Nuclear Groove
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Nuclear Groove
A nuclear groove is an invagination of the nuclear envelope, in the Anatomical terms of location#Axes, longitudinal axis. It can be present in: *Thyroid neoplasms: It is a characteristic feature of papillary thyroid carcinoma, but has also been seen in other types of thyroid neoplasms, as well as in non-neoplastic thyroid lesions. *Ovarian tumors including Brenner tumors, adult granulosa cell tumors, and transitional cell tumors. *Breast carcinomas *Vaginal, cervix, cervical and/or endometrial neoplasms *Papillary neoplasms of several organs: papillary transitional cell carcinoma of the urinary bladder, papillary renal cell carcinoma, papillary endometrioid carcinoma of the prostate, in thymic carcinomas, and in non-epithelial tumors. References

{{reflist Histopathology ...
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Nuclear Grooves
Nuclear may refer to: Physics Relating to the Atomic nucleus, nucleus of the atom: *Nuclear engineering *Nuclear physics *Nuclear power *Nuclear reactor *Nuclear weapon *Nuclear medicine *Radiation therapy *Nuclear warfare Mathematics *Nuclear space *Nuclear operator *Nuclear congruence *Nuclear C*-algebra Biology Relating to the Cell nucleus, nucleus of the cell: * Nuclear DNA Society *Nuclear family, a family consisting of a pair of adults and their children Music *Nuclear (band), "Nuclear" (band), group music. *Nuclear (Ryan Adams song), "Nuclear" (Ryan Adams song), 2002 *"Nuclear", a song by Mike Oldfield from his ''Man on the Rocks'' album *Nu.Clear (EP), ''Nu.Clear'' (EP) by South Korean girl group CLC See also

*Nucleus (other) *Nucleolus *Nucleation *Nucleic acid *Nucular * * {{Disambiguation ...
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Vagina
In mammals, the vagina is the elastic, muscular part of the female genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen. At the deep end, the cervix (neck of the uterus) bulges into the vagina. The vagina allows for sexual intercourse and birth. It also channels menstrual flow, which occurs in humans and closely related primates as part of the menstrual cycle. Although research on the vagina is especially lacking for different animals, its location, structure and size are documented as varying among species. Female mammals usually have two external openings in the vulva; these are the urethral opening for the urinary tract and the vaginal opening for the genital tract. This is different from male mammals, who usually have a single urethral opening for both urination and reproduction. The vaginal opening is much larger than the nearby urethral opening, an ...
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Prostate
The prostate is both an Male accessory gland, accessory gland of the male reproductive system and a muscle-driven mechanical switch between urination and ejaculation. It is found only in some mammals. It differs between species anatomically, chemically, and physiologically. Anatomically, the prostate is found below the Urinary bladder, bladder, with the urethra passing through it. It is described in gross anatomy as consisting of lobes and in microanatomy by zone. It is surrounded by an elastic, fibromuscular capsule and contains glandular tissue as well as connective tissue. The prostate glands produce and contain fluid that forms part of semen, the substance emitted during ejaculation as part of the male Human sexual response cycle, sexual response. This prostatic fluid is slightly alkaline, milky or white in appearance. The alkalinity of semen helps neutralize the acidity of the vagina, vaginal tract, prolonging the lifespan of sperm. The prostatic fluid is expelled in the ...
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Papillary Endometrioid Carcinoma
Papilla (Latin, 'nipple') or papillae may refer to: In animals * Papilla (fish anatomy), in the mouth of fish * Basilar papilla, a sensory organ of lizards, amphibians and fish * Dental papilla, in a developing tooth * Dermal papillae, part of the skin * Major duodenal papilla, in the duodenum * Minor duodenal papilla, in the duodenum * Genital papilla, a feature of the external genitalia of some animals * Interdental papilla, part of the gums * Lacrimal papilla, on the bottom eyelid * Lingual papillae, small structures on the upper surface of the tongue * Renal papilla, part of the kidney In plants and fungi * Papilla (mycology), a nipple-shaped protrusion in the center of the cap * Stigmatic papilla, part of the stigma (botany) See also * * * Blister, a small pocket of body fluid within the upper layers of the skin * Papillary muscle, a muscle in the heart * Papilloma, a benign epithelial tumor * Papule A papule is a small, well-defined bump in the skin. It may have a rou ...
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Papillary Renal Cell Carcinoma
Papillary renal cell carcinoma (PRCC) is a malignant, heterogeneous tumor originating from renal tubular epithelial cells of the kidney, which comprises approximately 10-15% of all kidney neoplasms. Based on its morphological features, PRCC can be classified into two main subtypes, which are type 1 (basophilic) and type 2 (eosinophilic). As with other types of renal cell cancer, most cases of PRCC are discovered incidentally without showing specific signs or symptoms of cancer. In advanced stages, hematuria, flank pain, and abdominal mass are the three classic manifestation. While a complete list of the causes of PRCC remains unclear, several risk factors were identified to affect PRCC development, such as genetic mutations, kidney-related disease, environmental and lifestyle risk factors. For pathogenesis, type 1 PRCC is mainly caused by MET gene mutation while type 2 PRCC is associated with several different genetic pathways. For diagnosis, PRCC is detectable through computed to ...
