Paget's Disease (other)

	Paget's Disease (other) Paget's disease may refer to several conditions described by Sir James Paget, surgeon and pathologist: * Paget's disease of bone (most common use of the term "Paget's disease") * Paget's disease of the breast * Paget–Schroetter disease * Paget's abscess * Extramammary Paget's disease Extramammary Paget's Disease (EMPD) is a rare and slow-growing malignancy which occurs within the epithelium and accounts for 6.5% of all Paget's disease. The clinical presentation of this disease is similar to the characteristics of mammary Pa ... (EMPD) {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	James Paget Sir James Paget, 1st Baronet FRS HFRSE (11 January 1814 – 30 December 1899) (, rhymes with "gadget") was an English surgeon and pathologist who is best remembered for naming Paget's disease and who is considered, together with Rudolf Virchow, as one of the founders of scientific medical pathology. His famous works included ''Lectures on Tumours'' (1851) and ''Lectures on Surgical Pathology'' (1853). There are several medical conditions which were described by, and later named after, Paget: * Paget's disease of bone * Paget's disease of the nipple (a form of intraductal breast cancer spreading into the skin around the nipple) ** Extramammary Paget's disease refers to a group of similar, more rare skin lesions discovered by Radcliffe Crocker in 1889 which affect the male and female genitalia. * Paget–Schroetter disease * Paget's abscess, an abscess that recurs at the site of a former abscess which had resolved. Life Paget was born in Great Yarmouth, England, on 11 January ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Paget's Disease Of Bone Paget's disease of bone (commonly known as Paget's disease or, historically, osteitis deformans) is a condition involving cellular remodeling and deformity of one or more bones. The affected bones show signs of dysregulated bone remodeling at the microscopic level, specifically excessive bone breakdown and subsequent disorganized new bone formation. These structural changes cause the bone to weaken, which may result in deformity, pain, bone fractures, fracture or arthritis of associated joints. The exact cause is unknown, although leading theories indicate both genetic and acquired factors (see Paget's disease of bone#Causes, Causes). Paget's disease may affect any one or several bones of the body (most commonly pelvis, tibia, femur, lumbar vertebrae, and skull), but never the entire skeleton, and does not spread from bone to bone. Rarely, a bone affected by Paget's disease can transform into a Osteosarcoma, malignant bone cancer. As the disease often affects people differently, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Paget's Disease Of The Breast Paget's disease of the breast is a type of cancer that outwardly may have the appearance of eczema, with skin changes involving the nipple of the breast. The condition is an uncommon disease accounting for 1 to 4.3% of all breast cancers and was first described by Sir James Paget in 1874. The condition in itself often appears innocuous, limited to a surface appearance and it is sometimes dismissed, although actually indicative of underlying breast cancer. Immunohistochemistry of Paget cells and underlying breast cancer show a more aggressive, HER2-enriched, molecular subtype of breast cancer. Signs and symptoms Paget's disease of the breast can affect the nipple and areola. Symptoms typically only affect one breast. Symptoms may include: * ''Skin.'' The first symptom is usually an eczema-like rash. The skin of the nipple and areola may be red, itchy and inflamed. After a period of time, the skin may become flaky or scaly. * ''Discharge.'' A discharge, which may be straw-colored o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Paget–Schroetter Disease Paget–Schroetter disease (also known as venous thoracic outlet syndrome) is a form of upper extremity deep vein thrombosis (DVT), a medical condition in which blood clots form in the deep veins of the arms. These DVTs typically occur in the axillary and/or subclavian veins. Signs and symptoms The condition is relatively rare. It usually presents in young and otherwise healthy patients, and also occurs more often in males than females. The syndrome also became known as "effort-induced thrombosis" in the 1960s, as it has been reported to occur after vigorous activity, though it can also occur due to anatomic abnormality such as clavicle impingement or spontaneously. It may develop as a sequela of thoracic outlet syndrome. It is differentiated from secondary causes of upper extremity thrombosis caused by intravascular catheters. Paget–Schroetter syndrome was described once for a viola player who suddenly increased practice time 10-fold, creating enough repetitive pressure again ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Paget's Abscess A Paget's abscess, named by eminent British surgeon and pathologist Sir James Paget Sir James Paget, 1st Baronet FRS HFRSE (11 January 1814 – 30 December 1899) (, rhymes with "gadget") was an English surgeon and pathologist who is best remembered for naming Paget's disease and who is considered, together with Rudolf Virch ..., is an abscess that recurs at the site of a former abscess which had resolved. References External links WhoNamedIt.com {{disease-stub Bacterial diseases General surgery ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]