Orvar Swenson
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Orvar Swenson
Orvar Swenson (7 February 1909 – 13 April 2012) was a Swedish-born American pediatric surgeon. He discovered the cause of Hirschsprung's disease and in 1948, with Alexander Bill, performed the first pull-through operation in a child with megacolon, which then became a treatment for the disease. Initially a resident in pathology, he soon became an assistant professor of pediatric surgery at Harvard and later moved to Boston's Floating Hospital for Children as surgeon-in-chief, where he was the first pediatric surgeon on the staff at the hospital and where he began his research in Hirschsprung's disease. Subsequently he became surgeon-in-chief of Children's Memorial Hospital, where he remained until his retirement in 1973. In 1973, Swenson was elected president of the American Pediatric Surgical Association. He authored ''Swenson's Pediatric Surgery'', which ran into five editions and he was the recipient of a number of awards including the E. Mead Johnson Award, the William E. La ...
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Helsingborg
Helsingborg (, , , ) is a city and the seat of Helsingborg Municipality, Scania (Skåne), Sweden. It is the second-largest city in Scania (after Malmö) and ninth-largest in Sweden, with a population of 113,816 (2020). Helsingborg is the central urban area of northwestern Scania and Sweden's closest point to Denmark: the Danish city Helsingør is clearly visible about to the west on the other side of the Øresund. The HH Ferry route across the sound has more than 70 car ferry departures from each harbour every day. Historic Helsingborg, with its many old buildings, is a scenic coastal city. The buildings are a blend of old-style stone-built churches and a 600-year-old medieval fortress (Kärnan) in the city centre, and more modern commercial buildings. The streets vary from wide avenues to small alley-ways. ''Kullagatan'', the main pedestrian shopping street in the city, was the first pedestrian shopping street in Sweden. History Helsingborg is one of the oldest cities of wh ...
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Community Of Christ
The Community of Christ, known from 1872 to 2001 as the Reorganized Church of Jesus Christ of Latter Day Saints (RLDS), is an American-based international church, and is the second-largest denomination in the Latter Day Saint movement. The church reports Community of Christ membership statistics, 250,000 members in 1,100 congregations in 59 countries. The church traces its origins to Joseph Smith's establishment of Church of Christ (Latter Day Saints), the Church of Christ on April 6, 1830. His eldest son Joseph Smith III formally accepted leadership of the church on April 6, 1860 in the aftermath of the 1844 death of Joseph Smith. Although Community of Christ is a Restorationism (Christian primitivism), Restorationist faith expression, various practices and beliefs are congruent with Mainline (Protestant), mainline Protestant Christianity. While it generally rejects the term ''Mormon'' to describe its members, the church abides by a number of theological distinctions relatively ...
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Tracheoesophageal Fistula
A tracheoesophageal fistula (TEF, or TOF; see spelling differences) is an abnormal connection (fistula) between the esophagus and the trachea. TEF is a common congenital abnormality, but when occurring late in life is usually the sequela of surgical procedures such as a laryngectomy. Presentation Tracheoesophageal fistula is suggested in a newborn by copious salivation associated with choking, coughing, vomiting, and cyanosis coincident with the onset of feeding. Esophageal atresia and the subsequent inability to swallow typically cause polyhydramnios in utero. Rarely it may present in an adult. Complications Surgical repair can sometimes result in complications, including: * Stricture, due to gastric acid erosion of the shortened esophagus * Leak of contents at the point of anastomosis * Recurrence of fistula * Gastro-esophageal reflux disease * Dysphagia * Asthma-like symptoms, such as persistent coughing/wheezing * Recurrent chest infections * Tracheomalacia Associations ...
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Esophageal Atresia
Esophageal can refer to: * The esophagus * Esophageal arteries * Esophageal glands The esophageal glands are glands that are part of the digestive system of various animals, including humans. In humans Esophageal glands in humans are a part of a human digestive system. They are a small compound racemose exocrine glands of the m ... * Esophageal cancer {{disambig ...
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Esophagus
The esophagus (American English) or oesophagus (British English; both ), non-technically known also as the food pipe or gullet, is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach. The esophagus is a fibromuscular tube, about long in adults, that travels behind the trachea and heart, passes through the diaphragm, and empties into the uppermost region of the stomach. During swallowing, the epiglottis tilts backwards to prevent food from going down the larynx and lungs. The word ''oesophagus'' is from Ancient Greek οἰσοφάγος (oisophágos), from οἴσω (oísō), future form of φέρω (phérō, “I carry”) + ἔφαγον (éphagon, “I ate”). The wall of the esophagus from the lumen outwards consists of mucosa, submucosa (connective tissue), layers of muscle fibers between layers of fibrous tissue, and an outer layer of connective tissue. The mucosa is a stratified squamous epithel ...
