Pergularia Daemia
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Pergularia Daemia
''Pergularia daemia'', the trellis-vine, is a hispid, perennial vine in the family Asclepiadaceae, with an extensive range in the Old World tropics and subtropics. It has been used traditionally to treat a number of ailments. It is sometimes called ''atufa.'' Range and habitat It occurs from the Malay Peninsula to Burma, India, Sri Lanka, Pakistan, Afghanistan through Arabia and Egypt to central and southern Africa. It is found along roadsides, in woodland or along riparian forest fringes. Description The opposite and broadly ovate to suborbicular leaves are very variable in size, with petioles of varying length. The leaves are almost glabrous above and velvety below. In the northern hemisphere the flowers appear from mid to late winter, and these are carried on lateral cymes. The flower corolla forms a greenish-yellow or dull white tube. The fruit mature after some 13 to 14 months when they release ovate seeds covered with velvety hairs. Phytochemical properties Terpenoids, fl ...
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Limpopo
Limpopo is the northernmost province of South Africa. It is named after the Limpopo River, which forms the province's western and northern borders. The capital and largest city in the province is Polokwane, while the provincial legislature is situated in Lebowakgomo. The province is made up of 3 former homelands of Lebowa, Gazankulu and Venda and the former parts of the Transvaal province. The Limpopo province was established as one of the new nine provinces after South Africa's first democratic election on the 27th of April 1994. The province's name was first "Northern Transvaal", later changed to "Northern Province" on the 28th of June 1995, together with two other provinces. The name was later changed again in 2002 to the Limpopo province. Limpopo is made up of 3 main ethnic groups namely; Pedi people, Tsonga and Venda people. Traditional leaders and chiefs still form a strong backbone of the province's political landscape. Established in terms of the Limpopo House of Tra ...
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Sterol
Sterol is an organic compound with formula , whose molecule is derived from that of gonane by replacement of a hydrogen atom in position 3 by a hydroxyl group. It is therefore an alcohol of gonane. More generally, any compounds that contain the gonane structure, additional functional groups, and/or modified ring systems derived from gonane are called steroids. Therefore, sterols are a subgroup of the steroids. They occur naturally in most eukaryotes, including plants, animals, and fungi, and can also be produced by some bacteria (however likely with different functions). The most familiar type of animal sterol is cholesterol, which is vital to cell membrane structure, and functions as a precursor to fat-soluble vitamins and steroid hormones. While technically alcohols, sterols are classified by biochemists as lipids ( fats in the broader sense of the term). Types Sterols of plants are called '' phytosterols'' and sterols of animals are called ''zoosterols''. The most impo ...
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Afrotropical Realm Flora
The Afrotropical realm is one of Earth's eight biogeographic realms. It includes Africa south of the Sahara Desert, the majority of the Arabian Peninsula, the island of Madagascar, southern Iran and extreme southwestern Pakistan, and the islands of the western Indian Ocean. It was formerly known as the Ethiopian Zone or Ethiopian Region. Major ecological regions Most of the Afrotropic, with the exception of Africa's southern tip, has a tropical climate. A broad belt of deserts, including the Atlantic and Sahara deserts of northern Africa and the Arabian Desert of the Arabian Peninsula, separate the Afrotropic from the Palearctic realm, which includes northern Africa and temperate Eurasia. Sahel and Sudan South of the Sahara, two belts of tropical grassland and savanna run east and west across the continent, from the Atlantic Ocean to the Ethiopian Highlands. Immediately south of the Sahara lies the Sahel belt, a transitional zone of semi-arid short grassland and vachellia s ...
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Danaus Chrysippus
''Danaus chrysippus'', also known as the plain tiger, African queen, or African monarch, is a medium-sized butterfly widespread in Asia, Australia and Africa. It belongs to the Danainae subfamily of the brush-footed butterfly family Nymphalidae. Danainae primarily consume plants in the genus ''Asclepias'', more commonly called milkweed. Milkweed contains toxic compounds, cardenolides, which are often consumed and stored by many butterflies. Because of their emetic properties, the plain tiger is unpalatable to most predators. As a result, its coloration is widely mimicked by other species of butterflies. The plain tiger inhabits a wide variety of habitats, although it is less likely to thrive in jungle-like conditions and is most often found in drier, wide-open areas. ''D. chrysippus'' encompasses three main subspecies: ''D. c. alcippus, D. c. chrysippus,'' and ''D. c. orientis.'' These subspecies are found concentrated in specific regions within the larger range of the entire spe ...
