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Pipistrellus Bat Coronavirus HKU5
''Pipistrellus bat coronavirus HKU5'' (''Bat-CoV HKU5'') is an enveloped, positive-sense single-stranded RNA mammalian Group 2 '' Betacoronavirus'' discovered in Japanese ''Pipistrellus'' in Hong Kong. This strain of coronavirus is closely related to the newly identified novel MERS-CoV that is responsible for the 2012 '' Middle East respiratory syndrome-related coronavirus'' outbreaks in Saudi Arabia, Jordan, United Arab Emirates, the United Kingdom, France, and Italy. Transmission The exact means of transmission to humans is not yet well known. However, it has been demonstrated that betaCoV's including HKU5 have the propensity to recombine and cause interspecies transmission. However, this is not seen in Group C betaCov's to which MERS-CoV is most closely related. See also * London1 novel CoV/2012 * Severe acute respiratory syndrome Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Positive-sense Single-stranded RNA Virus
Positive-strand RNA viruses (+ssRNA viruses) are a group of related viruses that have positive-sense, single-stranded genomes made of ribonucleic acid. The positive-sense genome can act as messenger RNA (mRNA) and can be directly translated into viral proteins by the host cell's ribosomes. Positive-strand RNA viruses encode an RNA-dependent RNA polymerase (RdRp) which is used during replication of the genome to synthesize a negative-sense antigenome that is then used as a template to create a new positive-sense viral genome. Positive-strand RNA viruses are divided between the phyla ''Kitrinoviricota'', '' Lenarviricota'', and ''Pisuviricota'' (specifically classes ''Pisoniviricetes'' and '' Stelpavirictes'') all of which are in the kingdom '' Orthornavirae'' and realm '' Riboviria''. They are monophyletic and descended from a common RNA virus ancestor. In the Baltimore classification system, +ssRNA viruses belong to Group IV. Positive-sense RNA viruses include pat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Betacoronavirus
''Betacoronavirus'' (β-CoVs or Beta-CoVs) is one of four genera (''Alpha''-, ''Beta-'', '' Gamma-'', and '' Delta-'') of coronaviruses. Member viruses are enveloped, positive-strand RNA viruses that infect mammals (of which humans are part). The natural reservoir for betacoronaviruses are bats and rodents. Rodents are the reservoir for the subgenus '' Embecovirus'', while bats are the reservoir for the other subgenera. The coronavirus genera are each composed of varying viral lineages with the betacoronavirus genus containing four such lineages: A, B, C, D. In older literature, this genus is also known as "group 2 coronaviruses". The genus is in the subfamily ''Orthocoronavirinae'' in the family ''Coronaviridae'', of the order ''Nidovirales''. The betacoronaviruses of the greatest clinical importance concerning humans are OC43 and HKU1 (which can cause the common cold) of lineage A, SARS-CoV and SARS-CoV-2 (which has caused the disease COVID-19) of lineage B, and MERS-Co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pipistrellus
''Pipistrellus'' is a genus of bats in the family Vespertilionidae and subfamily Vespertilioninae. The name of the genus is derived from the Italian word , meaning "bat" (from Latin "bird of evening, bat"). The size of the genus has been considerably reduced as a result of work during the 1990s and 2000s, with genera such as '' Arielulus'', ''Hypsugo'', '' Falsistrellus'', '' Neoromicia'', '' Parastrellus'', '' Perimyotis'', '' Scotozous'', and '' Vespadelus'' being split off. Still, molecular evidence suggests the genus is not monophyletic. Several other genera in the subfamily Vespertilioninae have also been merged with ''Pipistrellus'' in previous classifications. Species in the genus may be referred to as "pipistrelles" or "pipistrelle bats", though these terms are also used for species now placed in other genera, such as the western pipistrelle (''Parastrellus hesperus'') and eastern pipistrelle (''Perimyotis subflavus'') of North America. Species of the southern hemi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middle East Respiratory Syndrome-related Coronavirus
''Middle East respiratory syndrome–related coronavirus'' (''MERS-CoV''), or EMC/2012 ( HCoV-EMC/2012), is the virus that causes Middle East respiratory syndrome (MERS). It is a species of coronavirus which infects humans, bats, and camels. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the DPP4 receptor. The species is a member of the genus ''Betacoronavirus'' and subgenus ''Merbecovirus''. Initially called simply novel coronavirus or nCoV, it was first reported in June 2012 after genome sequencing of a virus isolated from sputum samples from a person who fell ill in a 2012 outbreak of a new flu-like respiratory illness. By July 2015, MERS-CoV cases had been reported in over 21 countries, in Europe, North America and Asia as well as the Middle East. MERS-CoV is one of several viruses identified by the World Health Organization (WHO) as a likely cause of a future epidemic. They list it for urgent resear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saudi Arabia
Saudi Arabia, officially the Kingdom of Saudi Arabia (KSA), is a country in Western Asia. It covers the bulk of the Arabian Peninsula, and has a land area of about , making it the fifth-largest country in Asia, the second-largest in the Arab world, and the largest in Western Asia and the Middle East. It is bordered by the Red Sea to the west; Jordan, Iraq, and Kuwait to the north; the Persian Gulf, Qatar and the United Arab Emirates to the east; Oman to the southeast; and Yemen to the south. Bahrain is an island country off the east coast. The Gulf of Aqaba in the northwest separates Saudi Arabia from Egypt. Saudi Arabia is the only country with a coastline along both the Red Sea and the Persian Gulf, and most of its terrain consists of arid desert, lowland, steppe, and mountains. Its capital and largest city is Riyadh. The country is home to Mecca and Medina, the two holiest cities in Islam. Pre-Islamic Arabia, the territory that constitutes modern-day Saudi Ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jordan
