Pasko Rakic
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Pasko Rakic
Pasko Rakic ( hr, Paško Rakić, ) is a Yugoslav-born American neuroscientist, who presently works in the Yale School of Medicine Department of Neuroscience in New Haven, Connecticut. His main research interest is in the development and evolution of the human brain. He was the founder and served as Chairman of the Department of Neurobiology at Yale, and was founder and Director of the Kavli Institute for Neuroscience. He is best known for elucidating the mechanisms involved in development and evolution of the cerebral cortex. In 2008, Rakic shared the inaugural Kavli Prize in Neuroscience. He is currently the Dorys McConell Duberg Professor of Neuroscience, leads an active research laboratory, and serves on Advisory Boards and Scientific Councils of a number of Institutions and Research Foundations. Early life and education Rakic was born on May 15, 1933, in Ruma (formerly Kingdom of Yugoslavia). His father, Toma Rakić, was Croatian, originally from Pula (Istria, at that time ...
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ...
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Society For Neuroscience
The Society for Neuroscience (SfN) is a professional society, headquartered in Washington, DC, for basic scientists and physicians around the world whose research is focused on the study of the brain and nervous system. It is especially well known for its annual meeting, consistently one of the largest scientific conferences in the world. History SfN was founded in 1969 by Ralph W. Gerard and, at nearly 37,000 members, has grown to be the largest neuroscience society in the world. The stated mission of the society is to: #Advance the understanding of the brain and the nervous system. #Provide professional development activities, information, and educational resources. #Promote public information and general education about science and neuroscience. #Inform legislators and other policy makers about the implications of research for public policy, societal benefit, and continued scientific progress. Annual meeting The Society holds an annual meeting that is attended by scien ...
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1933 Births
Events January * January 11 – Sir Charles Kingsford Smith makes the first commercial flight between Australia and New Zealand. * January 17 – The United States Congress votes in favour of Philippines independence, against the wishes of U.S. President Herbert Hoover. * January 28 – "Pakistan Declaration": Choudhry Rahmat Ali publishes (in Cambridge, UK) a pamphlet entitled ''Now or Never; Are We to Live or Perish Forever?'', in which he calls for the creation of a Muslim state in northwest India that he calls " Pakstan"; this influences the Pakistan Movement. * January 30 ** National Socialist German Workers Party leader Adolf Hitler is appointed Chancellor of Germany by President of Germany Paul von Hindenburg. ** Édouard Daladier forms a government in France in succession to Joseph Paul-Boncour. He is succeeded on October 26 by Albert Sarraut and on November 26 by Camille Chautemps. February * February 1 – Adolf Hitler gives his "Proclamation to ...
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Patricia Goldman-Rakic
Patricia Goldman-Rakic ( ; née Shoer, April 22, 1937 – July 31, 2003) was an American professor of neuroscience, neurology, psychiatry and psychology at Yale University School of Medicine. She pioneered multidisciplinary research of the prefrontal cortex and working memory. Early life and education Patricia Shoer was born in Salem, Massachusetts. Her father, Irving Shoer, was the son of Latvian immigrants and her mother, Jenny Pearl, was a Russian immigrant. She grew up in Peabody, Massachusetts and attended Peabody High School. Goldman-Rakic earned her bachelor's degree cum laude in neurobiology from Vassar in 1959, and her doctorate from the University of California at Los Angeles in experimental Developmental Psychology in 1963."Patricia Goldman-Rakic", Newsmakers, Issue 4. Gale Group, 2002. Reproduced in Biography Resource Center. Farmington Hills, Mich.: Thomson Gale. 2007. http://galenet.galegroup.com/servlet/BioRC After postdoctoral positions at UCLA and New Yor ...
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Bristol-Myers Squibb Award
Between 1977 and 2006, the Bristol-Myers Squibb Foundation presented annual awards of US$50,000 to scientists for distinguished achievements in fields such as cancer, infectious disease, neuroscience, nutrition, and cardiovascular disease. The recipients of these awards were selected by pre-eminent members of each field and past award recipients. Bristol-Myers Squibb had no role in determining the recipients of the awards. Bristol-Myers Squibb Award for Distinguished Achievement in Cancer Research Bristol-Myers Squibb Award for Distinguished Achievement in Nutrition Research Bristol-Myers Squibb Award for Distinguished Achievement in Neuroscience Research Bristol-Myers Squibb Award for Distinguished Achievement in Infectious Diseases Research Bristol-Myers Squibb Award for Distinguished Achievement in Cardiovascular Research Bristol-Myers Squibb Award for Distinguished Achievement in Metabolic Diseases Research Bristol-Myers Squibb Award for D ...
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International Prize (Fyssen Foundation)
The International Prize (French: ''Prix International'') of the Fyssen Foundation is a science award that has been given annually since 1980 to a scientist who has conducted distinguished research in the areas supported by the foundation such as ethology, palaeontology, archaeology, anthropology, psychology, epistemology, logic Logic is the study of correct reasoning. It includes both formal and informal logic. Formal logic is the science of deductively valid inferences or of logical truths. It is a formal science investigating how conclusions follow from premise ... and the neurosciences. List of awardees The following persons have received the International Prize: References {{Reflist French science and technology awards ...
