Peter O.D. Pharoah
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Peter O.D. Pharoah
Peter Oswald Derrick Pharoah (May 1934 – 23 October 2021) was a British public health professor at the University of Liverpool from 1979 until 1997. He was known for his work on people with cretinism (as the condition was then known) in Papua New Guinea and cerebral palsy in the United Kingdom. Early life Peter Oswald Derrick Pharoah was born in Ranchi, in the Indian state of Jharkhand, in May 1934. He went to school in Lovedale and Sanawar. In 1948, after his father died, he and his mother moved back to Britain. He studied at Palmer's School in Grays, Essex, before studying at St Mary's Hospital Medical School at Imperial College London, where he met his wife and worked in a team with Sir Roger Bannister, an athlete and neurologist. Medical work He married in 1960, moving three years later to Papua New Guinea to become a medical officer in Rabaul and the district medical officer in Mount Hagen, Wewak and Goroka. When working with villagers in the Jimi Valley, Pharoah r ...
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Public Health
Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the determinants of health of a population and the threats it faces is the basis for public health. The ''public'' can be as small as a handful of people or as large as a village or an entire city; in the case of a pandemic it may encompass several continents. The concept of ''health'' takes into account physical, psychological, and social well-being.What is the WHO definition of health?
from the Preamble to the Constitution of WHO as adopted by the International Health Conference, New York, 19 June - 22 July 1946; signed on ...
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Rabaul
Rabaul () is a township in the East New Britain province of Papua New Guinea, on the island of New Britain. It lies about 600 kilometres to the east of the island of New Guinea. Rabaul was the provincial capital and most important settlement in the province until it was destroyed in 1994 by falling ash from a volcanic eruption in its harbour. During the eruption, ash was sent thousands of metres into the air, and the subsequent rain of ash caused 80% of the buildings in Rabaul to collapse. After the eruption the capital was moved to Kokopo, about away. Rabaul is continually threatened by volcanic activity, because it is on the edge of the Rabaul caldera, a flooded caldera of a large pyroclastic shield. Rabaul was planned and built around the harbour area known as Simpsonhafen (Simpson Harbour) during the German New Guinea administration, which controlled the region between 1884 and formally through 1919. Rabaul was selected as the capital of the German New Guinea administratio ...
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London School Of Hygiene And Tropical Medicine
The London School of Hygiene and Tropical Medicine (LSHTM) is a public research university in Bloomsbury, central London, and a member institution of the University of London that specialises in public health and tropical medicine. The institution was founded in 1899 by Sir Patrick Manson, after a donation from the Indian Parsi philanthropist B. D. Petit. Since its foundation it has become one of the most highly placed institutions in global rankings in the fields of public health and infectious diseases. The annual income of the institution for 2020–21 was £244.2 million, of which £167.6 million was from research grants and contracts, with expenditures totalling £235.2 million during the same period. History Origins (1899–1913) The school was founded on October 2, 1899, by Sir Patrick Manson as the London School of Tropical Medicine after the Parsi philanthropist Bomanjee Dinshaw Petit made a donation of £6,666. It was initially located at ...
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Eradication Of Infectious Diseases
Eradication is the reduction of an infectious disease's prevalence in the global host population to zero. Two infectious diseases have successfully been eradicated: smallpox in humans, and rinderpest in ruminants. There are four ongoing programs, targeting the human diseases poliomyelitis (polio), yaws, dracunculiasis (Guinea worm), and malaria. Five more infectious diseases have been identified as potentially eradicable with current technology by the Carter Center International Task Force for Disease Eradication— measles, mumps, rubella, lymphatic filariasis (elephantiasis) and cysticercosis (pork tapeworm). The concept of disease eradication is sometimes confused with disease ''elimination'', which is the reduction of an infectious disease's prevalence in a regional population to zero, or the reduction of the global prevalence to a negligible amount. Further confusion arises from the use of the term 'eradication' to refer to the total removal of a given pathogen from an ...
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Iodised Salt
Iodised salt ( also spelled iodized salt) is table salt mixed with a minute amount of various salts of the element iodine. The ingestion of iodine prevents iodine deficiency. Worldwide, iodine deficiency affects about two billion people and is the leading preventable cause of intellectual and developmental disabilities. Deficiency also causes thyroid gland problems, including endemic goitre. In many countries, iodine deficiency is a major public health problem that can be cheaply addressed by purposely adding small amounts of iodine to the sodium chloride salt. Iodine is a micronutrient and dietary mineral that is naturally present in the food supply in some regions, especially near sea coasts but is generally quite rare in the Earth's crust since iodine is a so-called heavy element, and abundance of chemical elements generally declines with greater atomic mass. Where natural levels of iodine in the soil are low and the iodine is not taken up by vegetables, iodine added to salt ...
