Paul Workman (scientist)
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Paul Workman (scientist)
Paul Workman (born 30 March 1952) is a British scientist noted for his work on the discovery and development of pharmaceutical agents in the field of oncology. He iPresident and CEOof The Institute of Cancer Research In London. Education and early life Workman was born on 30 March 1952 in Workington, Cumbria, England. He was educated at Workington County Grammar School, Cumbria, and completed his BSc degree in Biochemistry at the University of Leicester and his PhD degree in Cancer Pharmacology at the University of Leeds. He later received an Honorary DSc degree from the University of Leicester in 2009. Career and research The early part of his career (1976–90) was spent establishing and leading the Pharmacology and New Drug Development Laboratory at the Medical Research Council's Clinical Oncology Unit at the University of Cambridge, where he developed new treatments to exploit hypoxic cells in solid tumours and elucidated the enzymes involved in the activation of hypo ...
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Workington
Workington is a coastal town and civil parish at the mouth of the River Derwent on the west coast in the Allerdale borough of Cumbria, England. The town was historically in Cumberland. At the 2011 census it had a population of 25,207. Location The town is south-west of Carlisle, north-east of Whitehaven, west of Cockermouth, and south-west of Maryport. History The area around Workington was long a producer of coal and steel. Between 79 and 122 CE, Roman forts, mile-forts and watchtowers were built along the Cumbrian coast,Richard L. M. Byers (1998). ''History of Workington: An Illustrated History from Earliest Times to 1865''. Richard Byers. . as defences against attacks by the Scoti of Ireland and the Caledonii, the most powerful tribe in what is now Scotland. The 16th-century ''Britannia'', written by William Camden, describes ruins of these defences. A Viking sword was discovered at Northside. This is seen to suggest there was a settlement at the river mouth. The ...
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International Union Against Cancer
The Union for International Cancer Control (previously named International Union Against Cancer) or UICC is a non-governmental organisation with some 1,180 member organisations in more than 170 countries. UICC was founded in 1933 and is based in Geneva, Switzerland. Its member organisations feature cancer societies, governmental agencies, treatment and research centres, patient support groups and professional associations. History UICC was established in Paris in 1933 following a proposal at a cancer congress in Madrid to create an international organisation that would "promote the fight against cancer through research, therapy and the development of social activities." The organisation was given the Latin name , hence the acronym UICC, and the first General Assembly took place in Paris on 4 May 1935, with representatives from 67 national cancer organisations and 43 countries. The English name was changed in 2010 to its current name, Union for International Cancer Control so th ...
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English Biologists
English usually refers to: * English language * English people English may also refer to: Peoples, culture, and language * ''English'', an adjective for something of, from, or related to England ** English national identity, an identity and common culture ** English language in England, a variant of the English language spoken in England * English languages (other) * English studies, the study of English language and literature * ''English'', an Amish term for non-Amish, regardless of ethnicity Individuals * English (surname), a list of notable people with the surname ''English'' * People with the given name ** English McConnell (1882–1928), Irish footballer ** English Fisher (1928–2011), American boxing coach ** English Gardner (b. 1992), American track and field sprinter Places United States * English, Indiana, a town * English, Kentucky, an unincorporated community * English, Brazoria County, Texas, an unincorporated community * Engli ...
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Alumni Of The University Of Leeds
This list of University of Leeds people is a selected list of notable past staff and students of the University of Leeds. Students Politics * Kwabena Kwakye Anti, Ghanaian politician * John Battle, former Labour Member of Parliament for Leeds West (English, 1976) * Irwin Bellow, Baron Bellwin, former Conservative Minister of State for the Environment (LLB in Law) * Sir Bracewell Smith, businessman, Conservative Member of Parliament (1932–45) and Lord Mayor of London (1946). * Alan Campbell, Labour Member of Parliament for Tynemouth and former Government Whip ( PGCE) *Mark Collett, former chairman of the Young BNP, the youth division of the British National Party; Director of Publicity for the Party before being suspended from the party in early April 2010 (Business Economics, 2002) *Nambaryn Enkhbayar, former President of Mongolia (2000-2004) (exchange student, 1986) * José Ángel Gurría, economist, secretary general of the Organisation for Economic Co-operation and Develo ...
