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Open Notebook Science
Open-notebook science is the practice of making the entire primary record of a research project publicly available online as it is recorded. This involves placing the personal, or laboratory, notebook of the researcher online along with all raw and processed data, and any associated material, as this material is generated. The approach may be summed up by the slogan 'no insider information'. It is the logical extreme of transparent approaches to research and explicitly includes the making available of failed, less significant, and otherwise unpublished experiments; so called 'dark data'.Freeing the Dark Data of Failed Scientific Experiments Goetz, T., Wired Magazine, Sept.25, 2007 The practice of open notebook science, although not the norm in the |
Research Project
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cameron Neylon
David Cameron Neylon is an advocate for open access and Professor of Research Communications at thCentre for Culture and Technologyat Curtin University. From 2012 - 2015 they were the Advocacy Director at the Public Library of Science. Education Neylon was educated at the University of Western Australia and the Australian National University where they were awarded a Doctor of Philosophy degree in Biophysics in 1999 for work on directed molecular evolution and DNA-binding specificity. Career In 2009 Neylon was a senior scientist at the ISIS neutron source of the Science and Technology Facilities Council. From 2012 to 2015 they served as director of advocacy at the Public Library of Science. They joined The Centre for Culture and Technology (CCAT) at Curtin University in 2015 as Professor of Research Communications. Neylon is an original drafter of the Panton Principles and opposed the Research Works Act and advocates for governmental encouragement for researchers to use open ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peer Review
Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review methods are used to maintain quality standards, improve performance, and provide credibility. In academia, scholarly peer review is often used to determine an academic paper's suitability for publication. Peer review can be categorized by the type of activity and by the field or profession in which the activity occurs, e.g., medical peer review. It can also be used as a teaching tool to help students improve writing assignments. Henry Oldenburg (1619–1677) was a German-born British philosopher who is seen as the 'father' of modern scientific peer review. Professional Professional peer review focuses on the performance of professionals, with a view to improving quality, upholding standards, or providing certification. In academia, peer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patentability
Within the context of a national or multilateral body of law, an invention is patentable if it meets the relevant legal conditions to be granted a patent. By extension, patentability also refers to the substantive conditions that must be met for a patent to be held valid. Requirements The patent laws usually require that, for an invention to be patentable, it must be: * Patentable subject matter, i.e., a kind of subject-matter eligible for patent protection * Novel (i.e. at least some aspect of it must be new) * Non-obvious (in United States patent law) or involve an inventive step (in European patent law) * Useful (in U.S. patent law) or be susceptible of industrial application (in European patent law) Usually the term "''patentability''" only refers to "substantive" conditions, and does not refer to formal conditions such as the " sufficiency of disclosure", the "unity of invention" or the " best mode requirement". Judging patentability is one aspect of the official ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Data Theft
Data theft is a growing phenomenon primarily caused by system administrators and office workers with access to technology such as database servers, desktop computers and a growing list of hand-held devices capable of storing digital information, such as USB flash drives, iPods and even digital cameras. Since employees often spend a considerable amount of time developing contacts, confidential, and copyrighted information for the company they work for, they may feel they have some right to the information and are inclined to copy and/or delete part of it when they leave the company, or misuse it while they are still in employment. Information can be sold and bought and then used by criminals and criminal organizations. Alternatively, an employee may choose to deliberately abuse trusted access to information for the purpose of exposing misconduct by the employer. From the perspective of the society, such an act of whistleblowing can be seen as positive and is protected by law in certa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Provenance
Provenance (from the French ''provenir'', 'to come from/forth') is the chronology of the ownership, custody or location of a historical object. The term was originally mostly used in relation to works of art but is now used in similar senses in a wide range of fields, including archaeology, paleontology, archives, manuscripts, printed books, the circular economy, and science and computing. The primary purpose of tracing the provenance of an object or entity is normally to provide contextual and circumstantial evidence for its original production or discovery, by establishing, as far as practicable, its later history, especially the sequences of its formal ownership, custody and places of storage. The practice has a particular value in helping Authentication, authenticate objects. Comparative techniques, expert opinions and the results of scientific tests may also be used to these ends, but establishing provenance is essentially a matter of documentation. The term dates to the 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Visualized Experiments