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Pregnancy
Pregnancy is the time during which one or more offspring develops ( gestates) inside a woman's uterus (womb). A multiple pregnancy involves more than one offspring, such as with twins. Pregnancy usually occurs by sexual intercourse, but can also occur through assisted reproductive technology procedures. A pregnancy may end in a live birth, a miscarriage, an induced abortion, or a stillbirth. Childbirth typically occurs around 40 weeks from the start of the last menstrual period (LMP), a span known as the gestational age. This is just over nine months. Counting by fertilization age, the length is about 38 weeks. Pregnancy is "the presence of an implanted human embryo or fetus in the uterus"; implantation occurs on average 8–9 days after fertilization. An '' embryo'' is the term for the developing offspring during the first seven weeks following implantation (i.e. ten weeks' gestational age), after which the term ''fetus'' is used until birth. Signs an ...
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Iodine Deficiency
Iodine deficiency is a lack of the trace element iodine, an essential nutrient in the diet. It may result in metabolic problems such as goiter, sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism, which results in developmental delays and other health problems. Iodine deficiency is an important global health issue, especially for fertile and pregnant women. It is also a preventable cause of intellectual disability. Iodine is an essential dietary mineral for neurodevelopment among children. The thyroid hormones thyroxine and triiodothyronine contain iodine. In areas where there is little iodine in the diet, typically remote inland areas where no marine foods are eaten, iodine deficiency is common. It is also common in mountainous regions of the world where food is grown in iodine-poor soil. Prevention includes adding small amounts of iodine to table salt, a product known as ''iodized salt''. Iodine compound ...
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Congenital Iodine Deficiency Syndrome
Congenital iodine deficiency syndrome is a medical condition present at birth marked by impaired physical and mental development, due to insufficient thyroid hormone (hypothyroidism) often caused by insufficient dietary iodine during pregnancy. It is one cause of underactive thyroid function at birth, called congenital hypothyroidism, historically referred to as cretinism (obsolete). If untreated, it results in impairment of both physical and mental development. Symptoms may include goiter, poor length growth in infants, reduced adult stature, thickened skin, hair loss, enlarged tongue, a protruding abdomen; delayed bone maturation and puberty in children; and mental deterioration, neurological impairment, impeded ovulation, and infertility in adults. In developed countries, thyroid function testing of newborns has assured that in those affected, treatment with the thyroid hormone thyroxine is begun promptly. This screening and treatment have virtually eliminated the consequences o ...
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Age And Female Fertility
Female fertility is affected by age and is a major fertility factor for women. A woman's fertility peaks between the late teens and late-20s, after which it starts to decline slowly. While many sources suggest a more dramatic drop at around 35, this is unclear, since few studies have been conducted since the 19th century. One 2004 study of European women found fertility of the 27–34 and the 35–39 groups had only a four-percent difference. At age 45, a woman starting to try to conceive will have no live birth in 50–80 percent of cases. Menopause, or the cessation of menstrual periods, generally occurs in the 40s and 50s and marks the cessation of fertility, although age-related infertility can occur before then. The relationship between age and female fertility is sometimes referred to as a woman's "biological clock." Quantification of effect The average age of a young woman's first period (menarche) is 12 to 13 (12.5 years in the United States, 12.72 in Canada, 12.9 in t ...
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Iodine
Iodine is a chemical element with the symbol I and atomic number 53. The heaviest of the stable halogens, it exists as a semi-lustrous, non-metallic solid at standard conditions that melts to form a deep violet liquid at , and boils to a violet gas at . The element was discovered by the French chemist Bernard Courtois in 1811 and was named two years later by Joseph Louis Gay-Lussac, after the Ancient Greek 'violet-coloured'. Iodine occurs in many oxidation states, including iodide (I−), iodate (), and the various periodate anions. It is the least abundant of the stable halogens, being the sixty-first most abundant element. As the heaviest essential mineral nutrient, iodine is required for the synthesis of thyroid hormones. Iodine deficiency affects about two billion people and is the leading preventable cause of intellectual disabilities. The dominant producers of iodine today are Chile and Japan. Due to its high atomic number and ease of attachment to organic compound ...
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Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ...
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Jimi Valley
Jimi is a geographical area in the inlands of Papua New Guinea. It is located in the Jimi District of Jiwaka, which was previously a part of the Western Highlands Province until May 2012. It is home to the Jimi Valley. The Jimi District is one of the least developed districts in Papua New Guinea, apart from Green River in Sandaun and Rai Coast in Madang. Its geographical location makes it a remote district of the newly-created Jiwaka province. The district is located in the Jimi Valley, which stretches from the northeast corner of Jiwaka and into Madang Province. Jimi District is almost entirely mountainous and is mostly covered with rainforest, although this forest is disappearing quickly due to peanut cultivation. The District Head Quarter is called Tabibuga, originally called "Tapia Poka". The district is further sub-divided into three small sub-districts; Upper Jimi-Kol, Middle Jimi-Tabibuga and Lower Jimi-Koinambe. The district is named after Jim Taylor, who toured it i ...
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