Optimal Virulence
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Optimal Virulence
Optimal virulence is a concept relating to the ecology of hosts and parasites. One definition of virulence is the host's parasite-induced loss of fitness. The parasite's fitness is determined by its success in transmitting offspring to other hosts. For about 100 years, the consensus was that virulence decreased and parasitic relationships evolved toward symbiosis. This was even called the law of declining virulence despite being a hypothesis, not even a theory. It has been challenged since the 1980s and has been disproved. A pathogen that is too restrained will lose out in competition to a more aggressive strain that diverts more host resources to its own reproduction. However, the host, being the parasite's resource and habitat in a way, suffers from this higher virulence. This might induce faster host death, and act against the parasite's fitness by reducing probability to encounter another host (killing the host too fast to allow for transmission). Thus, there is a natural fo ...
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Ecology
Ecology () is the study of the relationships between living organisms, including humans, and their physical environment. Ecology considers organisms at the individual, population, community, ecosystem, and biosphere level. Ecology overlaps with the closely related sciences of biogeography, evolutionary biology, genetics, ethology, and natural history. Ecology is a branch of biology, and it is not synonymous with environmentalism. Among other things, ecology is the study of: * The abundance, biomass, and distribution of organisms in the context of the environment * Life processes, antifragility, interactions, and adaptations * The movement of materials and energy through living communities * The successional development of ecosystems * Cooperation, competition, and predation within and between species * Patterns of biodiversity and its effect on ecosystem processes Ecology has practical applications in conservation biology, wetland management, natural resource managemen ...
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Spanish Flu
The 1918–1920 influenza pandemic, commonly known by the misnomer Spanish flu or as the Great Influenza epidemic, was an exceptionally deadly global influenza pandemic caused by the H1N1 influenza A virus. The earliest documented case was March 1918 in Kansas, United States, with further cases recorded in France, Germany and the United Kingdom in April. Two years later, nearly a third of the global population, or an estimated 500 million people, had been infected in four successive waves. Estimates of deaths range from 17 million to 50 million, and possibly as high as 100 million, making it one of the deadliest pandemics in history. The pandemic broke out near the end of World War I, when wartime censors suppressed bad news in the belligerent countries to maintain morale, but newspapers freely reported the outbreak in neutral Spain, creating a false impression of Spain as the epicenter and leading to the "Spanish flu" misnomer. Limited historical epidemiological ...
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Sanitation
Sanitation refers to public health conditions related to clean drinking water and treatment and disposal of human excreta and sewage. Preventing human contact with feces is part of sanitation, as is hand washing with soap. Sanitation systems aim to protect human health by providing a clean environment that will stop the transmission of disease, especially through the fecal–oral route.SuSanA (2008)Towards more sustainable sanitation solutions Sustainable Sanitation Alliance (SuSanA) For example, diarrhea, a main cause of malnutrition and stunted growth in children, can be reduced through adequate sanitation. There are many other diseases which are easily transmitted in communities that have low levels of sanitation, such as ascariasis (a type of intestinal worm infection or helminthiasis), cholera, hepatitis, polio, schistosomiasis, and trachoma, to name just a few. A range of sanitation technologies and approaches exists. Some examples are community-led total sanitation ...
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Hygiene
Hygiene is a series of practices performed to preserve health. According to the World Health Organization (WHO), "Hygiene refers to conditions and practices that help to maintain health and prevent the spread of diseases." Personal hygiene refers to maintaining the body's cleanliness. Hygiene activities can be grouped into the following: home and everyday hygiene, personal hygiene, medical hygiene, sleep hygiene and food hygiene. Home and every day hygiene includes hand washing, respiratory hygiene, food hygiene at home, hygiene in the kitchen, hygiene in the bathroom, laundry hygiene and medical hygiene at home. Many people equate hygiene with 'cleanliness,' but hygiene is a broad term. It includes such personal habit choices as how frequently to take a shower or bath, wash hands, trim fingernails, and wash clothes. It also includes attention to keeping surfaces in the home and workplace clean, including bathroom facilities. Some regular hygiene practices may be considered good ...
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Immune
In biology, immunity is the capability of multicellular organisms to resist harmful microorganisms. Immunity involves both specific and nonspecific components. The nonspecific components act as barriers or eliminators of a wide range of pathogens irrespective of their antigenic make-up. Other components of the immune system adapt themselves to each new disease encountered and can generate pathogen-specific immunity. Immunity is a complex biological system that can recognize and tolerate whatever belongs to the self, and to recognize and reject what is foreign (non-self). Innate and adaptive Innate Immunity First off, the immune system is a system in the body of animals that enables animals to avoid or limit many infections caused by pathogens. Pathogens are disease causing agents, causing a wide range of illnesses. As for Diseases it's when structure of an organism is negatively affected other than external injury. Both diseases and pathogens affect the immune system causing ill ...
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Antagonistic Pleiotropy
The antagonistic pleiotropy hypothesis was first proposed by George C. Williams in 1957 as an evolutionary explanation for senescence. Pleiotropy is the phenomenon where one gene controls for more than one phenotypic trait in an organism. Antagonistic pleiotropy is when one gene controls for more than one trait, where at least one of these traits is beneficial to the organism's fitness early on in life and at least one is detrimental to the organism's fitness later on due to a decline in the force of natural selection. The theme of G.C. William's idea about antagonistic pleiotropy was that if a gene caused both increased reproduction in early life and aging in later life, then senescence would be adaptive in evolution. For example, one study suggests that since follicular depletion in human females causes both more regular cycles in early life and loss of fertility later in life through menopause, it can be selected for by having its early benefits outweigh its late costs.Wood, J ...
