Peter J Ratcliffe
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Peter J Ratcliffe
Sir Peter John Ratcliffe, FRS, FMedSci (born 14 May 1954) is a British Nobel Laureate physician-scientist who is trained as a nephrologist. He was a practising clinician at the John Radcliffe Hospital, Oxford and Nuffield Professor of Clinical Medicine and head of the Nuffield Department of Clinical Medicine at the University of Oxford from 2004 to 2016. He has been a Fellow of Magdalen College, Oxford since 2004. In 2016 he became Clinical Research Director at the Francis Crick Institute, retaining a position at Oxford as member of the Ludwig Institute of Cancer Research and director of the Target Discovery Institute, University of Oxford. Ratcliffe is best known for his work on cellular reactions to hypoxia, for which he shared the 2019 Nobel Prize in Physiology or Medicine with William Kaelin Jr. and Gregg L. Semenza. Education and training Ratcliffe was born in Lancashire on 14 May 1954, to William Ratcliffe and Alice Margaret Ratcliffe. He attended Lancaster Royal Grammar ...
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Morecambe
Morecambe ( ) is a seaside town and civil parish in the City of Lancaster district in Lancashire, England. It is in Morecambe Bay on the Irish Sea. Name The first use of the name was by John Whitaker in his ''History of Manchester'' (1771), when he refers to the "æstury of Moricambe". It next appears four years later in ''Antiquities of Furness'', where the bay is described as "the Bay of Morecambe". That name is derived from the Roman name ''Moriancabris Æsturis'' shown on maps prepared for them by ''Claudius Ptolemœus'' (Ptolemy) from his original Greek maps. At this distance in time it is impossible to say if the name was originally derived from an earlier language (e.g. Celtic language) or from Greek. The Latin version describes the fourth inlet north from Wales on the west coast of England as Moriancabris Æsturis. Translated, this gives a more accurate description than the present name of Morecambe Bay as the Latin refers to multiple estuaries on a curved sea, not a ...
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Robert J
The name Robert is an ancient Germanic given name, from Proto-Germanic "fame" and "bright" (''Hrōþiberhtaz''). Compare Old Dutch ''Robrecht'' and Old High German ''Hrodebert'' (a compound of '' Hruod'' ( non, Hróðr) "fame, glory, honour, praise, renown" and ''berht'' "bright, light, shining"). It is the second most frequently used given name of ancient Germanic origin. It is also in use as a surname. Another commonly used form of the name is Rupert. After becoming widely used in Continental Europe it entered England in its Old French form ''Robert'', where an Old English cognate form (''Hrēodbēorht'', ''Hrodberht'', ''Hrēodbēorð'', ''Hrœdbœrð'', ''Hrœdberð'', ''Hrōðberχtŕ'') had existed before the Norman Conquest. The feminine version is Roberta. The Italian, Portuguese, and Spanish form is Roberto. Robert is also a common name in many Germanic languages, including English, German, Dutch, Norwegian, Swedish, Scots, Danish, and Icelandic. It can be use ...
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William Kaelin Jr
William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills Wills may refer to: * Will (law) A will or testament is a legal document that expresses a person's (testator) wishes as to how their property ( estate) is to be distributed after their death and as to which person (executor) is to manage the pr ..., Willy, Willie, Bill (given name), Bill, and Billy (name), Billy. A common Irish people, Irish form is Liam. Scottish people, Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play Douglas (play)#Theme and response, ''Douglas''). Female f ...
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Hypoxia (medical)
Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. Hypoxia may be classified as either '' generalized'', affecting the whole body, or ''local'', affecting a region of the body. Although hypoxia is often a pathological condition, variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise.. Hypoxia differs from hypoxemia and anoxemia, in that hypoxia refers to a state in which oxygen present in a tissue or the whole body is insufficient, whereas hypoxemia and anoxemia refer specifically to states that have low or no oxygen in the blood. Hypoxia in which there is complete absence of oxygen supply is referred to as anoxia. Hypoxia can be due to external causes, when the breathing gas is hypoxic, or internal causes, such as reduced effectiveness of gas transfer in the lungs, reduced capacity of the blood to carry oxygen, compromised general ...