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Karl Spencer Lashley Award
The Karl Spencer Lashley Award is awarded by The American Philosophical Society as a recognition of research on the integrative neuroscience of behavior. The award was established in 1957 by a gift from Dr. Karl Spencer Lashley. Recipients * 2022 Nicholas Spitzer * 2021 Patricia K. Kuhl «in recognition of her fundamental discoveries concerning how human infants acquire language, and how brain structure and activity changes during language learning in both monolingual and bilingual children» * 2020 Winrich Freiwald and Doris Tsao - "In recognition of their ground-breaking discoveries of primate cortical areas that selectively encode visual information about faces, the computational principles underlying face encoding in these areas, and the implications of these discoveries for social cognition." *2019 Wolfram Schultz * 2018 Catherine Dulac - "In recognition of her incisive studies of the molecular and circuit basis of instinctive behaviors mediated through olfactory sys ...
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Protomap (neuroscience)
The Protomap is a primordial molecular map of the functional areas of the mammalian cerebral cortex during early embryonic development, at a stage when neural stem cells are still the dominant cell type. The protomap is a feature of the ventricular zone, which contains the principal cortical progenitor cells, known as radial glial cells. Through a process called 'cortical patterning', the protomap is patterned by a system of signaling centers in the embryo, which provide positional information and cell fate instructions. These early genetic instructions set in motion a development and maturation process that gives rise to the mature functional areas of the cortex, for example the visual, somatosensory, and motor areas. The term protomap was coined by Pasko Rakic. The ''protomap hypothesis'' was opposed by the ''protocortex hypothesis'', which proposes that cortical proto-areas initially have the same potential, and that regionalization in large part is controlled by external infl ...
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Radiolabel
A radioactive tracer, radiotracer, or radioactive label is a chemical compound in which one or more atoms have been replaced by a radionuclide so by virtue of its radioactive decay it can be used to explore the mechanism of chemical reactions by tracing the path that the radioisotope follows from reactants to products. Radiolabeling or radiotracing is thus the radioactive form of isotopic labeling. In biological contexts, use of radioisotope tracers are sometimes called radioisotope feeding experiments. Radioisotopes of hydrogen, carbon, phosphorus, sulfur, and iodine have been used extensively to trace the path of biochemical reactions. A radioactive tracer can also be used to track the distribution of a substance within a natural system such as a cell or tissue, or as a flow tracer to track fluid flow. Radioactive tracers are also used to determine the location of fractures created by hydraulic fracturing in natural gas production.Reis, John C. (1976). ''Environmental Control i ...
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Conception (biology)
Fertilisation or fertilization (see American and British English spelling differences#-ise, -ize (-isation, -ization), spelling differences), also known as generative fertilisation, syngamy and impregnation, is the fusion of gametes to give rise to a new individual organism or offspring and initiate its development. Processes such as insemination or pollination which happen before the fusion of gametes are also sometimes informally called fertilisation. The cycle of fertilisation and development of new individuals is called sexual reproduction. During double fertilisation in angiosperms the haploid male gamete combines with two haploid polar nuclei to form a triploid primary endosperm nucleus by the process of vegetative fertilisation. History In Antiquity, Aristotle conceived the formation of new individuals through fusion of male and female fluids, with form and function emerging gradually, in a mode called by him as Epigenesis (biology), epigenetic. In 1784, Spallanzani ...
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Fetus
A fetus or foetus (; plural fetuses, feti, foetuses, or foeti) is the unborn offspring that develops from an animal embryo. Following embryonic development the fetal stage of development takes place. In human prenatal development, fetal development begins from the ninth week after fertilization (or eleventh week gestational age) and continues until birth. Prenatal development is a continuum, with no clear defining feature distinguishing an embryo from a fetus. However, a fetus is characterized by the presence of all the major body organs, though they will not yet be fully developed and functional and some not yet situated in their final anatomical location. Etymology The word ''fetus'' (plural ''fetuses'' or '' feti'') is related to the Latin '' fētus'' ("offspring", "bringing forth", "hatching of young") and the Greek "φυτώ" to plant. The word "fetus" was used by Ovid in Metamorphoses, book 1, line 104. The predominant British, Irish, and Commonwealth spelling is '' ...
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Thymidine
Thymidine (symbol dT or dThd), also known as deoxythymidine, deoxyribosylthymine, or thymine deoxyriboside, is a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in G1/early S phase. The prefix deoxy- is often left out since there are no precursors of thymine nucleotides involved in RNA synthesis. Before the boom in thymidine use caused by the need for thymidine in the production of the antiretroviral drug azidothymidine (AZT), much of the world's thymidine production came from herring sperm. Thymidine occurs almost exclusively in DNA but it also occurs in the T-loop of tRNA. Structure and properties In its composition, deoxythymidine is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base thymine. Deoxythymidine can be phosphorylated with one, two or three phosphoric acid groups, creating dTMP (deoxythymidine ...
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