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SDH
SDH may refer to: Science, medicine and technology * Serine dehydratase, an enzyme * L-sorbose 1-dehydrogenase, an enzyme * Succinate dehydrogenase, an enzyme * Shubnikov–de Haas effect * Social Determinants of Health, economic and social conditions of the population. * Sorbitol dehydrogenase * Subdural hematoma or subdural hemorrhage, brain bleeding * Succinate dehydrogenase, in SDHA, SDHB, SDHC, SDHD * Synchronous digital hierarchy, in telecommunications Organizations and places * St David's Hall * Social Democrats of Croatia * Society for Digital Humanities * Sonia, Daniel and Hecker Co. * Sydney Dental Hospital Transportation * Sudbury Hill Harrow railway station Sudbury Hill Harrow railway station is a National Rail station on the Chiltern Main Line in the London Borough of Harrow in northwest London. The station is served by Chiltern Railways trains from Marylebone towards High Wycombe and Birmingha ..., England, National Rail station code Other * The ISO 63 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SDHC
Secure Digital, officially abbreviated as SD, is a proprietary non-volatile flash memory card format developed by the SD Association (SDA) for use in portable devices. The standard was introduced in August 1999 by joint efforts between SanDisk, Panasonic (Matsushita) and Toshiba as an improvement over MultiMediaCards (MMCs), and has become the industry standard. The three companies formed SD-3C, LLC, a company that licenses and enforces intellectual property rights associated with SD memory cards and SD host and ancillary products. The companies also formed the SD Association (SDA), a non-profit organization, in January 2000 to promote and create SD Card standards. SDA today has about 1,000 member companies. The SDA uses several trademarked logos owned and licensed by SD-3C to enforce compliance with its specifications and assure users of compatibility. History 1999–2003: Creation In 1999, SanDisk, Panasonic (Matsushita), and Toshiba agreed to develop and market the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synchronous Digital Hierarchy
Synchronous optical networking (SONET) and synchronous digital hierarchy (SDH) are standardized protocols that transfer multiple digital bit streams synchronously over optical fiber using lasers or highly coherent light from light-emitting diodes (LEDs). At low transmission rates data can also be transferred via an electrical interface. The method was developed to replace the plesiochronous digital hierarchy (PDH) system for transporting large amounts of telephone calls and data traffic over the same fiber without the problems of synchronization. SONET and SDH, which are essentially the same, were originally designed to transport circuit mode communications (e.g., DS1, DS3) from a variety of different sources, but they were primarily designed to support real-time, uncompressed, circuit-switched voice encoded in PCM format. The primary difficulty in doing this prior to SONET/SDH was that the synchronization sources of these various circuits were different. This meant that each ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SDHB
Succinate dehydrogenase biquinoneiron-sulfur subunit, mitochondrial (SDHB) also known as iron-sulfur subunit of complex II (Ip) is a protein that in humans is encoded by the ''SDHB'' gene. The succinate dehydrogenase (also called SDH or Complex II) protein complex catalyzes the oxidation of succinate (succinate + ubiquinone => fumarate + ubiquinol). SDHB is one of four protein subunits forming succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the hydrophilic, catalytic end of the SDH complex. It is also connected to the SDHC/SDHD subunits on the hydrophobic end of the complex anchored in the mitochondrial membrane. The subunit is an iron-sulfur protein with three iron-sulfur clusters. It weighs 30 kDa. Structure The gene that codes for the SDHB protein is nuclear, not mitochondrial DNA. However, the expressed protein is located in the inner membrane of the mitochondria. The location of the gene in humans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SDHD
Succinate dehydrogenase biquinonecytochrome b small subunit, mitochondrial (CybS), also known as succinate dehydrogenase complex subunit D (SDHD), is a protein that in humans is encoded by the ''SDHD'' gene. Names previously used for SDHD were PGL and PGL1. Succinate dehydrogenase is an important enzyme in both the citric acid cycle and the electron transport chain. Structure The SDHD gene is located on chromosome 11 at locus 11q23 and it spans 8,978 base pairs. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. The SDHD gene produces a 17 kDa protein composed of 159 amino acids. The SDHD protein is one of the two integral transmembrane subunits anchoring the four-subunit succinate dehydrogenase (Complex II) protein complex to the matrix side of the mitochondrial inner membrane. The other transmembrane subunit is SDHC. The SDHC/SDHD dimer is connected to the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit. Functi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Succinate Dehydrogenase
Succinate dehydrogenase (SDH) or succinate-coenzyme Q reductase (SQR) or respiratory complex II is an enzyme complex, found in many bacterial cells and in the inner mitochondrial membrane of eukaryotes. It is the only enzyme that participates in both the citric acid cycle and the electron transport chain. Histochemical analysis showing high succinate dehydrogenase in muscle demonstrates high mitochondrial content and high oxidative potential. In step 6 of the citric acid cycle, SQR catalyzes the oxidation of succinate to fumarate with the reduction of ubiquinone to ubiquinol. This occurs in the inner mitochondrial membrane by coupling the two reactions together. Structure Subunits Mitochondrial and many bacterial SQRs are composed of four structurally different subunits: two hydrophilic and two hydrophobic. The first two subunits, a flavoprotein (SdhA) and an iron-sulfur protein (SdhB), form a hydrophilic head where enzymatic activity of the complex takes place. Sdh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SDHA
Succinate dehydrogenase complex, subunit A, flavoprotein variant is a protein that in humans is encoded by the ''SDHA'' gene. This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. SDHA contains the FAD binding site where succinate is deprotonated and converted to fumarate. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Structure The ''SDHA'' gene is located on the p arm of chromosome 5 at locus 15 and is composed of 16 exons. The SDHA protein encoded by this gene is 664 amino acids long and weighs 72.7 kDA. SDHA protein has four subdomains, including capping ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serine Dehydratase