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Magdalen College, Oxford
Magdalen College (, ) is a constituent college of the University of Oxford. It was founded in 1458 by William of Waynflete. Today, it is the fourth wealthiest college, with a financial endowment of £332.1 million as of 2019 and one of the strongest academically, setting the record for the highest Norrington Score in 2010 and topping the table twice since then. It is home to several of the university's distinguished chairs, including the Agnelli-Serena Professorship, the Sherardian Professorship, and the four Waynflete Professorships. The large, square Magdalen Tower is an Oxford landmark, and it is a tradition, dating to the days of Henry VII, that the college choir sings from the top of it at 6 a.m. on May Morning. The college stands next to the River Cherwell and the University of Oxford Botanic Garden. Within its grounds are a deer park and Addison's Walk. History Foundation Magdalen College was founded in 1458 by William of Waynflete, Bishop of Winchester a ...
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Nuffield Professor Of Clinical Medicine
The Nuffield Professorship of Clinical Medicine is a chair at the University of Oxford. Created by the endowment of William Morris, 1st Viscount Nuffield, it was established in 1937. The chair is associated with a fellowship of Magdalen College, Oxford. List of Nuffield Professors of Clinical Medicine * 1937–1965: Leslie John Witts * 1965–1974: Paul Bruce Beeson * 1974–1992: Sir David Weatherall * 1992–2002: Sir John Bell * 2004–2016: Sir Peter Ratcliffe * 2019–present: Richard Cornall Richard is a male given name. It originates, via Old French, from Old Frankish and is a compound of the words descending from Proto-Germanic ''*rīk-'' 'ruler, leader, king' and ''*hardu-'' 'strong, brave, hardy', and it therefore means 'strong ... References {{reflist Professorships at the University of Oxford Professorships in medicine ...
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John Radcliffe Hospital
The John Radcliffe Hospital (informally known as the JR) is a large tertiary teaching hospital in Oxford, England. It forms part of the Oxford University Hospitals NHS Foundation Trust and is named after John Radcliffe, an 18th-century physician and Oxford University graduate, who endowed the Radcliffe Infirmary, the main hospital for Oxford from 1770 until 2007. It is the main teaching hospital for Oxford University and Oxford Brookes University, and incorporates the Oxford University Medical School. History The distinctive large white-tiled structure occupies a prominent position on Headington Hill, on the outskirts of Oxford. JR1: This was the initial hospital building, opened in 1972. It houses women's services and neonatology. The second building, JR2, opened in 1979 and is much larger. It contains most of the other specialist services for the region. Other facilities were then added to the site, including the University of Oxford's Centre for Functional Magnetic Reso ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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Nephrologist
Nephrology (from Greek'' nephros'' "kidney", combined with the suffix ''-logy'', "the study of") is a specialty of adult internal medicine and pediatric medicine that concerns the study of the kidneys, specifically normal kidney function (renal physiology) and kidney disease (renal pathophysiology), the preservation of kidney health, and the treatment of kidney disease, from diet and medication to renal replacement therapy ( dialysis and kidney transplantation). The word “renal” is an adjective meaning “relating to the kidneys”, and its roots are French or late Latin. Whereas according to some opinions, "renal" and "nephro" should be replaced with "kidney" in scientific writings such as "kidney medicine" (instead of nephrology) or "kidney replacement therapy", other experts have advocated preserving the use of renal and nephro as appropriate including in "nephrology" and "renal replacement therapy", respectively. Nephrology also studies systemic conditions that affec ...
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Physician-scientist
A physician-scientist is traditionally a holder of a medical degree and a doctor of philosophy also known as an MD-PhD. Compared to other clinicians, physician-scientists invest significant time and professional effort in scientific research and spend correspondingly less time in direct clinical practice with ratios of research to clinical time ranging from 50/50 to 80/20. Physician-scientists are often employed by academic or research institutions where they drive innovation across a wide range of medical specialties and may also use their extensive training to focus their clinical practices on specialized patient populations, such as those with rare genetic diseases or cancers. Although they are a minority of both practicing physicians and active research scientists, physician-scientists are often cited as playing a critical roles in translational medicine and clinical research by adapting biomedical research findings to health care applications. Over time, the term physician sc ...
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Academy Of Medical Sciences
The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its mission is to advance biomedical and health research and its translation into benefits for society. The academy consists of a group of around 1200 Fellows elected from fields across the biomedical sciences. The academy seeks ultimately to advance medical science and improve health by investing in talented researchers, engaging people on health-related issues and providing expert impartial advice. its president is Dame Anne Johnson. History The academy was established in 1998 following the recommendations of a working group chaired by Michael Atiyah, former president of the Royal Society. A single national organisation was formed to support biomedical scientists and clinical academics working together to promote advances in medical science. It is one ...
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ...
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