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Penk (Star Trek)
Penk may refer to: * River Penk * Penk (''Star Trek'') * Proenkephalin or PENK. A name of gene encoding a precursor of enkephalin An enkephalin is a pentapeptide involved in regulating nociception in the body. The enkephalins are termed endogenous ligands, as they are internally derived and bind to the body's opioid receptors. Discovered in 1975, two forms of enkephalin ... and other related peptides. {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
River Penk
The River Penk is a small river flowing through Staffordshire, England. Its course is mainly within South Staffordshire, and it drains most of the northern part of that district, together with some adjoining areas of Cannock Chase, Stafford, Wolverhampton, and Shropshire. It flows into the River Sow, which is a tributary of the River Trent, so its waters flow ultimately into the North Sea via the Humber Estuary. Etymology The name "Penk" is actually a back-formation from the toponym Penkridge. This was understood to mean "ridge by the Penk"; hence the river was assumed to be the Penk. In reality the settlement name is from Celtic roots: ''pen crug'', signifying the crest of a hill, or a main mound or tumulus. From this was derived the name of a Roman fort in the area, ''Pennocrucium'', from which the present town takes its name. Margaret Gelling has proposed a precise location for the mound, now destroyed by ploughing, that gave both the town and the river the names. Course ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Penk (Star Trek)
Penk may refer to: * River Penk * Penk (''Star Trek'') * Proenkephalin or PENK. A name of gene encoding a precursor of enkephalin An enkephalin is a pentapeptide involved in regulating nociception in the body. The enkephalins are termed endogenous ligands, as they are internally derived and bind to the body's opioid receptors. Discovered in 1975, two forms of enkephalin ... and other related peptides. {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proenkephalin
Introduction Proenkephalin (PENK), formerly known as proenkephalin A (since proenkephalin B was renamed prodynorphin), is an endogenous opioid polypeptide hormone which, via proteolyic cleavage, produces the enkephalin peptides etnkephalin, and to a lesser extent, eunkephalin. Upon cleavage, each proenkephalin peptide results in the generation of four copies of etnkephalin, two extended copies of etnkephalin, and one copy of eunkephalin. Contrarily, eunkephalin] is predominantly synthesized from prodynorphin, which produces three copies of it per cleavage, and no copies of etnkephalin. Other endogenous opioid peptides produced by proenkephalin include adrenorphin, amidorphin, BAM-18, BAM-20P, BAM-22P, peptide B, peptide E, and peptide F. Proenkephalin in human diseases Proenkephalin is produced by the medium spiny neurons of the striatum which undergo neurodegeneration in early stages of Huntingtons disease (HD). PENK and related peptides measured in cereb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Precursor (chemistry)
In chemistry, a precursor is a compound that participates in a chemical reaction that produces another compound. In biochemistry, the term "precursor" often refers more specifically to a chemical compound preceding another in a metabolic pathway, such as a protein precursor. Illicit drug precursors In 1988, the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances introduced detailed provisions and requirements relating the control of precursors used to produce drugs of abuse. In Europe the Regulation (EC) No. 273/2004 of the European Parliament and of the Council on drug precursors was adopted on 11 February 2004. ( European law on drug precursors) Illicit explosives precursors On January 15, 2013, the Regulation (EU) No. 98/2013 of the European Parliament and of the Council on the marketing and use of explosives precursors was adopted. The Regulation harmonises rules across Europe on the making available, introduction, possession and u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
