Oropouche Virus (Bunyaviridae Orthobunyavirus)
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Oropouche Virus (Bunyaviridae Orthobunyavirus)
''Oropouche orthobunyavirus'' (OROV) is one of the most common orthobunyaviruses. When OROV infects humans, it causes a rapid fever illness called Oropouche fever. OROV was originally reported in Trinidad and Tobago in 1955 from the blood sample of a fever patient and from a pool of ''Coquillettidia venezuelensis'' mosquitoes. In 1960, OROV was isolated from a sloth (''Pale-throated sloth, Bradypus tridactylus'') and a pool of ''Ochlerotatus serratus'' mosquitoes in Brazil. The virus is considered a public health threat in tropical and subtropical areas of Central and South America, with over half a million infected people as of 2005. OROV is considered to be an arbovirus due to the method of transmission by the mosquitoes ''Aedes serratus'' and ''Culex quinquefasciatus'' among sloths, marsupials, primates, and birds. Epidemic sites Between 1961 and 1980, OROV was reported in the northern state of Pará, Brazil, and from 1980 to 2004, OROV had spread to the Amazonas, Amapá, Acre, ...
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Orthobunyavirus
''Orthobunyavirus'' is a genus of the ''Peribunyaviridae'' family in the order ''Bunyavirales''. There are currently ~170 viruses recognised in this genus. These have been assembled into 103 species and 20 serogroups. The name ''Orthobunyavirus'' derives from Bunyamwera, Uganda, where the original type species ''Bunyamwera orthobunyavirus'' was first discovered, along with the prefix () meaning 'straight.' Epidemiology The genus is most diverse in Africa, Australia and Oceania, but occurs almost worldwide. Most orthobunyavirus species are transmitted by gnats and cause diseases of cattle. The ''California encephalitis virus'', the ''La Crosse virus'' and the ''Jamestown Canyon virus'' are North American species that cause encephalitis in humans. Virology *The virus is spherical, diameter 80 nm to 120 nm, and comprises three negative-sense single stranded RNA molecules encapsulated in a ribonucleocapsid. *The three RNAs are described as S, M and L (for Small, Medium ...
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