Proton-Translocating NAD(P) Transhydrogenase
Proton-Translocating NAD(P)+ Transhydrogenase (E.C is an enzyme in that catalyzes the translocation of hydrons that are connected to the redox reaction NADH + NADP+ + H+outside => NAD+ + NADPH + H+inside EC Number 7.1.1.1 EC 7 – Translocases are a grouping of enzymes with a common function of assisting to move a molecule, typically across a membrane. EC 7.1 – enzymes that catalyze translocation of hydrons (the positive cations of all hydrogen isotopes e.g. protons, deuterons, tritons) EC 7.1.1 – enzymes that catalyze translocation of hydrons that have a tie to oxidoreductase reactions EC 7.1.1.1 – proton-translocating NAD(P)+ transhydrogenase. Reaction pathway The reaction that this enzyme catalyzes is NADH + NADP+ + H+outside => NAD+ + NADPH + H+inside This redox reaction is a transfer of hydride equivalents from NADH to NADP+ coupled to a translocation of protons across a membrane. NADP+ is reduced to NADPH by NADH, which is oxidized into NAD+. This reduction is ...
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