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PSG2
Function Human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large quantities by the placental trophoblast and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has shown that PSG forms a subset of the carcinoembryonic antigen (CEA) gene family that belongs to the immunoglobulin superfamily genes. Members of the CEA family consist of a single N domain that is structurally similar to the immunoglobulin variable domain, followed by a variable number of constant immunoglobulin-like A and / or B domains. Most PSGs have the Argglyasp (RGD) motif in the N-terminal domain. It has been shown to act as an adhesion recognition signal for some integrins. Pregnancy-specific beta-1-glycoprotein 2 is a protein that in humans is encoded by the ''PSG2'' gene. References Further reading * * * * * * {{protein-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
