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Paul Eston Lacy
Paul Eston Lacy (February 7, 1924 – February 15, 2005) was an anatomist and experimentalist and one of the world’s leading diabetes mellitus researchers. He is often credited as the originator of islet transplantation. Education Lacy was born in Trinway, Ohio in February, 1924. He was educated at the Ohio State University in Columbus, Ohio, both as an undergraduate and a medical student, obtaining B.S. and M.D. degrees in 1944 and 1948, respectively. From there Lacy matriculated to the Mayo Clinic and Mayo Foundation in Rochester, Minnesota, for graduate work in anatomy and experimental pathology. He was awarded a Ph.D. in that discipline by the University of Minnesota in 1955. Career In 1955, Lacy was appointed assistant professor in the Department of Anatomy at Washington University School of Medicine, St. Louis, Missouri. He undertook research into the characterization of endocrine cells in the pancreas, using ultrastructural and fluorescent-antibody-labeling method ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trinway, Ohio
Trinway is an unincorporated community and census-designated place in northern Cass Township, Muskingum County, Ohio, United States, in the east-central part of the state. The village is 52 miles east of the state capital of Columbus and near the town of Dresden. Trinway is a rural community of mostly residential architecture. History The community was originally known as "Dresden Junction", as it was the point where the Cincinnati and Muskingum Valley Railroad met the Stuebenville and Indiana Railroad (which later became part of the Pittsburgh, Cincinnati, Chicago and St. Louis Railroad). It was also the site of the first railroad station for the nearby village of Dresden. Historic structures There are several buildings of special historic interest in Trinway, including: *The old Trinway School (Built 1878, located at 12750 2nd Avenue, Trinway) *The Trinway Methodist Church (Built 1868) *The Cochran Mansion (Built 1862, located at 12635 Main Street, Trinway) *The Prospect P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beta Cells
Beta cells (β-cells) are a type of cell found in pancreatic islets that synthesize and secrete insulin and amylin. Beta cells make up 50–70% of the cells in human islets. In patients with Type 1 diabetes, beta-cell mass and function are diminished, leading to insufficient insulin secretion and hyperglycemia. Function The primary function of a beta cell is to produce and release insulin and amylin. Both are hormones which reduce blood glucose levels by different mechanisms. Beta cells can respond quickly to spikes in blood glucose concentrations by secreting some of their stored insulin and amylin while simultaneously producing more. Primary cilia on beta cells regulate their function and energy metabolism. Cilia deletion can lead to islet dysfunction and type 2 diabetes. Insulin synthesis Beta cells are the only site of insulin synthesis in mammals. As glucose stimulates insulin secretion, it simultaneously increases proinsulin biosynthesis, mainly through translational cont ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Minnesota Alumni
A university () is an educational institution, institution of higher education, higher (or Tertiary education, tertiary) education and research which awards academic degrees in several Discipline (academia), academic disciplines. Universities typically offer both undergraduate education, undergraduate and postgraduate education, postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2005 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1924 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Diabetologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * Ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Anatomists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zanesville, Ohio
Zanesville is a city in and the county seat of Muskingum County, Ohio, United States. It is located east of Columbus and had a population of 24,765 as of the 2020 census, down from 25,487 as of the 2010 census. Historically the state capital of Ohio, Zanesville anchors the Zanesville micropolitan statistical area (population 86,183), and is part of the greater Columbus-Marion-Zanesville combined statistical area. History Zanesville was named after Ebenezer Zane (1747–1811), who had blazed Zane's Trace, a pioneer trail from Wheeling, Virginia (now in West Virginia) to Maysville, Kentucky through present-day Ohio. In 1797, he remitted land as payment to his son-in-law, John McIntire (1759–1815), at the point where Zane's Trace met the Muskingum River. With the assistance of Zane, McIntire platted the town, opened an inn and ferry by 1799. In 1801, Zanesville was officially renamed, formerly Westbourne, the chosen name for the settlement by Zane. From 1810 to 1812, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Usual Interstitial Pneumonia
Usual interstitial pneumonia (UIP) is a form of lung disease characterized by progressive scarring of both lungs. The scarring (fibrosis) involves the pulmonary interstitium (the supporting framework of the lung). UIP is thus classified as a form of interstitial lung disease. Terminology The term "usual" refers to the fact that UIP is the most common form of interstitial fibrosis. "Pneumonia" indicates "lung abnormality", which includes fibrosis and inflammation. A term previously used for UIP in the British literature is cryptogenic fibrosing alveolitis (CFA), a term that has fallen out of favor since the basic underlying pathology is now thought to be fibrosis, not inflammation. The term usual interstitial pneumonitis (UIP) has also often been used, but again, the ''-itis'' part of that name may overemphasize inflammation. Signs and symptoms The typical symptoms of UIP are progressive shortness of breath and cough for a period of months. In some patients, UIP is diagnosed only ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emil Unanue
Emil Raphael Unanue (September 13, 1934 – December 16, 2022) was a Cuban-American immunologist and Paul & Ellen Lacy Professor Emeritus at Washington University School of Medicine. He is a member of the National Academy of Sciences, the American Academy of Arts and Sciences and the Institute of Medicine. He previously served as chair of the National Academy of Sciences Section of Microbiology and Immunology. Area of expertise Unanue initiated a field of study known as antigen presentation; it is critical to the development of vaccines and underlies an understanding of microbial immunity and autoimmune diseases. In the late 1970s, it was recognized that T lymphocytes could not recognize antigen directly and instead required an interaction with another specialized cell known as the Antigen-presenting cell. Nobel Prize winners, Rolf Zinkernagel and Peter C. Doherty showed that this recognition also required the antigen-presenting cell to be from the same genetic background as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lauren Ackerman
Lauren Vedder Ackerman (March 12, 1905 – July 27, 1993) was an American physician and pathologist, who championed the subspecialty of surgical pathology in the mid-20th century. Early life Ackerman was born in March 1905 in Auburn, New York, to Bertha (née Vedder) and John Ackerman. Both of his parents were college graduates. His father was a civil and mechanical engineer, who later became city manager of Watertown, New York. Despite growing up in a learned family environment, Lauren was an indifferent student with mediocre grades. After high school graduation in 1923 Ackerman began his college studies at St. Lawrence University (Canton, New York), later transferring to, and graduating from, Hamilton College ( Clinton, New York) in 1927 with a B.S. degree in engineering. He worked for the next year in that profession, but then decided to pursue a medical career. Education Lauren was accepted to the University of Rochester School of Medicine (Rochester, New York), then a ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leo Loeb
Leo Loeb (September 21, 1869 – December 28, 1959), was a German-American physician, educator, and experimental pathologist. Early life Loeb, son of a Jewish family from the German Eifel region, was born in 1869 in Mayen, Prussia. He was orphaned as a child and grew up in the care of an uncle. Because of ill health, Leo was educated in schools that were located in German "spa" towns. As a teenager, he enrolled at the University of Heidelberg, but his tenure there was short. Indeed, over the succeeding couple of years, he spent only brief periods at several universities, in Berlin, Freiburg, and Basel, unable to focus his interests. Finally, in 1890, Loeb entered the University of Zurich Medical School. This time he remained in place, except for external sojourns to Edinburgh, London, and the United States for external clinical experiences. Leo received his M.D. in 1897. For his senior thesis, he had done research on skin transplantation in animals; that experience, combined with t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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