Plasmodium Youngi
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Plasmodium Youngi
''Plasmodium youngi'' is a protozoan parasite which can cause malaria in certain primates. It is known to infect and cause severe disease in Malayan gibbons. History The parasite was first identified in blood smears from a young Malayan gibbon (''Hylobates lar lar'') in Kelantan, Malaysia in 1964. It was named after the American malaria researcher Martin D. Young. Pathogenesis In the Malayan gibbon, the parasite causes severe malaria. Parasitemia peaks on the 12th and 16th day of infection, with up to 130,000 parasites per milliliter of blood. Parasite load remains fairly high at greater than 10,000 parasites per milliliter of blood for several weeks, before declining. Parasites are still detectable in the blood intermittently for at least 4 months. Major signs of infection are anemia and listlessness. Host Range ''P. youngi'' can cause severe disease in the Malayan gibbon. It can also infect the Black crested gibbon ('' Hylobates concolor''), although it causes onl ...
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Protozoa
Protozoa (singular: protozoan or protozoon; alternative plural: protozoans) are a group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic tissues and debris. Historically, protozoans were regarded as "one-celled animals", because they often possess animal-like behaviours, such as motility and predation, and lack a cell wall, as found in plants and many algae. When first introduced by Georg Goldfuss (originally spelled Goldfuß) in 1818, the taxon Protozoa was erected as a class within the Animalia, with the word 'protozoa' meaning "first animals". In later classification schemes it was elevated to a variety of higher ranks, including phylum, subkingdom and kingdom, and sometimes included within Protoctista or Protista. The approach of classifying Protozoa within the context of Animalia was widespread in the 19th and early 20th century, but not universal. By the 1970s, it became usual to require th ...
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Malaysia
Malaysia ( ; ) is a country in Southeast Asia. The federation, federal constitutional monarchy consists of States and federal territories of Malaysia, thirteen states and three federal territories, separated by the South China Sea into two regions: Peninsular Malaysia and Borneo's East Malaysia. Peninsular Malaysia shares a land and maritime Malaysia–Thailand border, border with Thailand and Maritime boundary, maritime borders with Singapore, Vietnam, and Indonesia. East Malaysia shares land and maritime borders with Brunei and Indonesia, and a maritime border with the Philippines and Vietnam. Kuala Lumpur is the national capital, the country's largest city, and the seat of the Parliament of Malaysia, legislative branch of the Government of Malaysia, federal government. The nearby Planned community#Planned capitals, planned capital of Putrajaya is the administrative capital, which represents the seat of both the Government of Malaysia#Executive, executive branch (the Cabine ...
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Vector (epidemiology)
In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen to another living organism; agents regarded as vectors are organisms, such as parasites or microbes. The first major discovery of a disease vector came from Ronald Ross in 1897, who discovered the malaria pathogen when he dissected a mosquito. Arthropods Arthropods form a major group of pathogen vectors with mosquitoes, flies, sand flies, lice, fleas, ticks, and mites transmitting a huge number of pathogens. Many such vectors are haematophagous, which feed on blood at some or all stages of their lives. When the insects feed on blood, the pathogen enters the blood stream of the host. This can happen in different ways. The ''Anopheles'' mosquito, a vector for malaria, filariasis, and various arthropod-borne-viruses (arboviruses), inserts its delicate mouthpart under the skin and feeds on its host's blood. The parasites the mosquito carries are usually located in its salivary gla ...
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Mosquito
Mosquitoes (or mosquitos) are members of a group of almost 3,600 species of small flies within the family Culicidae (from the Latin ''culex'' meaning " gnat"). The word "mosquito" (formed by ''mosca'' and diminutive ''-ito'') is Spanish for "little fly". Mosquitoes have a slender segmented body, one pair of wings, one pair of halteres, three pairs of long hair-like legs, and elongated mouthparts. The mosquito life cycle consists of egg, larva, pupa, and adult stages. Eggs are laid on the water surface; they hatch into motile larvae that feed on aquatic algae and organic material. These larvae are important food sources for many freshwater animals, such as dragonfly nymphs, many fish, and some birds such as ducks. The adult females of most species have tube-like mouthparts (called a proboscis) that can pierce the skin of a host and feed on blood, which contains protein and iron needed to produce eggs. Thousands of mosquito species feed on the blood of various hosts ⁠ ...
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Rhesus Macaque
The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies that are split between two groups, the Chinese-derived and the Indian-derived. Generally brown or grey in colour, it is in length with a tail and weighs . It is native to South, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and a great variety of habitats, from grasslands to arid and forested areas, but also close to human settlements. Feral colonies are found in the United States, thought to be either released by humans or escapees after hurricanes destroyed zoo and wildlife park facilities. The rhesus macaque is diurnal, arboreal, and terrestrial. It is mostly herbivorous, mainly eating fruit, but will also consume seeds, roots, buds, bark, and cereals. Studies show almost 100 different plant species in its diet. Rhesus macaques are gener ...
