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Podospora Appendiculata
''Podospora appendiculata'' is a coprophilous fungus that is most commonly found in the dung of lagomorphs, such as hares and rabbits, in temperate to warm climates. A member of the division Ascomycota, ''P. appendiculata'' is characterized by ovoid, hair-studded perithecia which can bear a distinctive violaceous colouring and peridia which are coriaceous, or leathery, in texture. ''Podospora appendiculata'' has been shown to produce three compounds (Appenolide A, Appenolide B, and Appenolide C) with antimicrobial properties. History and taxonomy The fungus was first collected by the German mycologist Bernhard Auerswald from hare dung found near the German city of Leipzig. Auerswald sent a sample in a letter to Gustav Niessl von Mayendorf, who published a description of the species under the name ''Sordaria appendiculata'' in 1872 before reclassifying it under the genus ''Podospora'' in 1883. Contesting Auerswald and Niessl's work, Heinrich Georg Winter later argued in 188 ...
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Bernhard Auerswald
Bernhard Auerswald (1818–1870) was a German mycologist and professor from Leipzig. He participated as chief correspondent of botany, sending specimens that his colleague Heinrich Moritz Willkomm Heinrich Moritz Willkomm (29 June 1821, Herwigsdorf – 26 August 1895, Schloss Wartenberg in Wartenberg am Rollberg, Bohemia) was a German academic and botanist. He studied medicine at the University of Leipzig, later being named a prof ... collected and sent to him from his expeditions. Published works * ''Botanische Unterhaltungen zum Verständniss der heimathlichen Flora''. Leipzig: H. Mendelssohn, 1858 * ''Anleitung zum rationellen Botanisiren''. Leipzig: Veit & Comp., 1860 * ''Unsere Heimats-Kräuter als Hausmittel : eine ausführliche Beschreibung aller heilwirkenden Pflanzen und Kräuter deren Fundort, praktische Verwendung und Verwertung in den verschiedensten Krankheitsfällen des menschlichen Lebens. Nach den neuesten und besten Quellen bearbeitet''. Dresden 1860 ...
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Petter Adolf Karsten
Petter Adolf Karsten (16 February 1834 – 22 March 1917) was a Finnish mycologist, the foremost expert on the fungi of Finland in his day, and known in consequence as the "father of Finnish mycology". Karsten was born in Merimasku near Turku, studied at the University of Helsinki, and then moved to the inland of Tammela, where he spent most of his life with teaching botany and doing research at the Mustiala Agriculture Institute (now the Faculty of Agriculture of the HAMK University of Applied Sciences). He amassed a vast collection, both by his own efforts and those of his correspondents, and named about 200 new genera and 2,000 new species. In his mycological studies he extensively used the microscope and can be considered as the pioneer of fungal microscopy. ''Karstenia'', the international journal of mycology published by the Finnish Mycological Society, is dedicated to Karsten. Honours In 1885, botanist Elias Magnus Fries published ''Karstenia'' is a genus of fungi in the ...
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Autoinducer 2
Autoinducer-2 (AI-2), a furanosyl borate diester or tetrahydroxy furan (species dependent), is a member of a family of signaling molecules used in quorum sensing. AI-2 is one of only a few known biomolecules incorporating boron. First identified in the marine bacterium ''Vibrio harveyi'', AI-2 is produced and recognized by many Gram-negative and Gram-positive bacteria. AI-2 arises by the reaction of 4,5-Dihydroxy-2,3-pentanedione, which is produced enzymatically with boric acid, and is recognized by the two-component sensor kinase LuxPQ in Vibrionaceae. AI-2 is actively transported by the Lsr ABC-type transporter into the cell in Enterobacteriaceae and few other bacterial taxa ('' Pasteurella'', ''Photorhabdus'', ''Haemophilus ''Haemophilus'' is a genus of Gram-negative, pleomorphic, coccobacilli bacteria belonging to the family Pasteurellaceae. While ''Haemophilus'' bacteria are typically small coccobacilli, they are categorized as pleomorphic bacteria because of ...' ...
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Bacillus Subtilis
''Bacillus subtilis'', known also as the hay bacillus or grass bacillus, is a Gram-positive, catalase-positive bacterium, found in soil and the gastrointestinal tract of ruminants, humans and marine sponges. As a member of the genus ''Bacillus'', ''B. subtilis'' is rod-shaped, and can form a tough, protective endospore, allowing it to tolerate extreme environmental conditions. ''B. subtilis'' has historically been classified as an obligate aerobe, though evidence exists that it is a facultative anaerobe. ''B. subtilis'' is considered the best studied Gram-positive bacterium and a model organism to study bacterial chromosome replication and cell differentiation. It is one of the bacterial champions in secreted enzyme production and used on an industrial scale by biotechnology companies. Description ''Bacillus subtilis'' is a Gram-positive bacterium, rod-shaped and catalase-positive. It was originally named ''Vibrio subtilis'' by Christian Gottfried Ehrenberg, and renamed ''B ...
