Preparation H
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Preparation H
Preparation H is an American brand of medications that is made by Pfizer, used in the treatment of hemorrhoids. Hemorrhoids are caused at least in part by inflamed blood vessels, and most versions of Preparation H work by reducing inflammation in blood vessels. The company that makes this product incorporated in 1926 as American Home Products (AHP) and "one of AHP's earliest prizes was the acquisition of a sunburn oil in 1935 that the company transformed into Preparation H, which became one of the world's best-selling hemorrhoid treatments." AHP changed its name to Wyeth in 2002, and was then bought by Pfizer in 2009, which was reported to have paid $68 billion. Formulations Several formulations have been produced. Some are in a water-based gel while others are petroleum jelly-based, and the suppositories use a base of cocoa butter. It also comes as a medicated wipe. The active ingredients range from simple caffeine moisturizers with witch-hazel astringent to preparations contain ...
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Pfizer
Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer (1824–1906) and his cousin Charles F. Erhart (1821–1891). Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company has several blockbuster drugs or products that each generate more than billion in annual revenues. In 2020, 52% of the company's revenues came from the United States, 6% came from each of China and Japan, and 36% came from other countries. Pfizer was a component of the Dow Jones Industrial Average stock market index from 2004 to August 2020. The company ranks 64th on the Fortune 500 and 49th on the Forbes Global 2000. History 1849–1950: Early history Pfizer was founded in 1849 by Charles Pfizer and Charles F. Erhart, two cousins who had i ...
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Yeast Extract
Yeast extracts consist of the cell contents of yeast without the cell walls; they are used as food additives or flavorings, or as nutrients for bacterial culture media. They are often used to create savory flavors and umami taste sensations, and can be found in a large variety of packaged food, including frozen meals, crackers, snack foods, gravy, stock and more. They are rich in B vitamins (but not B12). Yeast extracts and fermented foods contain glutamic acid (free glutamates), an amino acid which adds an umami flavor. Glutamic acid is found in meat, cheese, fungi (mushrooms and yeast), and vegetables—such as broccoli, and tomatoes. The heat-autolytic process to make yeast extract of the autolysate type was invented in the 19th century by Justus von Liebig. Yeast cells are heated until they rupture, then the cells' own digestive enzymes break their proteins down into simpler compounds (amino acids and peptides), a process called autolysis. The insoluble cell walls are the ...
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Products Introduced In 1935
Product may refer to: Business * Product (business), an item that serves as a solution to a specific consumer problem. * Product (project management), a deliverable or set of deliverables that contribute to a business solution Mathematics * Product (mathematics) Algebra * Direct product Set theory * Cartesian product of sets Group theory * Direct product of groups * Semidirect product * Product of group subsets * Wreath product * Free product * Zappa–Szép product (or knit product), a generalization of the direct and semidirect products Ring theory * Product of rings * Ideal operations, for product of ideals Linear algebra * Scalar multiplication * Matrix multiplication * Inner product, on an inner product space * Exterior product or wedge product * Multiplication of vectors: ** Dot product ** Cross product ** Seven-dimensional cross product ** Triple product, in vector calculus * Tensor product Topology * Product topology Algebraic topology * Cap product * Cup product * ...
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Pfizer Brands
Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer (1824–1906) and his cousin Charles F. Erhart (1821–1891). Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company has several blockbuster drugs or products that each generate more than billion in annual revenues. In 2020, 52% of the company's revenues came from the United States, 6% came from each of China and Japan, and 36% came from other countries. Pfizer was a component of the Dow Jones Industrial Average stock market index from 2004 to August 2020. The company ranks 64th on the Fortune 500 and 49th on the Forbes Global 2000. History 1849–1950: Early history Pfizer was founded in 1849 by Charles Pfizer and Charles F. Erhart, two cousins who had im ...
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American Inventions
The following articles cover the timeline of United States inventions: *Timeline of United States inventions (before 1890), before the turn of the century * Timeline of United States inventions (1890–1945), before World War II *Timeline of United States inventions (1946–1991), for the post-war era *Timeline of United States inventions (after 1991), after the Fall of the Soviet Union {{DEFAULTSORT:Timeline of United States Inventions United States inventions United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
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Mass Fraction (chemistry)
In chemistry, the mass fraction of a substance within a mixture is the ratio w_i (alternatively denoted Y_i) of the mass m_i of that substance to the total mass m_\text of the mixture. Expressed as a formula, the mass fraction is: : w_i = \frac . Because the individual masses of the ingredients of a mixture sum to m_\text, their mass fractions sum to unity: : \sum_^ w_i = 1. Mass fraction can also be expressed, with a denominator of 100, as percentage by mass (in commercial contexts often called ''percentage by weight'', abbreviated ''wt%''; see mass versus weight). It is one way of expressing the composition of a mixture in a dimensionless size; mole fraction (percentage by moles, mol%) and volume fraction ( percentage by volume, vol%) are others. When the prevalences of interest are those of individual chemical elements, rather than of compounds or other substances, the term ''mass fraction'' can also refer to the ratio of the mass of an element to the total mass of a sampl ...
