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Parainfluenza Hemagglutinin-neuraminidase
Parainfluenza hemagglutinin-neuraminidase is a type of hemagglutinin-neuraminidase produced by parainfluenza Human parainfluenza viruses (HPIVs) are the viruses that cause human parainfluenza. HPIVs are a paraphyletic group of four distinct single-stranded RNA viruses belonging to the ''Paramyxoviridae'' family. These viruses are closely associated with .... References Viral structural proteins {{virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemagglutinin-neuraminidase
Hemagglutinin-neuraminidase refers to a single viral protein that has both hemagglutinin and (endo) neuraminidase activity. This is in contrast to the proteins found in influenza, where both functions exist but in two separate proteins. Its neuraminidase domain has the CAZy designation glycoside hydrolase family 83 (GH83). It does show a structural similarity to influenza viral neuraminidase and has a six-bladed beta-propeller structure. This Pfam entry also matches measles hemagglutinin (cd15467), which has a "dead" neuraminidase part repurposed as a receptor binding site. Hemagglutinin-neuraminidase allows the virus to stick to a potential host cell, and cut itself loose if necessary. Hemagglutinin-neuraminidase can be found in a variety of paramyxoviruses including mumps virus, human parainfluenza virus 3, and the avian pathogen Newcastle disease virus. Types include: * Mumps hemagglutinin-neuraminidase * Parainfluenza hemagglutinin-neuraminidase Parainfluenza hemagglutin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parainfluenza
Human parainfluenza viruses (HPIVs) are the viruses that cause human parainfluenza. HPIVs are a paraphyletic group of four distinct single-stranded RNA viruses belonging to the ''Paramyxoviridae'' family. These viruses are closely associated with both human and veterinary disease. Virions are approximately 150–250 nm in size and contain negative sense RNA with a genome encompassing about 15,000 nucleotides. The viruses can be detected via cell culture, immunofluorescent microscopy, and PCR. HPIVs remain the second main cause of hospitalisation in children under 5 years of age for a respiratory illness (only Respiratory syncytial virus (RSV) causes more respiratory hospitalisations for this age group). Classification The first HPIV was discovered in the late 1950s. The taxonomic division is broadly based on antigenic and genetic characteristics, forming four major serotypes or clades, which today are considered distinct viruses. These include: HPIVs belong to two gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
