One Little Pill
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One Little Pill
''One Little Pill'' is a documentary film about the use of generic medications (primarily naltrexone, but also nalmefene) for treating and curing alcoholism. The primary focus is on the so-called Sinclair method, which pairs these medications with continued drinking. It was produced by Zard Productions as a film project for the C Three Foundation and released on Vimeo and VHX for on-demand viewing in October 2014. As of August 2015, DVD-R copies are also available. Synopsis ''One Little Pill'' is a documentary film about the Sinclair method of treating alcohol abuse. The film follows the lives of several people who have suffered from alcoholism, and have been helped by the treatment. Perspectives from scientists, treatment centers, doctors, and a legal prosecutor are also presented. The film describes the application of opioid blockers (naltrexone or nalmefene) as an alternative to help alcohol addicts in place of other more mainstream solutions such as twelve-step pro ...
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Claudia Christian
Claudia Christian (born Claudia Ann Coghlan August 10, 1965) is an American actress, singer and author, known for her roles as Commander Susan Ivanova on '' Babylon 5'', as Captain Maynard on Fox's ''9-1-1'', and as the voice of Hera on the Netflix series '' Blood of Zeus''. She is also the voice of Helga Sinclair in ''Atlantis: The Lost Empire.'' She is the founder and CEO of the C Three Foundation, a proponent of the medication based Sinclair Method for treating alcohol dependence. Early life Christian was born in Glendale, California, the only daughter of Hildegard (''née'' Christian), who worked as the director of Giorgio Beverly Hills, and James Michael Coghlan. Her mother is from Germany and her father has Irish ancestry. Christian and her three elder brothers were raised in Connecticut. Her eldest brother was killed by a drunk driver while the family lived in Houston, Texas, and the family moved to California when she was 14. She changed her name by deed poll from Co ...
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Naltrexone
Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found to be effective in the treatment of other addictions and may be used for them off-label. An opioid-dependent person should not receive naltrexone before detoxification. It is taken by mouth or by injection into a muscle. Effects begin within 30 minutes. A decreased desire for opioids may take a few weeks to occur. Side effects may include trouble sleeping, anxiety, nausea, and headaches. In those still on opioids, opioid withdrawal may occur. Use is not recommended in people with liver failure. It is unclear if use is safe during pregnancy. Naltrexone is an opioid antagonist and works by blocking the effects of opioids, including both opioid drugs as well as opioids naturally produced in the brain. Naltrexone was first made in 1965 and ...
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Nalmefene
Nalmefene is an opioid antagonist medication used in the management of opioid overdose and alcohol dependence. It is taken by mouth. Nalmefene is an opiate derivative similar in both structure and activity to the opioid antagonist naltrexone. Advantages of nalmefene relative to naltrexone include a longer elimination half-life, greater oral bioavailability, and no observed dose-dependent liver toxicity. Nalmefene may precipitate acute withdrawal symptoms in people who are dependent on opioid drugs, or more rarely when used post-operatively, to counteract the effects of strong opioids used in surgery. Nalmefene is available as a generic medication. Medical uses Opioid overdose Intravenous doses of nalmefene have been shown effective at counteracting the respiratory depression produced by opioid overdose. Alcohol dependence Nalmefene is used in the European Union to reduce alcohol dependence and NICE recommends the use of nalmefene to reduce alcohol consumption in combinati ...
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Alcoholism
Alcoholism is, broadly, any drinking of alcohol (drug), alcohol that results in significant Mental health, mental or physical health problems. Because there is disagreement on the definition of the word ''alcoholism'', it is not a recognized diagnostic entity. Predominant diagnostic classifications are alcohol use disorder (DSM-5) or alcohol dependence (ICD-11); these are defined in their respective sources. Excessive alcohol use can damage all organ systems, but it particularly affects the brain, heart, liver, pancreas and immune system. Alcoholism can result in mental illness, delirium tremens, Wernicke–Korsakoff syndrome, Heart arrhythmia, irregular heartbeat, an impaired immune response, liver cirrhosis and alcohol and cancer, increased cancer risk. Drinking during pregnancy can result in fetal alcohol spectrum disorders. Women are generally more sensitive than men to the harmful effects of alcohol, primarily due to their smaller body weight, lower capacity to metaboli ...
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DVD-R
DVD recordable and DVD rewritable are optical disc recording technologies. Both terms describe DVD optical discs that can be written to by a DVD recorder, whereas only 'rewritable' discs are able to erase and rewrite data. Data is written ('burned') to the disc by a laser, rather than the data being 'pressed' onto the disc during manufacture, like a DVD-ROM. Pressing is used in mass production, primarily for the distribution of home video. Like CD-Rs, DVD recordable uses dye to store the data. During the burning of a single bit, the laser's intensity affects the reflective properties of the burned dye. By varying the laser intensity quickly, high density data is written in precise tracks. Since written tracks are made of darkened dye, the data side of a recordable DVD has a distinct color. Burned DVDs have a higher failure-to-read rate than pressed DVDs, due to differences in the reflective properties of dye compared to the aluminum substrate of pressed discs. Comparing recordab ...
