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Proactiv Solution
Proactiv is an American brand of skin-care products developed by two American dermatologists, Katie Rodan and Kathy A. Fields, and launched in 1995 by Guthy-Renker, a California-based direct marketing company, that is endorsed by famous celebrities The range includes moisturizers, body washes and treatment products, but the brand is known for its three-step anti-acne kit consisting of a cleanser, toner and lotion. Proactiv+, a reformulation of the three-step kit, was introduced in 2013, and in 2017, ProactivMD launches powered by Adapalene. As a result of its celebrity endorsements and infomercials, Proactiv is one of the most popular skincare brands of all time, according to the ''Journal of Clinical and Aesthetic Dermatology''. Sales amounted to $800 million a year as of 2010, with a media budget of nearly $200 million and $12–15 million for celebrity fees. The product is mostly sold at ULTA Beauty, Target, and online as single-unit items or as part of a continuity program. ...
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Guthy-Renker
Guthy-Renker ( ) is a California-based direct-response marketing company that sells health and beauty products directly to consumers through infomercials, television ads, direct mail, telemarketing, e-mail marketing, and the Internet. Many of its products are endorsed by celebrities including actresses and musicians The company started marketing self-help products endorsed by Fran Tarkenton and motivational speaker Tony Robbins, previous products also included exercise equipment such as a pilates program, called the Malibu Pilates system'', endorsed by actress Susan Lucci and Instant Abs by model Heidi Klum Guthy-Renker was founded in November 1988 by Bill Guthy and Greg Renker. In 1995, it began distributing the acne treatment program Proactiv, which became responsible for more than half its revenues by 2005. The company also created seven subsidiaries in the late 1990s for different products and advertising channels. In 1996, it founded infomercial channel, ''GRTV'', whi ...
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Neutrogena
Neutrogena Corporation, trading as Neutrogena, is an American company that markets skin care, hair care and cosmetics owned by parent company Johnson & Johnson and is headquartered in Los Angeles, California.Neutrogena.com ,
According to product advertising at their website, Neutrogena products are distributed in more than 70 countries. Neutrogena was founded in 1930 by Emanuel Stolaroff, and was originally a cosmetics company named Natone. Johnson & Johnson acquired the independent company in 1994. The company originally supplied to department stores and salons that catered for the .


History

In 1930, Emanuel Stolaroff star ...
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Cutibacterium Acnes
''Cutibacterium acnes'' (formerly ''Propionibacterium acnes'') is the relatively slow-growing, typically aerotolerant Anaerobic organism, anaerobic, gram-positive bacterium (rod) linked to the skin condition of acne vulgaris, acne; it can also cause chronic blepharitis and endophthalmitis, the latter particularly following intraocular surgery. Its genome has been sequenced and a study has shown several genes can generate enzymes for degrading skin and proteins that may be immunogenic (activating the immune system). The species is largely commensalism, commensal and part of the skin flora present on most healthy adult humans' skin. It is usually just barely detectable on the skin of healthy preadolescents. It lives, among other things, primarily on fatty acids in sebum secreted by sebaceous glands in the Hair follicle, follicles. It may also be found throughout the gastrointestinal tract. Originally identified as ''Bacillus acnes'', it was later named ''Propionibacterium acnes'' ...
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Benzoyl Peroxide
Benzoyl peroxide is a chemical compound (specifically, an organic peroxide) with structural formula , often abbreviated as (BzO)2. In terms of its structure, the molecule can be described as two benzoyl (, Bz) groups connected by a peroxide (). It is a white granular solid with a faint odour of benzaldehyde, poorly soluble in water but soluble in acetone, ethanol, and many other organic solvents. Benzoyl peroxide is an oxidizer, but it is principally used as in the production of polymers. Benzoyl peroxide is mainly used in production of plastics and for bleaching flour, hair, plastics and textiles. Synthesis, structure, and chemical reactivity The original 1858 synthesis by Liebig reacted benzoyl chloride with barium peroxide, a reaction described by the following idealized equation: : Benzoyl peroxide is usually prepared by treating hydrogen peroxide with benzoyl chloride under alkaline conditions. : As in many other peroxides, the C-O-O-C linkage has a dihedral angle ...
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Astringent
An astringent (sometimes called adstringent) is a chemical that shrinks or constricts body tissues. The word derives from the Latin ''adstringere'', which means "to bind fast". Calamine lotion, witch hazel, and yerba mansa, a Californian plant, are astringents. Astringency, the dry, puckering or numbing mouthfeel caused by the tannins in unripe fruits, lets the fruit mature by deterring eating. Ripe fruits and fruit parts including blackthorn (sloe berries), ''Aronia'' chokeberry, chokecherry, bird cherry, rhubarb, quince and persimmon fruits (especially those which are unripe), banana skins (or unripe bananas), cashew fruits and acorns are astringent. Citrus fruits, like lemons, are somewhat astringent. Tannins, being a kind of polyphenol, bind salivary proteins and make them precipitate and aggregate, producing a rough, "sandpapery", or dry sensation in the mouth. The tannins in some teas, coffee, and red grape wines like Cabernet Sauvignon and Merlot produce mild as ...