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Biopsy
A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a disease. The tissue is then fixed, dehydrated, embedded, sectioned, stained and mounted before it is generally examined under a microscope by a pathologist; it may also be analyzed chemically. When an entire lump or suspicious area is removed, the procedure is called an excisional biopsy. An incisional biopsy or core biopsy samples a portion of the abnormal tissue without attempting to remove the entire lesion or tumor. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration biopsy. Biopsies are most commonly performed for insight into possible cancerous or inflammatory conditions. History T ...
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Pull-through Procedure
A pull-through procedure is the definitive operation for Hirschsprung disease, involving the removal of the abnormal segment of bowel that has no nerves, pulling through the normal bowel and connecting it to the anus. Several types of pull-through procedures exist including the Soave, Swenson and Duhamel. It can be performed using an open or minimally invasive approach. Aim A pull-through procedure is the definitive treatment for Hirschsprung's disease, with the aim of removing the abnormal part of the bowel and joining the normal part of the intestine with the anus. Swenson pull-through The original pull-through procedure was designed by Orvar Swenson and his colleague Alexander Bill. The abnormal aganglionic part of the bowel is resected down to the sigmoid colon and rectum, and the normal colon and the low rectum are subsequently joined. Duhamel pull-through The Duhamel pull-through is a modified Swenson's pull-through, first described in 1956. Soave pull-through The Soave ...
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Surgical Anastomosis
A surgical anastomosis is a surgical technique used to make a new connection between two body structures that carry fluid, such as blood vessels or bowel. For example, an arterial anastomosis is used in vascular bypass and a colonic anastomosis is used to restore colonic continuity after the resection of colon cancer. A surgical anastomosis can be created using suture sewn by hand, mechanical staplers and biological glues, depending on the circumstances. While an anastomosis may be end-to-end, equally it could be performed side-to-side or end-to-side depending on the circumstances of the required reconstruction or bypass. The term reanastomosis is also used to describe a surgical reconnection usually reversing a prior surgery to disconnect an anatomical anastomosis, e.g. tubal reversal after tubal ligation. __TOC__ Medical uses * Blood vessels: Arteries and veins. Most vascular procedures, including all vascular bypass operations (e.g. coronary artery bypass), aneurysmectomy ...
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Rectum
The rectum is the final straight portion of the large intestine in humans and some other mammals, and the Gastrointestinal tract, gut in others. The adult human rectum is about long, and begins at the rectosigmoid junction (the end of the sigmoid colon) at the level of the third sacral vertebra or the sacral promontory depending upon what definition is used. Its diameter is similar to that of the sigmoid colon at its commencement, but it is dilated near its termination, forming the rectal ampulla. It terminates at the level of the anorectal ring (the level of the puborectalis sling) or the dentate line, again depending upon which definition is used. In humans, the rectum is followed by the anal canal which is about long, before the gastrointestinal tract terminates at the anal verge. The word rectum comes from the Latin ''Wikt:rectum, rectum Wikt:intestinum, intestinum'', meaning ''straight intestine''. Structure The rectum is a part of the lower gastrointestinal tract ...
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Ganglion Cell
{{stack, A ganglion cell is a cell found in a ganglion. Examples of ganglion cells include: * Retinal ganglion cell (RGC) found in the ganglion cell layer of the retina * Cells that reside in the adrenal medulla, where they are involved in the sympathetic nervous system's release of epinephrine and norepinephrine into the blood stream * Cells of the sympathetic ganglia * Cells of the parasympathetic ganglia Parasympathetic ganglia are the autonomic ganglia of the parasympathetic nervous system. Most are small terminal ganglia or intramural ganglia, so named because they lie near or within (respectively) the organs they innervate. The exceptions are ... * Cells of the spiral ganglia Neurons ...
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Congenital Disease
A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can range from mild to severe. Birth defects are divided into two main types: structural disorders in which problems are seen with the shape of a body part and functional disorders in which problems exist with how a body part works. Functional disorders include metabolic and degenerative disorders. Some birth defects include both structural and functional disorders. Birth defects may result from genetic or chromosomal disorders, exposure to certain medications or chemicals, or certain infections during pregnancy. Risk factors include folate deficiency, drinking alcohol or smoking during pregnancy, poorly controlled diabetes, and a mother over the age of 35 years old. Many are believed to involve multiple factors. Birth defects may be visib ...
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University Of Miami
The University of Miami (UM, UMiami, Miami, U of M, and The U) is a private research university in Coral Gables, Florida. , the university enrolled 19,096 students in 12 colleges and schools across nearly 350 academic majors and programs, including the Leonard M. Miller School of Medicine in Miami's Health District, the law school on the main campus, and the Rosenstiel School of Marine and Atmospheric Science on Virginia Key with research facilities in southern Miami-Dade County. The University of Miami offers 138 undergraduate, 140 master's, and 67 doctoral degree programs. Since its founding in 1925, the university has attracted students from all 50 states and 173 foreign countries. With 16,954 faculty and staff as of 2021, the University of Miami is the second largest employer in Miami-Dade County. The university's main campus in Coral Gables spans , has over of buildings, and is located south of Downtown Miami, the heart of the nation's ninth largest and world's 65th ...
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