Pacific Northwest Diabetes Research Institute
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Pacific Northwest Diabetes Research Institute
The Pacific Northwest Research Institute (PNRI) is a private non-profit biomedical and clinical research institute in the northwest United States, located in Seattle, Washington. Founded to investigate heart surgery, cancer, and endocrine diseases, its current focus is pioneering genetic research to find new solutions to improve human health. History The first such institute in the Pacific Northwest, it was created in 1956 by William B. Hutchinson as the Pacific Northwest Research Foundation (PNRF). A second-generation physician, founder Hutchinson (1909–1997) was a surgeon and an older brother of major league baseball pitcher and manager Fred Hutchinson, who died of lung cancer at age 45 in 1964. In 1972, PNRF received federal funding under the National Cancer Act of 1971 with the help of U.S. Senator Warren G. Magnuson to create in Seattle one of the 15 new cancer centers called for under 1971 Act; the Fred Hutchinson Cancer Research Center was founded in 1972 and its b ...
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Nonprofit Organization
A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in contrast with an entity that operates as a business aiming to generate a Profit (accounting), profit for its owners. A nonprofit is subject to the non-distribution constraint: any revenues that exceed expenses must be committed to the organization's purpose, not taken by private parties. An array of organizations are nonprofit, including some political organizations, schools, business associations, churches, social clubs, and consumer cooperatives. Nonprofit entities may seek approval from governments to be Tax exemption, tax-exempt, and some may also qualify to receive tax-deductible contributions, but an entity may incorporate as a nonprofit entity without securing tax-exempt status. Key aspects of nonprofits are accountability, trustworth ...
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Pitcher
In baseball, the pitcher is the player who throws ("pitches") the baseball from the pitcher's mound toward the catcher to begin each play, with the goal of retiring a batter, who attempts to either make contact with the pitched ball or draw a walk. In the numbering system used to record defensive plays, the pitcher is assigned the number 1. The pitcher is often considered the most important player on the defensive side of the game, and as such is situated at the right end of the defensive spectrum. There are many different types of pitchers, such as the starting pitcher, relief pitcher, middle reliever, lefty specialist, setup man, and the closer. Traditionally, the pitcher also bats. Starting in 1973 with the American League(and later the National League) and spreading to further leagues throughout the 1980s and 1990s, the hitting duties of the pitcher have generally been given over to the position of designated hitter, a cause of some controversy. The Japanese Central Le ...
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Research Institutes Established In 1956
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ...
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Non-profit Organizations Based In Seattle
A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in contrast with an entity that operates as a business aiming to generate a profit for its owners. A nonprofit is subject to the non-distribution constraint: any revenues that exceed expenses must be committed to the organization's purpose, not taken by private parties. An array of organizations are nonprofit, including some political organizations, schools, business associations, churches, social clubs, and consumer cooperatives. Nonprofit entities may seek approval from governments to be tax-exempt, and some may also qualify to receive tax-deductible contributions, but an entity may incorporate as a nonprofit entity without securing tax-exempt status. Key aspects of nonprofits are accountability, trustworthiness, honesty, and openness to eve ...
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Diabetes Organizations
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level (hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to loss of ...
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Medical Research Institutes In The United States
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an an ...
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Varietal
A varietal wine is a wine made primarily from a single named grape variety, and which typically displays the name of that variety on the wine label.The American Heritage Dictionary of the English Language, Fourth Edition, 2000.winepros.com.au. Examples of grape varieties commonly used in varietal wines are Cabernet Sauvignon, Chardonnay and Merlot. Wines that display the name of two or more varieties on their label, such as a Chardonnay-Viognier, are ''blends'' and not varietal wines. The term is frequently misused in place of vine variety; the term ''variety'' refers to the vine or grape, while ''varietal'' refers to the wine produced by a variety. The term was popularized in the US by Maynard Amerine at the University of California, Davis after Prohibition seeking to encourage growers to choose optimal vine varieties, and later promoted by Frank Schoonmaker in the 1950s and 1960s, ultimately becoming widespread during the California wine boom of the 1970s. Varietal wines are ...
