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Patrick Couvreur
Patrick Couvreur, born 1950 in Schaerbeek (Brussels), is a French pharmacologist who specialises in medical nanotechnology and is currently professor at the University of Paris-Sud. Couvreur was elected as a member into the National Academy of Engineering in 2015 for advances in nanomedicine and commercialization of targeted nanotechnology systems for cancer treatment. Biography Patrick Couvreur obtained his Candidature in pharmaceutical science in 1969, at the University of Namur,Patrick Couvreur, pionnier en nanomédecine (UNamur followed by a diploma in pharmacy in 1972, at the Catholic University of Louvain (UCL). He received a Doctorate in pharmaceutical science in 1975 from the same university, where he worked in the laboratory next door to the Belgian Nobel Prize winner, Christian de Duve, who was an inspiration for his subsequent career. From 1976 to 1977 he was a postdoctoral researcher at ETH Zurich, before joining the Catholic University of Louvain, first as a sen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Schaerbeek
(French language, French and History of Dutch orthography, archaic Dutch, ) or (contemporary Dutch language, Dutch, ) is one of the List of municipalities of the Brussels-Capital Region, 19 municipalities of the Brussels, Brussels-Capital Region, Belgium. Located in the north-eastern part of the region, it is bordered by the City of Brussels, Etterbeek, Evere and Saint-Josse-ten-Noode. In common with all of Brussels' municipalities, it is legally Multilingualism, bilingual (French–Dutch). Schaerbeek has a multicultural identity stemming from its diverse population. , the municipality had a total population of 132,861 inhabitants, 66,010 men and 66,851 women, for an area of , which gives a population density of . Toponymy Etymology The first mention of Schaerbeek's name was ''Scarenbecca'', recorded in a document from the Roman Catholic Archdiocese of Cambrai, Bishop of Cambrai in 1120. The origin of the name may come from the Franconian languages, Franconian (Old Dutch) w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christian De Duve
Christian René Marie Joseph, Viscount de Duve (2 October 1917 – 4 May 2013) was a Nobel Prize-winning Belgian cytologist and biochemist. He made serendipitous discoveries of two cell organelles, peroxisome and lysosome, for which he shared the Nobel Prize in Physiology or Medicine in 1974 with Albert Claude and George E. Palade ("for their discoveries concerning the structural and functional organization of the cell"). In addition to peroxisome and lysosome, he invented scientific names such as autophagy, endocytosis, and exocytosis in a single occasion. The son of Belgian refugees during the First World War, de Duve was born in Thames Ditton, Surrey, England. His family returned to Belgium in 1920. He was educated by the Jesuits at Our Lady College, Antwerp, and studied medicine at the Catholic University of Leuven. Upon earning his MD in 1941, he joined research in chemistry, working on insulin and its role in diabetes mellitus. His thesis earned him the highest universi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
José-Alain Sahel
José-Alain Sahel is a French ophthalmologist and scientist. He is currently the chair of the Department of Ophthalmology at the University of Pittsburgh School of Medicine, director of the UPMC Eye Center, and the Eye and Ear Foundation Chair of Ophthalmology. Dr. Sahel previously led the Vision Institute (French: Institut de la Vision) in Paris, a research center associated with the one of the oldest eye hospitals of Europe - Quinze-Vingts National Eye Hospital in Paris, founded in 1260. He is a pioneer in the field of artificial retina and eye regenerative therapies. He is a member of the French Academy of Sciences. Biography José-Alain Sahel was born in Tlemcen (Algeria) in 1955. He has studied medicine in the Strasbourg University and in Lariboisière, St. Louis. In 1980 he received a Doctorate of Medicine with a Medal of the Faculty of Paris and in 1984 obtained his Specialisation in Ophthalmology. He spent his first 20 professional years in the University Hospital of Str ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alain Benoit
Alain Benoit (born 1948) is a French physicist specialising in low temperature physics. He was awarded the CNRS silver medal in 1993 and the CNRS innovation medal in 2012. He is a research director at the Grenoble Very Low Temperature Centre, where he contributed to the cooling of the European Space Agency's Planck telescope to 0.1 K. He was elected a member of the French Academy of Sciences The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV of France, Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific me ... in 2002. References 1948 births Living people French National Centre for Scientific Research awards Cryogenics French physicists Research directors of the French National Centre for Scientific Research {{France-physicist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Research Council
The European Research Council (ERC) is a public body for funding of scientific and technological research conducted within the European Union (EU). Established by the European Commission in 2007, the ERC is composed of an independent Scientific Council, its governing body consisting of distinguished researchers, and an Executive Agency, in charge of the implementation. It forms part of the framework programme of the union dedicated to research and innovation, Horizon 2020, preceded by the Seventh Research Framework Programme (FP7). The ERC budget is over €13 billion from 2014 – 2020 and comes from the Horizon 2020 programme, a part of the European Union's budget. Under Horizon 2020 it is estimated that around 7,000 ERC grantees will be funded and 42,000 team members supported, including 11,000 doctoral students and almost 16,000 post-doctoral researchers. Researchers from any field can compete for the grants that support pioneering projects. The ERC competitions are open ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Active Ingredient