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Disk Diffusion Test
The disk diffusion test (also known as the agar diffusion test, Kirby–Bauer test, disc-diffusion antibiotic susceptibility test, disc-diffusion antibiotic sensitivity test and KB test) is a culture-based microbiology assay used in diagnostic and drug discovery laboratories. In diagnostic labs, the assay is used to determine the susceptibility of bacteria isolated from a patient's infection to clinically approved antibiotics. This allows physicians to prescribe the most appropriate antibiotic treatment. In drug discovery labs, especially bioprospecting labs, the assay is used to screen biological material (e.g. plant extracts, bacterial fermentation broths) and drug candidates for antibacterial activity. When bioprospecting, the assay can be performed with paired strains of bacteria to achieve dereplication and provisionally identify antibacterial mechanism of action. In diagnostic laboratories, the test is performed by inoculating the surface of an agar plate with bacte ...
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Candida Albicans
''Candida albicans'' is an opportunistic pathogenic yeast that is a common member of the human gut flora. It can also survive outside the human body. It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults. It is usually a commensal organism, but it can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the genus '' Candida'' that causes the human infection candidiasis, which results from an overgrowth of the fungus. Candidiasis is, for example, often observed in HIV-infected patients. ''C. albicans'' is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. ''C. albicans'', ''C. tropicalis'', ''C. parapsilosis'', and ''C. glabrata'' are together responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to ''C. albicans''. ...
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Competition (biology)
Competition is an interaction between organisms or species in which both require a resource that is in limited supply (such as food, water, or territory). Competition lowers the fitness of both organisms involved since the presence of one of the organisms always reduces the amount of the resource available to the other. In the study of community ecology, competition within and between members of a species is an important biological interaction. Competition is one of many interacting biotic and abiotic factors that affect community structure, species diversity, and population dynamics (shifts in a population over time). There are three major mechanisms of competition: interference, exploitation, and apparent competition (in order from most direct to least direct). Interference and exploitation competition can be classed as "real" forms of competition, while apparent competition is not, as organisms do not share a resource, but instead share a predator. Competition among membe ...
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In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ...
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Teleomorph, Anamorph And Holomorph
In mycology, the terms teleomorph, anamorph, and holomorph apply to portions of the life cycles of fungi in the phyla Ascomycota and Basidiomycota: *Teleomorph: the sexual reproductive stage (morph), typically a fruiting body. *Anamorph: an asexual reproductive stage (morph), often mold-like. When a single fungus produces multiple morphologically distinct anamorphs, these are called synanamorphs. *Holomorph: the whole fungus, including anamorphs and teleomorph. Dual naming of fungi Fungi are classified primarily based on the structures associated with sexual reproduction, which tend to be evolutionarily conserved. However, many fungi reproduce only asexually, and cannot easily be classified based on sexual characteristics; some produce both asexual and sexual states. These problematic species are often members of the Ascomycota, but a few of them belong to the Basidiomycota. Even among fungi that reproduce both sexually and asexually, often only one method of reproduction can be ...
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Hyphae
A hypha (; ) is a long, branching, filamentous structure of a fungus, oomycete, or actinobacterium. In most fungi, hyphae are the main mode of vegetative growth, and are collectively called a mycelium. Structure A hypha consists of one or more cells surrounded by a tubular cell wall. In most fungi, hyphae are divided into cells by internal cross-walls called "septa" (singular septum). Septa are usually perforated by pores large enough for ribosomes, mitochondria, and sometimes nuclei to flow between cells. The major structural polymer in fungal cell walls is typically chitin, in contrast to plants and oomycetes that have cellulosic cell walls. Some fungi have aseptate hyphae, meaning their hyphae are not partitioned by septa. Hyphae have an average diameter of 4–6 µm. Growth Hyphae grow at their tips. During tip growth, cell walls are extended by the external assembly and polymerization of cell wall components, and the internal production of new cell membrane. ...
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Germ Pore
A germ pore is a small pore in the outer wall of a fungal spore through which the germ tube exits upon germination. It can be apical or eccentric in its location, and, on light microscopy, may be visualized as a lighter coloured area on the cell wall. Apical germ pore is mushroom spore which has a pore at one end. Some spores have a hole in the cell wall where the first strand of germinating mycelium emerges. If the cell wall is divided from one end to the other, this is called a germ slit. Commonly the germ pore is at one end of the mushroom spore and is called an apical pore. Mushroom genera with apical germ pores include ''Agrocybe'', ''Panaeolus'', ''Psilocybe'', and ''Pholiota''. See also *mycelium *spore In biology, a spore is a unit of sexual or asexual reproduction that may be adapted for dispersal and for survival, often for extended periods of time, in unfavourable conditions. Spores form part of the life cycles of many plants, algae, f ... External linksIMA ...
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