PGL Major Kraków
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PGL Major Kraków
PGL may refer to: * Paraganglioma, a type of rare neuroendocrine neoplasm * The succinate dehydrogenase SDHD (previously known as PGL1) and SDHC (previously PGL3) * Persistent generalized lymphadenopathy * PGL (company), UK * Polish Aviation Group ( Polish: ''Polska Grupa Lotnicza'') * Professional Gamers League, former US electronic sports league * Projective linear group, in mathematics {{disambig ...
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Paraganglioma
A paraganglioma is a rare neuroendocrine neoplasm that may develop at various body sites (including the head, neck, thorax and abdomen). When the same type of tumor is found in the adrenal gland, they are referred to as a pheochromocytoma. They are rare tumors, with an overall estimated incidence of 1/300,000. There is no test that determines benign from malignant tumors; long-term follow-up is therefore recommended for all individuals with paraganglioma. Signs and symptoms Most paragangliomas are asymptomatic, present as a painless mass, or create symptoms such as hypertension, tachycardia, headache, and palpitations. While all contain neurosecretory granules, only in 1–3% of cases is secretion of hormones such as catecholamines abundant enough to be clinically significant; in that case manifestations often resemble those of pheochromocytomas (intra-medullary paraganglioma). Genetics About 75% of paragangliomas are sporadic; the remaining 25% are hereditary (and have an increas ...
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SDHD
Succinate dehydrogenase biquinonecytochrome b small subunit, mitochondrial (CybS), also known as succinate dehydrogenase complex subunit D (SDHD), is a protein that in humans is encoded by the ''SDHD'' gene. Names previously used for SDHD were PGL and PGL1. Succinate dehydrogenase is an important enzyme in both the citric acid cycle and the electron transport chain. Structure The SDHD gene is located on chromosome 11 at locus 11q23 and it spans 8,978 base pairs. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. The SDHD gene produces a 17 kDa protein composed of 159 amino acids. The SDHD protein is one of the two integral transmembrane subunits anchoring the four-subunit succinate dehydrogenase (Complex II) protein complex to the matrix side of the mitochondrial inner membrane. The other transmembrane subunit is SDHC. The SDHC/SDHD dimer is connected to the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit. Functi ...
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SDHC (gene)
Succinate dehydrogenase complex subunit C, also known as succinate dehydrogenase cytochrome b560 subunit, mitochondrial, is a protein that in humans is encoded by the ''SDHC'' gene. This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with pheochromocytomas and paragangliomas. Alternatively spliced transcript variants have been described. Structure The gene that codes for the SDHC protein is nuclear, even though the protein is located in the inner membrane of the mitochondria. The location of the gene in humans ...
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Persistent Generalized Lymphadenopathy
Persistent generalized lymphadenopathy (PGL) is enlarged, painless, non-tender lymph nodes occurring in a couple of different areas for more than three to six months for which no other reason can be found. To expand, the common site where PGL occurs is within the head and neck region; parotid gland alterations and nasopharyngeal lymphatic tissue enlargement are often frequent comorbidities of Persistent generalized lymphadenopathy. Due to lymphoproliferation in the intraglandular lymphoid tissue, obstruction within the epithelium results in cystic expansion, which is the cause of cystic parotid lesions found in PGL.HIV lymphadenopathy: Differential diagnosis and important imaging features : American Journal of roentgenology : Vol. 216, no. 2 (AJR). American Journal of Roentgenology. (n.d.). Retrieved November 18, 2022, from https://www.ajronline.org/doi/full/10.2214/AJR.19.22334?mobileUi=0 This condition frequently occurs in people in the latency period of HIV/AIDS. The lymphatic s ...
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PGL (company)
PGL Travel Ltd is a company founded in 1957 and is a provider of school activity courses and summer camps for children in the United Kingdom. Along with NST, European Study Tours and StudyLink it is a part of the HB Education group, owned by Midlothian Capital Partners. History PGL Travel Ltd. was established in 1957 as ‘PGL Voyages’ and is a provider of school activity courses and adventure holidays for children. In the 1960s and early 1970s the ‘PGL Experience' was aimed at young adults and based on three main activities - canoeing, sailing and pony trekking, with accommodation in tents. PGL moved into the school and group travel market and during the 1980s expanded, purchasing more properties, ranging from a mansion house in Perthshire to a converted farm in Oxfordshire. PGL opened a headquarters in the South of France and became one of the first UK organisers of canoeing holidays in the Ardèche Gorge. In the early 90s the acquisition by the company of the form ...
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Polish Aviation Group
Polish Aviation Group is Poland's largest aviation company. It was founded in 2018 with an aim to merge Polish companies including LOT Polish Airlines, LOT Aircraft Maintenance Services, LS Airport Services and LS Technics. The group's headquarters are in Warsaw. History PGL (Polska Grupa Lotnicza) was formed in January 2018 and consists of LOT Polish Airlines, LOT Aircraft Maintenance Services and LS Airport Services and LS Technics which were merged into the group in early October 2018. Its CEO is Rafał Milczarski. It was started with a capital of PLN 1.2 billion (EUR 290 million) as a joint stock company in January 2018. The new state-owned Polish Aviation Group (PGL), endowed with capital of PLN 2.5 billion, brings together the country’s largest aviation service providers. On 24 January 2020 PGL announced that it would acquire Condor Flugdienst, and that the transaction was expected to be completed in April 2020 after consideration from anti-trust regulators. On 2 Apri ...
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Polish Language
Polish (Polish: ''język polski'', , ''polszczyzna'' or simply ''polski'', ) is a West Slavic language of the Lechitic group written in the Latin script. It is spoken primarily in Poland and serves as the native language of the Poles. In addition to being the official language of Poland, it is also used by the Polish diaspora. There are over 50 million Polish speakers around the world. It ranks as the sixth most-spoken among languages of the European Union. Polish is subdivided into regional dialects and maintains strict T–V distinction pronouns, honorifics, and various forms of formalities when addressing individuals. The traditional 32-letter Polish alphabet has nine additions (''ą'', ''ć'', ''ę'', ''ł'', ''ń'', ''ó'', ''ś'', ''ź'', ''ż'') to the letters of the basic 26-letter Latin alphabet, while removing three (x, q, v). Those three letters are at times included in an extended 35-letter alphabet, although they are not used in native words. The traditional ...
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Professional Gamers League
The AMD Professional Gamers League (PGL), founded around 1997, was one of the first professional computer gaming eSports leagues. The PGL was run by Total Entertainment Network and was sponsored by AMD. The first professional tournament they held was for ''StarCraft'' in September 1997. The league was official unveiled at a press conference at Candlestick Park in San Francisco on November 3, 1997. It was sponsored by Microsoft, Nvidia, and Levi Strauss & Co. The organization raised over $1.2mil USD in sponsorship money. Nearly 1,400 players took part in the first ''Quake'' tournament, which took place online. The first-ever Professional Gamers League Finals took place on January 30 and January 31, 1998, in Seattle, Washington at the Sega GameWorks super-arcade. Two games were played in this competition, '' Command & Conquer: Red Alert'' and '' Quake''. Both tournaments featured 1 on 1 play with David "DeepBlue" Magro winning the ''Red Alert'' tournament and Dennis "Thresh" Fon ...
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