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Parasitemia
Parasitemia is the quantitative content of parasites in the blood. It is used as a measurement of parasite load in the organism and an indication of the degree of an active parasitic infection. Systematic measurement of parasitemia is important in many phases of the assessment of disease, such as in diagnosis and in the follow-up of therapy, particularly in the chronic phase, when cure depends on ascertaining a parasitemia of zero. The methods to be used for quantifying parasitemia depends on the parasitic species and its life cycle. For instance, in malaria, the number of blood-stage parasites can be counted using an optical microscope, on a special thick film (for low parasitemias) or thin film blood smear (for high parasitemias). The use of molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The s ...
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Hylobates Concolor
The black crested gibbon (''Nomascus concolor'') is a Critically Endangered species of gibbon found in China, Laos, and northern Vietnam, with four subspecies. Taxonomy The taxonomy of the species is confused. Previously grouped in the genus ''Hylobates'', currently four subspecies are recognised. *Central Yunnan black crested gibbon (''Nomascus concolor jingdongensis''), Yunnan province, China *West Yunnan black crested gibbon (''N. c. furvogaster''), Yunnan province, China *Laotian black crested gibbon (''N. c. lu''), Laos *Tonkin black crested gibbon (''N. c. concolor''), northern Vietnam Description The length from the head to the end of body is and it weighs from . The species exhibits sexual dichromatism, the male is completely black, while the female is a golden or buff colour with variable black patches, including a black streak on the head. Behavior Gibbons are forest dwellers and are well known for their habit of swinging between the branches of the rainfo ...
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Listlessness
In conventional usage, boredom, ennui, or tedium is an emotional and occasionally psychological state experienced when an individual is left without anything in particular to do, is listlessness and dissatisfaction arising from a lack of occupation or excitement, is not interested in their surroundings, or feels that a day or period is dull or tedious. It is also understood by scholars as a modern phenomenon which has a cultural dimension. "There is no universally accepted definition of boredom. But whatever it is, researchers argue, it is not simply another name for depression or apathy. It seems to be a specific mental state that people find unpleasant—a lack of stimulation that leaves them craving relief, with a host of behavioral, medical and social consequences." According to BBC News, boredom "...can be a dangerous and disruptive state of mind that damages your health"; yet research "...suggest that without boredom we couldn't achieve our creative feats." In ''Experi ...
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Anemia
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen due to a lower than normal number of red blood cells, or a reduction in the amount of hemoglobin. When anemia comes on slowly, the symptoms are often vague, such as tiredness, weakness, shortness of breath, headaches, and a reduced ability to exercise. When anemia is acute, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst. Anemia must be significant before a person becomes noticeably pale. Symptoms of anemia depend on how quickly hemoglobin decreases. Additional symptoms may occur depending on the underlying cause. Preoperative anemia can increase the risk of needing a blood transfusion following surgery. Anemia can be temporary or long term and can range from mild to severe. Anemia can be caused by blood loss, decreased red blood cell production, and increased red blood cell breakdown. Causes o ...
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Milliliter
The litre (international spelling) or liter (American English spelling) (SI symbols L and l, other symbol used: ℓ) is a metric unit of volume. It is equal to 1 cubic decimetre (dm3), 1000 cubic centimetres (cm3) or 0.001 cubic metre (m3). A cubic decimetre (or litre) occupies a volume of (see figure) and is thus equal to one-thousandth of a cubic metre. The original French metric system used the litre as a base unit. The word ''litre'' is derived from an older French unit, the '' litron'', whose name came from Byzantine Greek—where it was a unit of weight, not volume—via Late Medieval Latin, and which equalled approximately 0.831 litres. The litre was also used in several subsequent versions of the metric system and is accepted for use with the SI,Bureau International des Poids et Me ...
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Parasitemia
Parasitemia is the quantitative content of parasites in the blood. It is used as a measurement of parasite load in the organism and an indication of the degree of an active parasitic infection. Systematic measurement of parasitemia is important in many phases of the assessment of disease, such as in diagnosis and in the follow-up of therapy, particularly in the chronic phase, when cure depends on ascertaining a parasitemia of zero. The methods to be used for quantifying parasitemia depends on the parasitic species and its life cycle. For instance, in malaria, the number of blood-stage parasites can be counted using an optical microscope, on a special thick film (for low parasitemias) or thin film blood smear (for high parasitemias). The use of molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The s ...
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Kelantan
Kelantan (; Jawi: ; Kelantanese Malay: ''Klate'') is a state in Malaysia. The capital is Kota Bharu and royal seat is Kubang Kerian. The honorific name of the state is ''Darul Naim'' (Jawi: ; "The Blissful Abode"). Kelantan is located in the north-eastern corner of the peninsula. Kelantan, which is said to translate as the "Land of Lightning" (see alternate theories below), is an agrarian state with green paddy fields, rustic fishing villages and casuarina-lined beaches. Kelantan is home to some of the most ancient archaeological discoveries in Malaysia, including several prehistoric aboriginal settlements. Due to Kelantan's relative isolation and largely rural lifestyle, Kelantanese culture differs somewhat from Malay culture in the rest of the peninsula; this is reflected in the cuisine, arts and the unique Kelantanese Malay language, which is unintelligible even for some speakers of standard Malay. Kelantan is positioned in the north-east of the Malay Peninsula. It is bor ...
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