An active ingredient is any ingredient that provides biologically active or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the body of humans or animals. The similar terms active pharmaceutical ingredient (also abbreviated as API) and bulk active are also used in medicine, and the term active substance may be used for natural products. Some medication products may contain more than one active ingredient. The traditional word for the active pharmaceutical agent is pharmacon or pharmakon (from el, φάρμακον, adapted from '' pharmacos'') which originally denoted a magical substance or drug. The terms active constituent or active principle are often chosen when referring to the active substance of interest in a plant (such as salicylic acid in willow bark or arecoline in areca nuts), because the word "ingredient" in many minds connotes a sense of human agency (that is, something t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Patent Office
The European Patent Office (EPO) is one of the two organs of the European Patent Organisation (EPOrg), the other being the Administrative Council. The EPO acts as executive body for the organisationGower's Report on Intellectual Property , para 1.34 while the Administrative Council acts as its supervisory body as well as, to a limited extent, its legislative body. The actual legislative power to revise the lies with the Contracting States themselves when meeting at a Conference of the Contracting States. Within the European Patent Office, [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Squalene
Squalene is an organic compound. It is a triterpenoid with the formula C30H50. It is a colourless oil, although impure samples appear yellow. It was originally obtained from shark liver oil (hence its name, as ''Squalus'' is a genus of sharks). All plants and animals produce squalene as a biochemical intermediate to sterol biosynthesis. An estimated 12% of bodily squalene in humans is found in Sebaceous gland, sebum. Squalene has a role in topical skin lubrication and protection. Squalene is a precursor (chemistry), precursor for synthesis of all plant and animal sterols, including cholesterol and steroid hormones in the human body. Squalene is an important ingredient in some vaccine adjuvants: The Novartis and GlaxoSmithKline adjuvants are called MF59 and AS03, respectively. Role in steroid synthesis Squalene is the biochemical precursor to steroids. The squalene conversion begins with oxidation (via squalene monooxygenase) of one of its terminal double bonds, resulting in 2,3- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanomedicine
Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and BioBrick, biological devices, to Nanoelectronics, nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as Molecular machine#Biological, biological machines. Current problems for nanomedicine involve understanding the issues related to Nanotoxicology, toxicity and Implications of nanotechnology, environmental impact of Nanomaterials, nanoscale materials (materials whose structure is on the scale of nanometers, i.e. billionths of a meter). Functionalities can be added to nanomaterials by interfacing them with biological molecules or structures. The size of nanomaterials is similar to that of most biological molecules and structures; therefore, nanomaterials can be useful for both in vivo and in vitro biomedical research and applications. Thus far, the integration of nanomaterials with biology has led to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Vectorization
In pharmacology and medicine vectorization of drugs refers to (intracellular) targeting with plastic, noble metal or silicon nanoparticles or liposomes to which pharmacologically active substances are reversibly bound or attached by adsorption. CNRS researchers have devised a way to overcome the problem of multidrug resistance using polyalkyl cyanoacrylate (PACA) nanoparticles as "vectors". As a developing concept, drug nanocarriers are expected to play a major role in delivering multiple drugs to tumor tissues by overcoming biological barriers. References See also *Vector (molecular biology) *Cancer treatment *Nanomedicine *Nanobiotechnology Nanobiotechnology, bionanotechnology, and nanobiology are terms that refer to the intersection of nanotechnology and biology. Given that the subject is one that has only emerged very recently, bionanotechnology and nanobiotechnology serve as blan ... * Paul Ehrlich#Magic bullet * Gold nanobeacons Pharmacology Nanomedicine {{p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collège De France
The Collège de France (), formerly known as the ''Collège Royal'' or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment (''grand établissement'') in France. It is located in Paris near La Sorbonne. The Collège de France is considered to be France's most prestigious research establishment. Research and teaching are closely linked at the Collège de France, whose ambition is to teach "the knowledge that is being built up in all fields of literature, science and the arts". It offers high-level courses that are free, non-degree-granting and open to all without condition or registration. This gives it a special place in the French intellectual landscape. Overview The Collège is considered to be France's most prestigious research establishment. As of 2021, 21 Nobel Prize winners and 9 Fields Medalists have been affiliated with the Collège. It does not grant degrees. Each professor is required to give lectures where ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