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Puget Sound
Puget Sound ( ) is a sound of the Pacific Northwest, an inlet of the Pacific Ocean, and part of the Salish Sea. It is located along the northwestern coast of the U.S. state of Washington. It is a complex estuarine system of interconnected marine waterways and basins, with one major and two minor connections to the open Pacific Ocean via the Strait of Juan de Fuca—Admiralty Inlet being the major connection and Deception Pass and Swinomish Channel being the minor. Water flow through Deception Pass is approximately equal to 2% of the total tidal exchange between Puget Sound and the Strait of Juan de Fuca. Puget Sound extends approximately from Deception Pass in the north to Olympia in the south. Its average depth is and its maximum depth, off Jefferson Point between Indianola and Kingston, is . The depth of the main basin, between the southern tip of Whidbey Island and Tacoma, is approximately . In 2009, the term Salish Sea was established by the United States Board o ...
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Fred Hutchinson Cancer Research Center
The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington. History The center grew out of the Pacific Northwest Research Foundation, founded in 1956 by William B. Hutchinson (1909–1997). The Foundation was dedicated to the study of heart surgery, cancer, and diseases of the endocrine system. Hutchinson's younger brother Fred (1919–1964) was a major league pitcher and manager who died of lung cancer at age 45. The next year, William Hutchinson established the Fred Hutchinson Cancer Research Center as a division of the Pacific Northwest Research Foundation.Louis Fiset, December 30, 2004 for HistoryLink: The Free, Online Encyclopedia of Washington State HistorHutchinson, Dr. William B. (1909-1997)/ref> In 1972, with the help of Senator Warren G. Magnuson, PNRF received federal funding under the National Cancer Act of 19 ...
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Warren G
Warren Griffin III (born November 10, 1970) is an American rapper and producer known for his role in West Coast rap's 1990s ascent.Steve Huey"Warren G: Biography" ''AllMusic.com'', Netaktion LLC, visited May 8, 2020. Along with Snoop Dogg and Nate Dogg, he formed the hip-hop trio 213, named for Long Beach's area code. A pioneer of G-funk, he attained mainstream success with the 1994 single " Regulate", a duet with Nate Dogg. The younger stepbrother of rapper Dr. Dre, he introduced him to Snoop Dogg, who Dre later signed. His debut album, '' Regulate... G Funk Era'', debuted at #2 on the US Billboard 200 chart, selling 176,000 in its opening week. The album later went on the sell over 3 million copies in the US and was certified 3x multi-platinum. The single " Regulate" spent 18 weeks in the Top 40 of the Billboard Hot 100, with three weeks at No. 2, while " This D.J.", reached No. 9. Both songs earned Grammy nominations. Three songs from his second album, ''Take a Look Over Y ...
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United States Senate
The United States Senate is the upper chamber of the United States Congress, with the House of Representatives being the lower chamber. Together they compose the national bicameral legislature of the United States. The composition and powers of the Senate are established by Article One of the United States Constitution. The Senate is composed of senators, each of whom represents a single state in its entirety. Each of the 50 states is equally represented by two senators who serve staggered terms of six years, for a total of 100 senators. The vice president of the United States serves as presiding officer and president of the Senate by virtue of that office, despite not being a senator, and has a vote only if the Senate is equally divided. In the vice president's absence, the president pro tempore, who is traditionally the senior member of the party holding a majority of seats, presides over the Senate. As the upper chamber of Congress, the Senate has several powers o ...
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National Cancer Act Of 1971
The "war on cancer" is the effort to find a cure for cancer by increased research to improve the understanding of cancer biology and the development of more effective cancer treatments, such as targeted drug therapies. The aim of such efforts is to eradicate cancer as a major cause of death. The signing of the National Cancer Act of 1971 by United States president Richard Nixon is generally viewed as the beginning of this effort, though it was not described as a "war" in the legislation itself. Despite significant progress in the treatment of certain forms of cancer (such as childhood leukemia), cancer in general remains a major cause of death half a century after this war on cancer began, leading to a perceived lack of progress and to new legislation aimed at augmenting the original National Cancer Act of 1971. New research directions, in part based on the results of the Human Genome Project, hold promise for a better understanding of the genetic factors underlying cancer, and th ...
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