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Anti-inflammatory
Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain. Nonsteroidal anti-inflammatory drugs Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. On its own, COX enzyme synthesizes prostaglandins, creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the inflammation and resulting pain. Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs, even though they presumably share the same mode of action. On the other hand, there are analgesics that are commonly associa ...
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Analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It is typically used to induce cooperation with a medical procedure. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owi ...
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Anti-diabetic Medication
Drugs used in diabetes treat diabetes mellitus by altering the glucose level in the blood. With the exceptions of insulin, most GLP receptor agonists (liraglutide, exenatide, and others), and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral antihyperglycemic agents. There are different classes of anti-diabetic drugs, and their selection depends on the nature of the diabetes, age and situation of the person, as well as other factors. Diabetes mellitus type 1 is a disease caused by the lack of insulin. Insulin must be used in type 1, which must be injected. Diabetes mellitus type 2 is a disease of insulin resistance by cells. Type 2 diabetes mellitus is the most common type of diabetes. Treatments include agents that (1) increase the amount of insulin secreted by the pancreas, (2) increase the sensitivity of target organs to insulin, (3) decrease the rate at which glucose is absorbed from the gastrointestinal tract, and (4) incr ...
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Hepatoprotection
Hepatoprotection or antihepatotoxicity is the ability of a chemical substance to prevent damage to the liver. This is opposite to hepatotoxicity. Hepatoprotective molecules used in emergency medicine * Acetylcysteine is considered the hepatoprotective drug of choice when treating an overdose of acetaminophen/paracetamol. * Silymarin is given intravenously to treat poisoning from Amanita mushrooms according to the Santa Cruz protocol devised by Dr Todd Mitchell at UCSC. Herbs with potentially hepatoprotective constituents * ''Astragalus membranaceus'' * ''Curcuma longa'' * ''Brassica'' * ''Silybum marianum'' * ''Andrographis paniculata ''Andrographis paniculata'', commonly known as creat or green chiretta, is an annual herbaceous plant in the family Acanthaceae, native to India and Sri Lanka. It is widely cultivated in Southern and Southeastern Asia, where it has been believ ...''Andrographis paniculata http://www.stuartxchange.com/Sinta.html References {{Bile and liver ...
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Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the '' Plasmodium'' group. It is spread exclusively through bites of infected '' Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spr ...
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Diarrhoea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and irritable behaviour. This can progress to decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe. Loose but non-watery stools in babies who are exclusively breastfed, however, are normal. The most common cause is an infection of the intestines due to either a virus, bacterium, or parasite—a condition also known as gastroenteritis. These infections are often acquired from food or water that has been contaminated by feces, or directly from another person who is infected. The three types of diarrhea are: short duration watery diarrhea, short duration bloody diarrhea, and persistent diarrhea (lasting more than two weeks, wh ...
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Expectorant
Mucoactive agents are a class of chemical agents that aid in the clearance of mucus or sputum from the upper and lower airways, including the lungs, bronchi, and trachea. Mucoactive drugs include expectorants, mucolytics, mucoregulators, and mucokinetics. These medications are used in the treatment of respiratory diseases that are complicated by the oversecretion or inspissation of mucus. These drugs can be further categorized by their mechanism of action. Mechanism of action Mucoactive agents - expectorants – include mucolytics, secretolytics and mucokinetics (also called secretomotorics) * Mucolytics – thin (reduce the viscosity of) mucus * Secretolytics – increase airway water or the volume of airway secretions * Mucokinetics – increase mucociliary transport (clearance) and transportability of mucus by cough * Mucoregulators – suppress underlying mechanisms of mucus hypersecretion Alternatively, attacking the affinity between secretions and the biological surfaces ...
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Antipyretic
An antipyretic (, from ''anti-'' 'against' and ' 'feverish') is a substance that reduces fever. Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever. Most antipyretic medications have other purposes. The most common antipyretics in the US are usually ibuprofen and aspirin, which are nonsteroidal anti-inflammatory drugs (NSAIDs) used primarily as anti-inflammatories and analgesics (pain relievers), but which also have antipyretic properties; and paracetamol (acetaminophen), an analgesic without anti-inflammatory properties. There is some debate over the appropriate use of such medications, since fever is part of the body's immune response to infection. A study published by the Royal Society claims that fever suppression causes at least 1% more influenza deaths in the United States, or 700 extra deaths per year. Non-pharmacological treatment Bathing or sp ...
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