The ''Journal of Visualized Experiments'' (styled ''JoVE'') is a peer-reviewed scientific journal that publishes experimental methods in video format. The journal is based in Cambridge, MA and was established in December 2006. Moshe Pritsker is the CEO and co-founder. Abstracting and indexing ''JoVE'' is abstracted and indexed in Index Medicus, MEDLINE/PubMed, BIOSIS Previews, and Science Citation Index Expanded. According to the ''Journal Citation Reports'', the journal had a 2020 impact factor of 1.4. Format and scope ''JoVE'' covers research methods and experimental techniques from both the physical and life sciences. The journal currently has 13 sections: Biology, Developmental Biology, Neuroscience, Immunology and Infection, Medicine, Bioengineering, Engineering, Chemistry, Behavior, Environment, Biochemistry, Cancer Research, and Genetics. JoVE also publishes Science Education collections aimed at instructing scientists in fundamental concepts and methods in a range of fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ugi Reaction
The Ugi reaction is a multi-component reaction in organic chemistry involving a ketone or aldehyde, an amine, an isocyanide and a carboxylic acid to form a bis-amide. The reaction is named after Ivar Karl Ugi, who first reported this reaction in 1959. The Ugi reaction is exothermic and usually complete within minutes of adding the isocyanide. High concentration (0.5M - 2.0M) of reactants give the highest yields. Polar, aprotic solvents, like DMF, work well. However, methanol and ethanol have also been used successfully. This uncatalyzed reaction has an inherent high atom economy as only a molecule of water is lost, and the chemical yield in general is high. Several reviews have been published. Due to the reaction products being potential protein mimetics there have been many attempts to development an enantioselective Ugi reaction, the first successful report of which was in 2018. Reaction mechanism One plausible reaction mechanism is depicted below: Amine 1 and ketone ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of East Anglia
The University of East Anglia (UEA) is a public research university in Norwich, England. Established in 1963 on a campus west of the city centre, the university has four faculties and 26 schools of study. The annual income of the institution for 2020–21 was £292.1 million, of which £35.2 million was from research grants and contracts, with an expenditure of £290.4 million, and had an undergraduate offer rate of 85.1% in 2021. UEA alumni and faculty include three Nobel laureates, a discoverer of Hepatitis C and of the Hepatitis D genome, a lead developer of the Oxford–AstraZeneca COVID-19 vaccine, one President of the Royal Society, and at least 48 Fellows of the Royal Society. Alumni also include heads of state, government and intergovernmental organisations, as well as three Booker Prize winning authors. History 1960s People in Norwich began to talk about the possibility of setting up a university in the nineteenth century, and attempts to establish ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antony Garrett Lisi
Antony Garrett Lisi (born January 24, 1968), known as Garrett Lisi, is an American theoretical physicist. Lisi works as an independent researcher without an academic position. Lisi is known for " An Exceptionally Simple Theory of Everything," a paper proposing a unified field theory based on the E Lie group, combining particle physics with Einstein's theory of gravitation. The theory is incomplete and has unresolved problems. The theory has been extensively criticized in the scientific community. Biography Education and career Lisi was born in Los Angeles and raised in San Diego, California. He graduated from Cate School in 1987. Lisi went on to receive two B.S. degrees with highest honors in physics and mathematics from the University of California, Los Angeles, in 1991. Lisi received a Ph.D. in physics from the University of California, San Diego, in 1999. Lisi then left academia. In July 2006, Lisi was awarded an FQXi grant to conduct research in quantum mechanics and u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
OpenWetWare
OpenWetWare is a wiki whose mission is "to support open research, education, publication, and discussion in biological sciences and engineering." OpenWetWare was created by graduate students at MIT on April 20, 2005. Initially, it served as a private lab wiki for the labs of Drew Endy and Tom Knight at MIT. The site was opened up to allow any lab to join on June 22, 2005. As of April 6, 2007 the site hosted 100 research laboratories from over 40 institutions, including Boston University, Brown University, Caltech, Cambridge Research Institute, CNRS, Duke University, and many others. In addition to laboratories, a number of scientific communities are based on the site, including synthetic biology, Mimulus, and the BioBricks Foundation. One scientific community is the iGEM community with over 60 different teams represented on June 28, 2013, including the NRP-UEA-Norwich team and the Groningen team. OpenWetWare runs on MediaWiki software on Linux servers. All content is availab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vinod Scaria
Dr. Vinod Scaria FRSB, FRSPH (born 9 March 1981) is an Indian biologist, medical researcher pioneering in Precision Medicine and Clinical Genomics in India. He is best known for sequencing the first Indian genome. He was also instrumental in the sequencing of The first Sri Lankan Genome, analysis of the first Malaysian Genome sequencing and analysis of the Wild-type strain of Zebrafish and the IndiGen programme on Genomics for Public Health in India He is presently a scientist at CSIR Institute of Genomics and Integrative Biology and an adjunct faculty at Indraprastha Institute of Information Technology, Delhi. He along with his colleague and collaborator Sridhar Sivasuubu are widely regarded as the pioneers in the area of clinical genomics in India. They are also the co-founders of the Genomics for Understanding Rare Diseases India Alliance Network (GUaRDIAN) a large clinical network working in the area of Rare Disease Genomics in India. They were also instrumental in setting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