Jordan ( ar, الأردن; tr. ' ), officially the Hashemite Kingdom of Jordan,; tr. ' is a country in Western Asia. It is situated at the crossroads of Asia, Africa, and Europe, within the Levant region, on the East Bank of the Jordan River. Jordan is bordered by Saudi Arabia to the south and east, Iraq to the northeast, Syria to the north, and the Palestinian West Bank, Israel, and the Dead Sea to the west. It has a coastline in its southwest on the Gulf of Aqaba's Red Sea, which separates Jordan from Egypt. Amman is Jordan's capital and largest city, as well as its economic, political, and cultural centre. Modern-day Jordan has been inhabited by humans since the Paleolithic period. Three stable kingdoms emerged there at the end of the Bronze Age: Ammon, Moab and Edom. In the third century BC, the Arab Nabataeans established their Kingdom with Petra as the capital. Later rulers of the Transjordan region include the Assyrian, Babylonian, Roman, Byzantine, Ras ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United Arab Emirates
The United Arab Emirates (UAE; ar, اَلْإِمَارَات الْعَرَبِيَة الْمُتَحِدَة ), or simply the Emirates ( ar, الِْإمَارَات ), is a country in Western Asia ( The Middle East). It is located at the eastern end of the Arabian Peninsula and shares borders with Oman and Saudi Arabia, while having maritime borders in the Persian Gulf with Qatar and Iran. Abu Dhabi is the nation's capital, while Dubai, the most populous city, is an international hub. The United Arab Emirates is an elective monarchy formed from a federation of seven emirates, consisting of Abu Dhabi (the capital), Ajman, Dubai, Fujairah, Ras Al Khaimah, Sharjah and Umm Al Quwain. Each emirate is governed by an emir and together the emirs form the Federal Supreme Council. The members of the Federal Supreme Council elect a president and vice president from among their members. In practice, the emir of Abu Dhabi serves as president while the ruler of Dubai is vice pre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the European mainland, continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The United Kingdom includes the island of Great Britain, the north-eastern part of the island of Ireland, and many List of islands of the United Kingdom, smaller islands within the British Isles. Northern Ireland shares Republic of Ireland–United Kingdom border, a land border with the Republic of Ireland; otherwise, the United Kingdom is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. The total area of the United Kingdom is , with an estimated 2020 population of more than 67 million people. The United Kingdom has evolved from a series of annexations, unions and separations of constituent countries over several hundred years. The Treaty of Union between ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of overseas regions and territories in the Americas and the Atlantic, Pacific and Indian Oceans. Its metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin. Its eighteen integral regions (five of which are overseas) span a combined area of and contain clos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Italy
Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical region. Italy is also considered part of Western Europe, and shares land borders with France, Switzerland, Austria, Slovenia and the enclaved microstates of Vatican City and San Marino. It has a territorial exclave in Switzerland, Campione. Italy covers an area of , with a population of over 60 million. It is the third-most populous member state of the European Union, the sixth-most populous country in Europe, and the tenth-largest country in the continent by land area. Italy's capital and largest city is Rome. Italy was the native place of many civilizations such as the Italic peoples and the Etruscans, while due to its central geographic location in Southern Europe and the Mediterranean, the country has also historicall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
London1 Novel CoV/2012
London1_novel CoV/2012 is a coronavirus strain isolated from a Qatari man in London in 2012 who was one of the first patients to come down with what has since been named Middle East respiratory syndrome-related coronavirus (MERS-CoV). The Qatari patient had traveled to Saudi Arabia from Qatar. He returned to Qatar, but when he fell ill, he traveled to London for treatment. The United Kingdom's Health Protection Agency (HPA) named the virus. Virology Phylogenetic analysis demonstrated that London1 is a ''Betacoronavirus'' with a close relationship to ''Tylonycteris bat coronavirus HKU4'' and ''Pipistrellus bat coronavirus HKU5 ''Pipistrellus bat coronavirus HKU5'' (''Bat-CoV HKU5'') is an enveloped, positive-sense single-stranded RNA mammalian Group 2 '' Betacoronavirus'' discovered in Japanese ''Pipistrellus'' in Hong Kong. This strain of coronavirus is closely relat ...''. It was found that the virus nucleic acid fragment identified in the isolate from the Qatari-London pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Severe Acute Respiratory Syndrome
Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), the first identified strain of the SARS coronavirus species, ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV). The first known cases occurred in November 2002, and the syndrome caused the 2002–2004 SARS outbreak. In the 2010s, Chinese scientists traced the virus through the intermediary of Asian palm civets to cave-dwelling horseshoe bats in Xiyang Yi Ethnic Township, Yunnan.The locality was referred to be "a cave in Kunming" in earlier sources because the Xiyang Yi Ethnic Township is administratively part of Kunming, though 70 km apart. Xiyang was identified on * For an earlier interview of the researchers about the locality of the caves, see: SARS was a relatively rare disease; at the end of the epidemic in June 2003, the incidence was 8,469 cases with a case fatality rat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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