, towns, airports, and associated regional, state, and national parks, connected by a comp ...
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Pacific Northwest
The Pacific Northwest (sometimes Cascadia, or simply abbreviated as PNW) is a geographic region in western North America bounded by its coastal waters of the Pacific Ocean to the west and, loosely, by the Rocky Mountains to the east. Though no official boundary exists, the most common conception includes the U.S. states of Oregon, Washington, and Idaho, and the Canadian province of British Columbia. Some broader conceptions reach north into Alaska and Yukon, south into northern California, and east into western Montana. Other conceptions may be limited to the coastal areas west of the Cascade and Coast mountains. The variety of definitions can be attributed to partially overlapping commonalities of the region's history, culture, geography, society, ecosystems, and other factors. The Northwest Coast is the coastal region of the Pacific Northwest, and the Northwest Plateau (also commonly known as " the Interior" in British Columbia and the Inland Northwest in the U ...
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Psilocybe Cyanescens Range-map
''Psilocybe'' ( ) is a genus of gilled mushrooms, growing worldwide, in the family Hymenogastraceae. Most or nearly all species contain the psychedelic compounds psilocybin and psilocin. Taxonomy Taxonomic history A 2002 study of the molecular phylogeny of the agarics indicated that the genus ''Psilocybe'' as then defined was polyphyletic, falling into two distinct clades that are not directly related to each other. The blue-staining hallucinogenic species constituted one clade and the non-bluing species the other. The previous type species of the genus, ''Psilocybe '' (now Deconica montana), was in the non-bluing clade, but in 2010 the type species was changed to '' P. semilanceata'', a member of the bluing clade. A 2006 molecular phylogenetic study of the Agaricales by Matheny and colleagues, further demonstrated the separation of the bluing and non-bluing clades of ''Psilocybe'' in a larger, strongly supported phylogenetic tree of the Agaricales. ''Psilocybe'' h ...
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Galerina Marginata
''Galerina marginata'', known colloquially as funeral bell, deadly skullcap, autumn skullcap or deadly galerina, is a species of extremely poisonous mushroom-forming fungus in the family Hymenogastraceae of the order Agaricales. It contains the same deadly amatoxins found in the death cap ('' Amanita phalloides''). Ingestion in toxic amounts causes severe liver damage with vomiting, diarrhea, hypothermia, and eventual death if not treated rapidly. About ten poisonings have been attributed to the species now grouped as ''G. marginata'' over the last century. ''G. marginata'' is widespread in the Northern Hemisphere, including Europe, North America, and Asia, and has also been found in Australia. It is a wood-rotting fungus that grows predominantly on decaying conifer wood. The fruit bodies of the mushroom have brown to yellow-brown caps that fade in color when drying. The gills are brownish and give a rusty spore print. A well-defined membranous ring is typically ...
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Washington (state)
Washington (), officially the State of Washington, is a state in the Pacific Northwest region of the Western United States. Named for George Washington—the first U.S. president—the state was formed from the western part of the Washington Territory, which was ceded by the British Empire in 1846, by the Oregon Treaty in the settlement of the Oregon boundary dispute. The state is bordered on the west by the Pacific Ocean, Oregon to the south, Idaho to the east, and the Canadian province of British Columbia to the north. It was admitted to the Union as the 42nd state in 1889. Olympia is the state capital; the state's largest city is Seattle. Washington is often referred to as Washington state to distinguish it from the nation's capital, Washington, D.C. Washington is the 18th-largest state, with an area of , and the 13th-most populous state, with more than 7.7 million people. The majority of Washington's residents live in the Seattle metropolitan area, the center o ...
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