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Happenstance
Happenstance, a portmanteau of ''happening'' and ''circumstance'', may refer to: Film and TV * ''Happenstance'' (film), a 2000 French film by Laurent Firode * "Happenstance" (CSI), a season seven episode of the American crime drama ''CSI'' Music * ''Happenstance'' (Fozzy album), a 2002 album * ''Happenstance'' (Rachael Yamagata album), a 2004 album *"Happenstance", a song by The dB's from their 1982 album '' Repercussion'' *"Happenstance", a song by Miles Kane from the album ''Colour of the Trap'' Other *''Happenstance'', a novel by Canadian author Carol Shields Carol Ann Shields, (née Warner; June 2, 1935 – July 16, 2003) was an American-born Canadian novelist and short story writer. She is best known for her 1993 novel '' The Stone Diaries'', which won the U.S. Pulitzer Prize for Fiction as well a ...
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Clostridium Tetani
''Clostridium tetani'' is a common soil bacterium and the causative agent of tetanus. Vegetative cells of ''Clostridium tetani'' are usually rod-shaped and up to 2.5 μm long, but they become enlarged and tennis racket- or drumstick-shaped when forming spores. ''C. tetani'' spores are extremely hardy and can be found globally in soil or in the gastrointestinal tract of animals. If inoculated into a wound, ''C. tetani'' can grow and produce a potent toxin, tetanospasmin, which interferes with motor neurons, causing tetanus. The toxin's action can be prevented with tetanus toxoid vaccines, which are often administered to children worldwide. Characteristics ''Clostridium tetani'' is a rod-shaped, Gram-positive bacterium, typically up to 0.5 μm wide and 2.5 μm long. It is motile by way of various flagella that surround its body. ''C. tetani'' cannot grow in the presence of oxygen. It grows best at temperatures ranging from 33 to 37°C. Upon exposure to various conditions, ''C. ...
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Tetanus
Tetanus, also known as lockjaw, is a bacterial infection caused by ''Clostridium tetani'', and is characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body. Each spasm usually lasts a few minutes. Spasms occur frequently for three to four weeks. Some spasms may be severe enough to fracture bones. Other symptoms of tetanus may include fever, sweating, headache, trouble swallowing, high blood pressure, and a fast heart rate. Onset of symptoms is typically three to twenty-one days following infection. Recovery may take months. About ten percent of cases prove to be fatal. ''C. tetani'' is commonly found in soil, saliva, dust, and manure. The bacteria generally enter through a break in the skin such as a cut or puncture wound by a contaminated object. They produce toxins that interfere with normal muscle contractions. Diagnosis is based on the presenting signs and symptoms. The disease does not spread between pe ...
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Philosophical Transactions Of The Royal Society B
''Philosophical Transactions of the Royal Society B: Biological Sciences'' is a biweekly peer-reviewed scientific journal published by the Royal Society. The editor-in-chief is John Pickett (Cardiff University). Overview Each issue covers a specific area of the biological sciences. Each issue aims to create an original and authoritative synthesis, often bridging traditional disciplines, which showcases current developments and provides a foundation for future research, applications and policy decisions. Each issue is edited by one or more expert guest editors. The themes fall into one of four general categories: * Cell and Development * Health and Disease * Environment and Evolution * Neuroscience and Cognition All articles become freely accessible one year after their publication date. History ''Philosophical Transactions of the Royal Society'' was established in 1665 by the Royal Society and is the oldest scientific journal in the English-speaking world. Henry Oldenburg ...
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Ultimate Causes
A proximate cause is an event which is ''closest'' to, or immediately responsible for causing, some observed result. This exists in contrast to a higher-level ultimate cause (or ''distal cause'') which is usually thought of as the "real" reason something occurred. * ''Example:'' Why did the ship sink? ** Proximate cause: Because it was holed beneath the waterline, water entered the hull and the ship became denser than the water which supported it, so it could not stay afloat. ** Ultimate cause: Because the ship hit a rock which tore open the hole in the ship's hull. In most situations, an ultimate cause may itself be a proximate cause in comparison to a further ultimate cause. Hence we can continue the above example as follows: * ''Example:'' Why did the ship hit the rock? ** Proximate cause: Because the ship failed to change course to avoid it. ** Ultimate cause: Because the ship was under autopilot and the autopilot's data was inaccurate. ** (even stronger): Because the ship ...
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Life History Theory
Life history theory is an analytical frameworkVitzthum, V. (2008). Evolutionary models of women's reproductive functioning. ''Annual Review of Anthropology'', ''37'', 53-73 designed to study the diversity of life history strategies used by different organisms throughout the world, as well as the causes and results of the variation in their life cycles.Flatt, T., & Heyland, A. (Eds.). (2011). Mechanisms of Life History Evolution : The Genetics and Physiology of Life History Traits and Trade-Offs. Oxford, GB: OUP Oxford. It is a theory of biological evolution that seeks to explain aspects of organisms' anatomy and behavior by reference to the way that their life histories—including their reproductive development and behaviors, post-reproductive behaviors, and lifespan (length of time alive)—have been shaped by natural selection. A life history strategy is the "age- and stage-specific patterns" and timing of events that make up an organism's life, such as birth, weaning, maturation, ...
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