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Greece
Greece,, or , romanized: ', officially the Hellenic Republic, is a country in Southeast Europe. It is situated on the southern tip of the Balkans, and is located at the crossroads of Europe, Asia, and Africa. Greece shares land borders with Albania to the northwest, North Macedonia and Bulgaria to the north, and Turkey to the northeast. The Aegean Sea lies to the east of the Geography of Greece, mainland, the Ionian Sea to the west, and the Sea of Crete and the Mediterranean Sea to the south. Greece has the longest coastline on the Mediterranean Basin, featuring List of islands of Greece, thousands of islands. The country consists of nine Geographic regions of Greece, traditional geographic regions, and has a population of approximately 10.4 million. Athens is the nation's capital and List of cities and towns in Greece, largest city, followed by Thessaloniki and Patras. Greece is considered the cradle of Western culture, Western civilization, being the birthplace of Athenian ...
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George Sperti
George Speri Sperti (January 17, 1900, Covington, Kentucky – April 29, 1991, Cincinnati, Ohio) was an Italian-American inventor who invented Preparation H hemorrhoid medication. He also invented the Sperti Ultraviolet Lamp, Aspercreme for pain relief, and KVa Power Meter. Sperti graduated from the University of Cincinnati in 1923. Shortly afterwards he was named Director of the Research Laboratory. His invention of an ultraviolet lamp to irradiate milk to add Vitamin D without changing the flavor was sold to General Foods for US$300,000. Sperti donated the entire amount to the University to continue basic research, and went on to develop a successful business line of ultraviolet sunlamps. He also invented the first practical technique for freeze-drying orange juice concentrate. He donated most of the money he received from 127 patents to the University of Cincinnati and the Institutum Divi Thomae, which he co-founded in 1935 in collaboration with the Archdiocese of Cincinnati ...
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Shark Liver Oil
Shark liver oil is an oil obtained from the livers of sharks. It has been used for centuries as a folk remedy to promote the healing of wounds and as a remedy for respiratory tract and digestive system problems.
'' American Cancer Society''. Retrieved 28 March 2013.
Gupta P, K Singhal, AK Jangra, V Nautiyal and A Pandey (2012
"Shark liver oil: A review"
''Asian Journal of Pharmaceutical Education and Research'', 1 (2): 1-15.
It is still promoted as a
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Hemorrhoid
Hemorrhoids (or haemorrhoids), also known as piles, are vascular structures in the anal canal. In their normal state, they are cushions that help with stool control. They become a disease when swollen or inflamed; the unqualified term ''hemorrhoid'' is often used to refer to the disease. The signs and symptoms of hemorrhoids depend on the type present. Internal hemorrhoids often result in painless, bright red rectal bleeding when defecating. External hemorrhoids often result in pain and swelling in the area of the anus. If bleeding occurs, it is usually darker. Symptoms frequently get better after a few days. A skin tag may remain after the healing of an external hemorrhoid. While the exact cause of hemorrhoids remains unknown, a number of factors that increase pressure in the abdomen are believed to be involved. This may include constipation, diarrhea, and sitting on the toilet for long periods. Hemorrhoids are also more common during pregnancy. Diagnosis is made by lookin ...
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Hydrocortisone
Hydrocortisone is the name for the hormone cortisol when supplied as a medication. Uses include conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, rheumatoid arthritis, dermatitis, asthma, and COPD. It is the treatment of choice for adrenocortical insufficiency. It can be given by mouth, topically, or by injection. Stopping treatment after long-term use should be done slowly. Side effects may include mood changes, increased risk of infection, and edema (swelling). With long-term use common side effects include osteoporosis, upset stomach, physical weakness, easy bruising, and candidiasis (yeast infections). While used, it is unclear if it is safe during pregnancy. Hydrocortisone is a glucocorticoid and works as an anti-inflammatory and by immune suppression. Hydrocortisone was patented in 1936 and approved for medical use in 1941. It is on the World Health Organization's List of Essential Medicines. It is available as a ...
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Pramoxine
Pramocaine (International Nonproprietary Name, INN and British Approved Name, BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. During research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent. Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans. Like other local anesthetics, pramocaine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness. Use Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, p ...
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