Preben Von Magnus
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Preben Von Magnus
Preben Christian Alexander von Magnus (25 February 1912 – 9 August 1973) was a Danish virologist who is known for his research on influenza, polio vaccination and monkeypox. He gave his name to the Von Magnus phenomenon. In the 1950s, together with his wife the virologist Herdis von Magnus, he directed the first Danish vaccination programme against polio. In 1958, he was the first to confirm the identity of the monkeypox virus and to describe monkeypox in laboratory crab-eating Macaques during two outbreaks of the disease in the summer and autumn of that year. In 1959 he was appointed director of the Statens Serum Institut. He represented Denmark at the 1959 Pugwash Conferences on Science and World Affairs where he explained that respiratory viruses such as influenza and the common cold were unsuitable as biological weapons. He became a Knight of the Order of the Dannebrog in 1965. Early life Preben von Magnus was born in Copenhagen on 25 February 1912 to the Livonian lan ...
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Von Magnus Phenomenon
The von Magnus phenomenon describes the generation of defective interfering particles (DIPs) by viruses. It was first observed by Preben von Magnus in influenza viruses, after the serial passage of undiluted allantoic fluid in eggs. References {{reflist Virology ...
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University Of Copenhagen
The University of Copenhagen ( da, Københavns Universitet, KU) is a prestigious public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia after Uppsala University, and ranks as one of the top universities in the Nordic countries, Europe and the world. Its establishment sanctioned by Pope Sixtus IV, the University of Copenhagen was founded by Christian I of Denmark as a Catholic teaching institution with a predominantly Theology, theological focus. In 1537, it was re-established by King Christian III as part of the Lutheran Reformation. Up until the 18th century, the university was primarily concerned with educating clergymen. Through various reforms in the 18th and 19th century, the University of Copenhagen was transformed into a modern, Secularism, secular university, with science and the humanities replacing theology as the main subjects studied and taught. Th ...
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Viral Replication
Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. Through the generation of abundant copies of its genome and packaging these copies, the virus continues infecting new hosts. Replication between viruses is greatly varied and depends on the type of genes involved in them. Most DNA viruses assemble in the nucleus while most RNA viruses develop solely in cytoplasm. Viral production / replication Viruses multiply only in living cells. The host cell must provide the energy and synthetic machinery and the low- molecular-weight precursors for the synthesis of viral proteins and nucleic acids. The virus replication occurs in seven stages, namely; # Attachment # Entry, # Uncoating, # Transcription / mRNA production, # Synthesis of virus components, # Virion assembly and # Release (Liberation Stage). Attachment It is the first step of viral replication ...
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Defective Interfering Particle
Defective interfering particles (DIPs), also known as defective interfering viruses, are spontaneously generated virus mutants in which a critical portion of the particle's genome has been lost due to defective replication or non-homologous recombination. The mechanism of their formation is presumed to be as a result of template-switching during replication of the viral genome, although non-replicative mechanisms involving direct ligation of genomic RNA fragments have also been proposed. DIPs are derived from and associated with their parent virus, and particles are classed as DIPs if they are rendered non-infectious due to at least one essential gene of the virus being lost or severely damaged as a result of the defection. A DIP can usually still penetrate host cells, but requires another fully functional virus particle (the 'helper' virus) to co-infect a cell with it, in order to provide the lost factors. DIPs were first observed as early as the 1950s by Von Magnus and Schlesinge ...
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Serology
Serology is the scientific study of Serum (blood), serum and other body fluids. In practice, the term usually refers to the medical diagnosis, diagnostic identification of Antibody, antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a Acute hemolytic transfusion reaction, mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease). In either case, the procedure is simple. Serological tests Serological tests are diagnostic methods that are used to identify antibodies and antigens in a patient's sample. Serological tests may be performed to diagnose infections and autoimmune illnesses, to check if a person has immunity (medical), immunity to certain diseases, and in many other situations, such as determining an individual's blood type. Serological tests may also be used in forensic serology to investigate crime scene evid ...