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Alumni Of The University Of Leicester
Alumni (singular: alumnus (masculine) or alumna (feminine)) are former students of a school, college, or university who have either attended or graduated in some fashion from the institution. The feminine plural alumnae is sometimes used for groups of women. The word is Latin and means "one who is being (or has been) nourished". The term is not synonymous with "graduate"; one can be an alumnus without graduating (Burt Reynolds, alumnus but not graduate of Florida State, is an example). The term is sometimes used to refer to a former employee or member of an organization, contributor, or inmate. Etymology The Latin noun ''alumnus'' means "foster son" or "pupil". It is derived from PIE ''*h₂el-'' (grow, nourish), and it is a variant of the Latin verb ''alere'' "to nourish".Merriam-Webster: alumnus
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Separate, but from the s ...
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People From Workington
A person (plural, : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal obligation, legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its us ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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1952 Births
Year 195 ( CXCV) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Scrapula and Clemens (or, less frequently, year 948 ''Ab urbe condita''). The denomination 195 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus has the Roman Senate deify the previous emperor Commodus, in an attempt to gain favor with the family of Marcus Aurelius. * King Vologases V and other eastern princes support the claims of Pescennius Niger. The Roman province of Mesopotamia rises in revolt with Parthian support. Severus marches to Mesopotamia to battle the Parthians. * The Roman province of Syria is divided and the role of Antioch is diminished. The Romans annexed the Syrian cities of Edessa and Nisibis. Severus re-establish his h ...
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Royal Society Of Chemistry
The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Royal Institute of Chemistry, the Faraday Society, and the Society for Analytical Chemistry with a new Royal Charter and the dual role of learned society and professional body. At its inception, the Society had a combined membership of 34,000 in the UK and a further 8,000 abroad. The headquarters of the Society are at Burlington House, Piccadilly, London. It also has offices in Thomas Graham House in Cambridge (named after Thomas Graham (chemist), Thomas Graham, the first president of the Chemical Society) where ''RSC Publishing'' is based. The Society has offices in the United States, on the campuses of The University of Pennsylvania and Drexel University, at the University City Science Center in Philadelphia, Pennsylvania, in both Beijing a ...
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Current Cancer Drug Targets
''Current Cancer Drug Targets'' is a peer-reviewed medical journal published by Bentham Science Publishers. The editor-in-chief is Ruiwen Zhang ( UH Drug Discovery Institute). The journal covers research on contemporary molecular drug targets involved in cancer, including medicinal chemistry, pharmacology, molecular biology, genomics, and biochemistry. ''Current Cancer Drug Targets'' publishes original research reports, review papers, and rapid communications ("letters"). Abstracting and indexing ''Current Cancer Drug Targets'' is abstracted and indexed in: * Chemical Abstracts Service/CASSI * EMBASE *EMBiology *MEDLINE * Science Citation Index Expanded *Scopus According to the ''Journal Citation Reports'', the journal has a 2019 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given jo ...
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Hsp90
Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation. It also stabilizes a number of proteins required for tumor growth, which is why Hsp90 inhibitors are investigated as anti-cancer drugs. Heat shock proteins, as a class, are among the most highly expressed cellular proteins across all species. As their name implies, heat shock proteins protect cells when stressed by elevated temperatures. They account for 1–2% of total protein in unstressed cells. However, when cells are heated, the fraction of heat shock proteins increases to 4–6% of cellular proteins. Heat shock protein 90 (Hsp90) is one of the most common of the heat-related proteins. The "90" comes from the fact that it has a mass of roughly 90 kilodaltons. A 90 kDa protein is considered fairly large for a non-fibrous protein. Hsp90 is found in bacteria and all branches of eukarya ...
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