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Alcohol Abuse
Alcohol abuse encompasses a spectrum of unhealthy alcohol drinking behaviors, ranging from binge drinking to alcohol dependence, in extreme cases resulting in health problems for individuals and large scale social problems such as alcohol-related crimes. Alcohol abuse was a psychiatric diagnosis in the DSM-IV, and has been merged with alcohol dependence into alcohol use disorder in the DSM-5. Globally, excessive alcohol consumption is the seventh leading risk factor for both death and the burden of disease and injury. In short, except for tobacco, alcohol accounts for a higher burden of disease than any other drug. Alcohol use is a major cause of preventable liver disease worldwide, and alcoholic liver disease is the main alcohol-related chronic medical illness. Millions of people of all ages, from adolescents to the elderly, engage in unhealthy drinking. Alcohol use disorder can affect people from all walks of life. There are many factors that play a role in causing someone to ...
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Twelve-step Program
Twelve-step programs are international mutual aid programs supporting recovery from substance addictions, behavioral addictions and compulsions. Developed in the 1930s, the first twelve-step program, Alcoholics Anonymous (AA), aided its membership to overcome alcoholism. Since that time dozens of other organizations have been derived from AA's approach to address problems as varied as drug addiction, compulsive gambling, sex, and overeating. All twelve-step programs utilize a version of AA's suggested twelve steps first published in the 1939 book '' Alcoholics Anonymous: The Story of How More Than One Hundred Men Have Recovered from Alcoholism.'' As summarized by the American Psychological Association (APA), the process involves the following: * admitting that one cannot control one's alcoholism, addiction, or compulsion; * coming to believe in a Higher Power that can give strength; * examining past errors with the help of a sponsor (experienced member); * making amends for the ...
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Sinclair Method
Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found to be effective in the treatment of other addictions and may be used for them off-label. An opioid-dependent person should not receive naltrexone before detoxification. It is taken by mouth or by injection into a muscle. Effects begin within 30 minutes. A decreased desire for opioids may take a few weeks to occur. Side effects may include trouble sleeping, anxiety, nausea, and headaches. In those still on opioids, opioid withdrawal may occur. Use is not recommended in people with liver failure. It is unclear if use is safe during pregnancy. Naltrexone is an opioid antagonist and works by blocking the effects of opioids, including both opioid drugs as well as opioids naturally produced in the brain. Naltrexone was first made in 1965 and w ...
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Alcoholism
Alcoholism is, broadly, any drinking of alcohol (drug), alcohol that results in significant Mental health, mental or physical health problems. Because there is disagreement on the definition of the word ''alcoholism'', it is not a recognized diagnostic entity. Predominant diagnostic classifications are alcohol use disorder (DSM-5) or alcohol dependence (ICD-11); these are defined in their respective sources. Excessive alcohol use can damage all organ systems, but it particularly affects the brain, heart, liver, pancreas and immune system. Alcoholism can result in mental illness, delirium tremens, Wernicke–Korsakoff syndrome, Heart arrhythmia, irregular heartbeat, an impaired immune response, liver cirrhosis and alcohol and cancer, increased cancer risk. Drinking during pregnancy can result in fetal alcohol spectrum disorders. Women are generally more sensitive than men to the harmful effects of alcohol, primarily due to their smaller body weight, lower capacity to metaboli ...
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Naltrexone
Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found to be effective in the treatment of other addictions and may be used for them off-label. An opioid-dependent person should not receive naltrexone before detoxification. It is taken by mouth or by injection into a muscle. Effects begin within 30 minutes. A decreased desire for opioids may take a few weeks to occur. Side effects may include trouble sleeping, anxiety, nausea, and headaches. In those still on opioids, opioid withdrawal may occur. Use is not recommended in people with liver failure. It is unclear if use is safe during pregnancy. Naltrexone is an opioid antagonist and works by blocking the effects of opioids, including both opioid drugs as well as opioids naturally produced in the brain. Naltrexone was first made in 1965 and ...
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2014 Documentary Films
Fourteen or 14 may refer to: * 14 (number), the natural number following 13 and preceding 15 * one of the years 14 BC, AD 14, 1914, 2014 Music * 14th (band), a British electronic music duo * ''14'' (David Garrett album), 2013 *''14'', an unreleased album by Charli XCX * "14" (song), 2007, from ''Courage'' by Paula Cole Other uses * ''Fourteen'' (film), a 2019 American film directed by Dan Sallitt * ''Fourteen'' (play), a 1919 play by Alice Gerstenberg * ''Fourteen'' (manga), a 1990 manga series by Kazuo Umezu * ''14'' (novel), a 2013 science fiction novel by Peter Clines * ''The 14'', a 1973 British drama film directed by David Hemmings * Fourteen, West Virginia, United States, an unincorporated community * Lot Fourteen, redevelopment site in Adelaide, South Australia, previously occupied by the Royal Adelaide Hospital * "The Fourteen", a nickname for NASA Astronaut Group 3 * Fourteen Words, a phrase used by white supremacists and Nazis See also * 1/4 (other) * ...
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