Philip D'Arcy Hart
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Philip D'Arcy Hart
Philip Montagu D'Arcy Hart, CBE (25 June 1900 – 30 July 2006) was a seminal British medical researcher and pioneer in tuberculosis treatment. Personal life Philip D'Arcy Hart was the grandson of Samuel Montagu, 1st Baron Swaythling. He was educated at Clifton College. In 1941, he married Ruth Meyer (1913–2007), later a medical gynaecologist. They had a son, the economist Oliver Hart. Philip D'Arcy Hart died at the age of 106 in 2006. Career D'Arcy Hart became a consultant physician at University College Hospital at the age of 34. Three years later, he joined the Medical Research Council (MRC). He was a pioneer of evidence-based medicine, conducting some of the earliest randomized controlled trials on patulin in 1943 and streptomycin with Austin Bradford Hill. D'Arcy Hart became involved with much of the MRC's early research into dust diseases in coal miners. He was a member of the MRC Streptomycin in Tuberculosis Trials Committee, which is generally accepted as the ...
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United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The United Kingdom includes the island of Great Britain, the north-eastern part of the island of Ireland, and many smaller islands within the British Isles. Northern Ireland shares a land border with the Republic of Ireland; otherwise, the United Kingdom is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. The total area of the United Kingdom is , with an estimated 2020 population of more than 67 million people. The United Kingdom has evolved from a series of annexations, unions and separations of constituent countries over several hundred years. The Treaty of Union between the Kingdom of England (which included Wales, annexed in 1542) and the Kingdom of Scotland in 170 ...
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Mycobacterium Tuberculosis
''Mycobacterium tuberculosis'' (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, ''M. tuberculosis'' can appear weakly Gram-positive. Acid-fastness, Acid-fast stains such as Ziehl–Neelsen stain, Ziehl–Neelsen, or Fluorescence, fluorescent stains such as Auramine O, auramine are used instead to identify ''M. tuberculosis'' with a microscope. The physiology of ''M. tuberculosis'' is highly aerobic organism, aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the Mantoux test, tuberculin skin test, Acid-Fast Stain, acid-fast stain, Microbiological cultu ...
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English Jews
The history of the Jews in England goes back to the reign of William the Conqueror. Although it is likely that there had been some Jewish presence in the Roman period, there is no definitive evidence, and no reason to suppose that there was any community during Anglo-Saxon times. The first written record of Jewish settlement in England dates from 1070. The Jewish settlement continued until King Edward I's Edict of Expulsion in 1290. After the expulsion, there was no overt Jewish community (as opposed to individuals practising Judaism secretly) until the rule of Oliver Cromwell. While Cromwell never officially readmitted Jews to the Commonwealth of England, a small colony of Sephardic Jews living in London was identified in 1656 and allowed to remain. The Jewish Naturalisation Act of 1753, an attempt to legalise the Jewish presence in England, remained in force for only a few months. Historians commonly date Jewish Emancipation to either 1829 or 1858, while Benjamin Disraeli ...
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Men Centenarians
A man is an adult male human. Prior to adulthood, a male human is referred to as a boy (a male child or adolescent). Like most other male mammals, a man's genome usually inherits an X chromosome from the mother and a Y chromosome from the father. Sex differentiation of the male fetus is governed by the SRY gene on the Y chromosome. During puberty, hormones which stimulate androgen production result in the development of secondary sexual characteristics, thus exhibiting greater differences between the sexes. These include greater muscle mass, the growth of facial hair and a lower body fat composition. Male anatomy is distinguished from female anatomy by the male reproductive system, which includes the penis, testicles, sperm duct, prostate gland and the epididymis, and by secondary sex characteristics, including a narrower pelvis, narrower hips, and smaller breasts without mammary glands. Throughout human history, traditional gender roles have often defined ...
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English Centenarians
English usually refers to: * English language * English people English may also refer to: Peoples, culture, and language * ''English'', an adjective for something of, from, or related to England ** English national identity, an identity and common culture ** English language in England, a variant of the English language spoken in England * English languages (other) * English studies, the study of English language and literature * ''English'', an Amish term for non-Amish, regardless of ethnicity Individuals * English (surname), a list of notable people with the surname ''English'' * People with the given name ** English McConnell (1882–1928), Irish footballer ** English Fisher (1928–2011), American boxing coach ** English Gardner (b. 1992), American track and field sprinter Places United States * English, Indiana, a town * English, Kentucky, an unincorporated community * English, Brazoria County, Texas, an unincorporated community * Engli ...
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British Public Health Doctors
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * Briton (d ...
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2006 Deaths
File:2006 Events Collage V1.png, From top left, clockwise: The 2006 Winter Olympics open in Turin; Twitter is founded and launched by Jack Dorsey; The Nintendo Wii is released; Montenegro votes to declare independence from Serbia; The 2006 FIFA World Cup in Germany is won by Italy; Gol Transportes Aéreos Flight 1907 crashes in the Amazon rainforest after a mid-air collision with an Embraer Legacy 600 business jet; The 2006 Yogyakarta earthquake kills over 5,700 people; The IAU votes on the definition of "planet", which demotes Pluto and other Kuiper belt objects and redefines them as "dwarf planets"., 300x300px, thumb rect 0 0 200 200 2006 Winter Olympics rect 200 0 400 200 Twitter rect 400 0 600 200 Nintendo Wii rect 0 200 300 400 IAU definition of planet rect 300 200 600 400 2006 Montenegrin independence referendum rect 0 400 200 600 2006 Yogyakarta earthquake rect 200 400 400 600 Gol Transportes Aéreos Flight 1907 rect 400 400 600 600 2006 FIFA World Cup 2006 was ...
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1900 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ...
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Sigerist Society
The British Sigerist Society, named in honour of Henry E. Sigerist was established by Marxist doctors in 1947 and met several times a year until 1955 to discuss the theoretical and social aspects of Medicine from a Marxist point of view. The members included Philip D'Arcy Hart, Martin Roff, Richard Doll and Julian Tudor Hart. Most of them were also members of the Socialist Medical Association which was affiliated to the Labour Party. They discussed the relationship between science and social responsibility and the significance of social class. They advocated salaried and group practice for primary care. Archives of the society are preserved in the Wellcome Library and the Communist Party of Great Britain archive in the Manchester's People's History Museum. There is a separate Sigerist Circle of medical historians based in Baltimore Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most popu ...
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Society For Social Medicine
The Society for Social Medicine (SSM) is the primary organization for researchers in social, community, and public health in the UK and Ireland, founded in London in 1956. The society was renamed the Society for ''Social Medicine and Population Health''. It is affiliated to the European Public Health Association and is a member of the International Epidemiological Association’s European Epidemiology Federation. Aim The main aim of the society is to engage research, development and training in a range of segments such as epidemiology, medical and healthcare for prevention of diseases. Objectives *To advance knowledge for population health. Membership Membership is open to individuals anyone who is interested in the society's aims. There is a nomination process whereby prospective members are put forward for consideration by current members. Applicants who do not any current members can also apply however and their application will be considered. Meetings The Society holds a ...
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Lysosome
A lysosome () is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, apoptosis, cell signaling, and energy metabolism. Lysosomes act as the waste disposal system of the cell by digesting used materials in the cytoplasm, from both inside and outside the cell. Material from outside the cell is taken up through endocytosis, while material from the inside of the cell is digested through autophagy. The sizes of the organelles vary greatly—the larger ones can be more than 10 times the size of the smaller ones. They were discov ...
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