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Predicted Environmental Concentration
Calculated value of a chemical in the environment on the basis of exposure models such as the European Union System for the Evaluation of Substances (EUSES). Used in the context of Chemical Safety Assessments (CSA) and referenced in Chemical Safety Reports (CSR). PECs may be compared with Measured Environmental Concentration An Measured Environmental Concentration (MEC) relates to a chemical substance found in an environmental sample. The concentration of the compound may result from direct contamination, transformation and/or metabolization of a different chemical cont ...s (MEC) if available. Toxicology Chemical safety {{med-toxic-stub ...
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European Union System For The Evaluation Of Substances
The European Union System for the Evaluation of Substances (EUSES) is a mathematical model for calculation of Predicted Environmental Concentrations (PEC) and human exposure. It may be used in Chemical Safety Assessments (CSA) and be cited in Chemical Safety Reports (CSR). EUSES is provided free of charge from the European Chemical Bureau website and has the form of a Microsoft Excel Microsoft Excel is a spreadsheet developed by Microsoft for Windows, macOS, Android and iOS. It features calculation or computation capabilities, graphing tools, pivot tables, and a macro programming language called Visual Basic for App ... sheet. External linksEx-ECBEUSES 2.1.1 User Manual
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Measured Environmental Concentration
An Measured Environmental Concentration (MEC) relates to a chemical substance found in an environmental sample. The concentration of the compound may result from direct contamination, transformation and/or metabolization of a different chemical contaminant, natural origin or a combination of these sources. MEC is to be used as a reference in the context of Chemical Safety Assessments (CSA) and should be compared with the respective Predicted Environmental Concentration (PEC) and Predicted No-Effect Concentration The predicted no-effect concentration (PNEC) is the concentration of a chemical which marks the limit at which below no adverse effects of exposure in an ecosystem are measured. PNEC values are intended to be conservative and predict the concentrati ... (PNEC) in order to decide whether exposure model is valid and the compound related risk is controlled. References Chemical safety Concentration indicators Toxicology {{med-toxic-stub ...
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Toxicology
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested in the treatment of leukemia. The word ''toxicology'' () is a neocla ...
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