Serine dehydratase or L-serine ammonia lyase (SDH) is in the β-family of pyridoxal phosphate-dependent (PLP) enzymes. SDH is found widely in nature, but its structural and properties vary among species. SDH is found in yeast, bacteria, and the cytoplasm of mammalian hepatocytes. SDH catalyzes is the deamination of L-serine to yield pyruvate, with the release of ammonia. This enzyme has one substrate, L-serine, and two products, pyruvate and NH3, and uses one cofactor, pyridoxal phosphate (PLP). The enzyme's main role is in gluconeogenesis in the liver's cytoplasm. Nomenclature Serine Dehydratase is also known as: * L-serine ammonia-lyase * Serine deaminase * L-hydroxyaminoacid dehydratase * L-serine deaminase * L-serine dehydratase * L-serine hydro-lyase Structure The holoenzyme SDH contains 319 residues, one PLP cofactor molecule. The overall fold of the monomer is very similar to that of other PLP-dependent enzymes of the Beta-family. The enzyme contains a large c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sorbitol Dehydrogenase
Sorbitol dehydrogenase (or SDH) is a cytosolic enzyme. In humans this protein is encoded by the ''SORD'' gene. Sorbitol dehydrogenase is an enzyme in carbohydrate metabolism converting sorbitol, the sugar alcohol form of glucose, into fructose. Together with aldose reductase, it provides a way for the body to produce fructose from glucose without using ATP. Sorbitol dehydrogenase uses NAD+ as a cofactor; its reaction is sorbitol + NAD+ --> fructose + NADH + H+. A zinc ion is also involved in catalysis. Organs that use it most frequently include the liver and seminal vesicle; it is found in various organisms from bacteria to humans. A secondary use is the metabolism of dietary sorbitol, though sorbitol is known not to be absorbed as well in the intestine as its related compounds glucose and fructose, and is usually found in quite small amounts in the diet (except when used as an artificial sweetener). Structure The structure of human sorbitol dehydrogenase was determine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Society For Digital Humanities
The Canadian Society for Digital Humanities is a Canadian scholarly association. Its full name is Society for Digital Humanities/''Société canadienne des humanités numériques'' (CSDH-SCHN). The CSDH-SCHN was founded as the COCH/COSH or Consortium for Computers in the Humanities/ ''Consortium pour ordinateurs en sciences humaines'' in 1986. The organization changed its name to the Society for Digital Humanities/Société pour l'étude des médias interactifs (SDH/SEMI), but became CSDH-SCHN after 2007, when it was enfranchised by the Alliance of Digital Humanities Organizations. The CSDH-SCHN meets every year as part of the Congress of the Social Sciences and Humanities organized by the Canadian Federation for the Humanities and Social Sciences. Our objective is to draw together humanists who are engaged in digital and computer-assisted research, teaching, and creation. The society fosters work in the digital humanities in Canada's two official languages, and champions interact ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sydney Dental Hospital
Sydney Dental Hospital (SDH) is in Sydney, New South Wales, Australia, in Surry Hills, between Chalmers Street and Elizabeth Street opposite the entrance to Central railway station. SDH provides both specialist treatment and general dental services. * Specialist treatment is provided to people referred statewide for Paediatric Dentistry, Orthodontics, Periodontics, Oral Surgery and Diagnostic Imaging, Prosthodontics, Endodontics, Oral Pathology, Oral and Maxillo-facial Surgery and Implantology services. The Special Care Dental Unit provides care to those with chronic mental health conditions and the elderly. * General dental care is available without a referral to children (under 18 years old) and to certain vulnerable groups of adults, including indigenous Australians and those who meet certain government social security stipulations. General dental treatment is also provided by dental students of the University of Sydney within the Department of Clinical Dentistry & Si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subdural Hematoma
A subdural hematoma (SDH) is a type of bleeding in which a Hematoma, collection of blood—usually but not always associated with a traumatic brain injury—gathers between the inner layer of the dura mater and the arachnoid mater of the meninges surrounding the brain. It usually results from tears in bridging veins that cross the subdural space. Subdural hematomas may cause an increase in the intracranial pressure, pressure inside the skull, which in turn can cause compression of and damage to delicate brain tissue. Acute subdural hematomas are often life-threatening. Chronic subdural hematomas have a better prognosis if properly managed. In contrast, epidural hematomas are usually caused by tears in arteries, resulting in a build-up of blood between the dura mater and the skull. The third type of brain hemorrhage, known as a subarachnoid hemorrhage, causes bleeding into the subarachnoid space between the arachnoid mater and the pia mater. __TOC__ Signs and symptoms The sympt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Social Determinants Of Health
The social determinants of health (SDOH) are the economic and social conditions that influence individual and group differences in health status. They are the health promoting factors found in one's living and working conditions (such as the distribution of income, wealth, influence, and power), rather than individual risk factors (such as behavioral risk factors or genetics) that influence the risk for a disease, or vulnerability to disease or injury. The distributions of social determinants are often shaped by public policies that reflect prevailing political ideologies of the area. The World Health Organization says that "the social determinants can be more important than health care or lifestyle choices in influencing health." and "This unequal distribution of health-damaging experiences is not in any sense a 'natural' phenomenon but is the result of a toxic combination of poor social policies, unfair economic arrangements here the already well-off and healthy become even ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