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Bacteriology
Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classification, and characterization of bacterial species. Because of the similarity of thinking and working with microorganisms other than bacteria, such as protozoa, fungi, and viruses, there has been a tendency for the field of bacteriology to extend as microbiology. The terms were formerly often used interchangeably. However, bacteriology can be classified as a distinct science. Overview Definition Bacteriology is the study of bacteria and their relation to medicine. Bacteriology evolved from physicians needing to apply the germ theory to address the concerns relating to disease spreading in hospitals the 19th century. Identification and characterizing of bacteria being associated to diseases led to advances in pathogenic bacteriology. K ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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MS Jutlandia
MS ''Jutlandia'' ( lat.: Jutland) was contracted by and built for the East Asiatic Company (EAC) in 1934, as a combined passenger and cargo ship at EAC's Nakskov Shipyard, Denmark. Following an extended operational life in which she also served as a hospital ship and a royal yacht, she was finally decommissioned in 1965. History ''Jutlandia'' was contracted by EAC in 1934, to replace older ships on the then regular service between Copenhagen and Bangkok. She operated on this route from November 1934, until January 1940, and again from 1954 to the end of 1964. ''Jutlandia'' was the only ship in the EAC fleet to be designed with a Maierform bow. She is the second of so far three ships of the same name. Passengers were accommodated in nine single and twenty-nine double staterooms with all double staterooms provided with a private bath. The dining room could seat seventy with smoking room, ladies lounge, bar and foredeck swimming pool also provided for passenger use. A dining and p ...
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UNRRA
United Nations Relief and Rehabilitation Administration (UNRRA) was an international relief agency, largely dominated by the United States but representing 44 nations. Founded in November 1943, it was dissolved in September 1948. it became part of the United Nations in 1945. Its purpose was to "plan, co-ordinate, administer or arrange for the administration of measures for the relief of victims of war in any area under the control of any of the United Nations through the provision of food, fuel, clothing, shelter and other basic necessities, medical and other essential services". Its staff of civil servants included 12,000 people, with headquarters in New York. Funding came from many nations, and totalled $3.7 billion, of which the United States contributed $2.7 billion; Britain, $625 million; and Canada, $139 million. UNRRA cooperated closely with dozens of volunteer charitable organizations, who sent hundreds of their own staff to work alongside UNRRA. In operation for only four ...
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Thesis
A thesis ( : theses), or dissertation (abbreviated diss.), is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings.International Standard ISO 7144: DocumentationâPresentation of theses and similar documents International Organization for Standardization, Geneva, 1986. In some contexts, the word "thesis" or a cognate is used for part of a bachelor's or master's course, while "dissertation" is normally applied to a doctorate. This is the typical arrangement in American English. In other contexts, such as within most institutions of the United Kingdom and Republic of Ireland, the reverse is true. The term graduate thesis is sometimes used to refer to both master's theses and doctoral dissertations. The required complexity or quality of research of a thesis or dissertation can vary by country, university, or program, and the required minimum study period may thus vary significantly in d ...
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Doctorate
A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''licentia docendi'' ("licence to teach"). In most countries, a research degree qualifies the holder to teach at university level in the degree's field or work in a specific profession. There are a number of doctoral degrees; the most common is the Doctor of Philosophy (PhD), awarded in many different fields, ranging from the humanities to scientific disciplines. In the United States and some other countries, there are also some types of technical or professional degrees that include "doctor" in their name and are classified as a doctorate in some of those countries. Professional doctorates historically came about to meet the needs of practitioners in a variety of disciplines. Many universities also award honorary doctorates to individuals d ...
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Long-tailed Macaque (Macaca Fascicularis) Juvenile
The crab-eating macaque (''Macaca fascicularis''), also known as the long-tailed macaque and referred to as the cynomolgus monkey in laboratories, is a cercopithecine primate native to Southeast Asia. A species of macaque, the crab-eating macaque has a long history alongside humans. The species has been alternately seen as an agricultural pest, a sacred animal, and, more recently, the subject of medical experiments. The crab-eating macaque lives in matrilineal social groups of up to eight individuals dominated by females. Male members leave the group when they reach puberty. It is an opportunistic omnivore and has been documented using tools to obtain food in Thailand and Myanmar. The crab-eating macaque is a known invasive species and a threat to biodiversity in several locations, including Hong Kong and western New Guinea. The significant overlap in macaque and human living space has resulted in greater habitat loss, synanthropic living, and inter- and intraspecies conflicts ov ...
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