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Witch Hazel (astringent)
Witch-hazels or witch hazels (''Hamamelis'') are a genus of flowering plants in the family Hamamelidaceae, with three species in North America ('' H. ovalis'', '' H. virginiana'', and '' H. vernalis''), and one each in Japan ('' H. japonica'') and China ('' H. mollis''). The North American species are occasionally called winterbloom. Growth The witch-hazels are deciduous shrubs or (rarely) small trees growing to 3 to 7.5 m tall, even more rarely to 12 m tall. The leaves are alternately arranged, oval, 5 to 15 cm long, and 2.5 to 10 cm wide, with a smooth or wavy margin. The genus name, ''Hamamelis'', means "together with fruit", referring to the simultaneous occurrence of flowers with the maturing fruit from the previous year. ''H. virginiana'' blooms in September–November while the other species bloom from January–March. Each flower has four slender strap-shaped petals 1 to 2 cm long, pale to dark yellow, orange, or red. The fruit is a two-part capsule ...
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Glycolic Acid
Glycolic acid (or hydroxyacetic acid; chemical formula HOCH2CO2H) is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water. It is used in various skin-care products. Glycolic acid is widespread in nature. A glycolate (sometimes spelled "glycollate") is a salt or ester of glycolic acid. History The name "glycolic acid" was coined in 1848 by French chemist Auguste Laurent (1807–1853). He proposed that the amino acid glycine—which was then called ''glycocolle''—might be the amine of a hypothetical acid, which he called "glycolic acid" (''acide glycolique''). Glycolic acid was first prepared in 1851 by German chemist Adolph Strecker (1822–1871) and Russian chemist Nikolai Nikolaevich Sokolov (1826–1877). They produced it by treating hippuric acid with nitric acid and nitrogen dioxide to form an ester of benzoic acid and glycolic acid (C6H5C(=O)OCH2COOH), which they called "benzoglycolic acid" (''Benzoglykolsäure''; also benzoyl glycolic acid). ...
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Nestlé
Nestlé S.A. (; ; ) is a Switzerland, Swiss multinational food and drink processing conglomerate corporation headquartered in Vevey, Vaud, Switzerland. It is the largest publicly held food company in the world, measured by revenue and other metrics, since 2014."Nestlé's Brabeck: We have a "huge advantage" over big pharma in creating medical foods"
, ''CNN Money'', 1 April 2011
It ranked No. 64 on the Fortune Global 500, ''Fortune'' Global 500 in 2017 and No. 33 in the 2016 edition of the ''Forbes'' Global 2000 list of largest public companies. Nestlé's products include baby food (some including human milk oligosaccharides), medical food, bottled water, breakfast cereals, coffee and tea, confectionery, ...
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Cindy Crawford
Cynthia Ann Crawford (born February 20, 1966) is an American model, actress and television personality. During the 1980s and 1990s, she was among the most popular supermodels and a ubiquitous presence on magazine covers, runways, as well as fashion campaigns. She subsequently expanded into acting and business ventures. Early life Crawford was born in DeKalb, Illinois, on February 20, 1966, the daughter of Dan Crawford and Jennifer Sue Crawford-Moluf (née Walker). She has two sisters, Chris and Danielle, and a brother, Jeffery, who died of childhood leukemia at age 3. On social media, she has stated that her family had been in the United States for generations and that her ancestry was mostly German, English, and French. She is Christian. Appearing in an episode of '' Who Do You Think You Are?'' in 2013, she discovered that her ancestors included European nobility and that she was descended from Charlemagne. In her sophomore year at high school, she received a call from a loca ...
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Wen Hair Care
Wen Hair Care, stylized as WEN Hair Care, is an American hair care brand founded by Chaz Dean. History Wen Hair Care was founded by celebrity hairstylist Chaz Dean. The company is most well known for producing cleansing conditioners marketed towards no-poo hair treatment methods, similar to the Curly Girl Method. Wen products are sold by Dean and Guthy-Renker. In January 2015, actress Brooke Shields became the official brand ambassador for Wen Hair Care. Controversy Wen was at the center of a class-action lawsuit which alleged that the product had caused damage to hair after use. In March 2016, the FDA opened an investigation into complaints about Wen Hair Care products by consumers. In October 2016, Wen agreed to settle out of court for a total of $26 million without admitting any wrongdoing. The lawsuits and investigations prompted researchers to submit a letter to JAMA, calling for a higher level of regulations in the personal care industry, including allowing the FDA ...
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Victoria Principal
Vicki Ree Principal (born January 3, 1950),Born January 3, 1950 as per travel manifests at ancestry.com, showing Vicki R. Principal and her mother, Ree V. Principal here, departing Southampton, England, on January 20, 1958, for New York (age given for Vicki R. Principal is 8; birthdate is January 3, 1950)
later known as Victoria Principal, is an American actress, producer, entrepreneur, and author, best known for her role as
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Greg Renker
Gregory Renker (born 1957), is best known for cofounding Guthy-Renker with partner Bill Guthy. He was born in Phoenix, Arizona in 1957 and had eight siblings. Growing up, Renker's family moved a lot due to his father's work managing country clubs and hotels. Renker worked his way through college at the San Diego State University and married Stacey Renker several years later. Renker credited the Eisenhower hospital for saving his life with an emergency heart bypass surgery and for saving his wife's life from a flu condition. After he recovered, the couple led a donation drive, which led to the creation of The Renker Wellness Center and a 24-room hospital facility called The Greg & Stacey Renker Pavilion. Renker met future business partner Bill Guthy at one of the country clubs managed by his father. The two both enjoyed self-help books and founded Guthy-Renker together to market self-help products in 1988. The company grew into one of the largest direct-response companies on the ma ...
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