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Urinary Bladder
The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra. The typical adult human bladder will hold between 300 and (10.14 and ) before the urge to empty occurs, but can hold considerably more. The Latin phrase for "urinary bladder" is ''vesica urinaria'', and the term ''vesical'' or prefix ''vesico -'' appear in connection with associated structures such as vesical veins. The modern Latin word for "bladder" – ''cystis'' – appears in associated terms such as cystitis (inflammation of the bladder). Structure In humans, the bladder is a hollow muscular organ situated at the base of the pelvis. In gross anatomy, the bladder can be divided into a broad , a body, an apex, and a neck. The apex (also called the vertex) is directed forward ...
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Papillary Transitional Cell Carcinoma
Papilla (Latin, 'nipple') or papillae may refer to: In animals * Papilla (fish anatomy), in the mouth of fish * Basilar papilla, a sensory organ of lizards, amphibians and fish * Dental papilla, in a developing tooth * Dermal papillae, part of the skin * Major duodenal papilla, in the duodenum * Minor duodenal papilla, in the duodenum * Genital papilla, a feature of the external genitalia of some animals * Interdental papilla, part of the gums * Lacrimal papilla, on the bottom eyelid * Lingual papillae, small structures on the upper surface of the tongue * Renal papilla, part of the kidney In plants and fungi * Papilla (mycology), a nipple-shaped protrusion in the center of the cap * Stigmatic papilla, part of the stigma (botany) See also * * * Blister, a small pocket of body fluid within the upper layers of the skin * Papillary muscle, a muscle in the heart * Papilloma, a benign epithelial tumor * Papule A papule is a small, well-defined bump in the skin. It may have a rou ...
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Papillary Neoplasm
Papilla (Latin, 'nipple') or papillae may refer to: In animals * Papilla (fish anatomy), in the mouth of fish * Basilar papilla, a sensory organ of lizards, amphibians and fish * Dental papilla, in a developing tooth * Dermal papillae, part of the skin * Major duodenal papilla, in the duodenum * Minor duodenal papilla, in the duodenum * Genital papilla, a feature of the external genitalia of some animals * Interdental papilla, part of the gums * Lacrimal papilla, on the bottom eyelid * Lingual papillae, small structures on the upper surface of the tongue * Renal papilla, part of the kidney In plants and fungi * Papilla (mycology), a nipple-shaped protrusion in the center of the cap * Stigmatic papilla, part of the stigma (botany) See also * * * Blister, a small pocket of body fluid within the upper layers of the skin * Papillary muscle, a muscle in the heart * Papilloma, a benign epithelial tumor * Papule A papule is a small, well-defined bump in the skin. It may have a rou ...
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Endometrial Neoplasm
The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus. It has a basal layer and a functional layer: the basal layer contains stem cells which regenerate the functional layer. The functional layer thickens and then is shed during menstruation in humans and some other mammals, including apes, Old World monkeys, some species of bat, the elephant shrew and the Cairo spiny mouse. In most other mammals, the endometrium is reabsorbed in the estrous cycle. During pregnancy, the glands and blood vessels in the endometrium further increase in size and number. Vascular spaces fuse and become interconnected, forming the placenta, which supplies oxygen and nutrition to the embryo and fetus.Blue Histology - Female Reproductive System
. School of An ...
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Cervix
The cervix or cervix uteri (Latin, 'neck of the uterus') is the lower part of the uterus (womb) in the human female reproductive system. The cervix is usually 2 to 3 cm long (~1 inch) and roughly cylindrical in shape, which changes during pregnancy. The narrow, central cervical canal runs along its entire length, connecting the uterine cavity and the lumen of the vagina. The opening into the uterus is called the internal os, and the opening into the vagina is called the external os. The lower part of the cervix, known as the vaginal portion of the cervix (or ectocervix), bulges into the top of the vagina. The cervix has been documented anatomically since at least the time of Hippocrates, over 2,000 years ago. The cervical canal is a passage through which sperm must travel to fertilize an egg cell after sexual intercourse. Several methods of contraception, including cervical caps and cervical diaphragms, aim to block or prevent the passage of sperm through the cervical ...
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Breast Carcinoma
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with Metastatic breast cancer, distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or jaundice, yellow skin. Risk factors for developing breast cancer include obesity, a Lethargy, lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at menarche, first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly ...
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Cytopathology Of Papillary Thyroid Carcinoma
Cytopathology (from Greek , ''kytos'', "a hollow"; , ''pathos'', "fate, harm"; and , ''-logia'') is a branch of pathology that studies and diagnoses diseases on the cellular level. The discipline was founded by George Nicolas Papanicolaou in 1928. Cytopathology is generally used on samples of free cells or tissue fragments, in contrast to histopathology, which studies whole tissues. Cytopathology is frequently, less precisely, called "cytology", which means "the study of cells". Cytopathology is commonly used to investigate diseases involving a wide range of body sites, often to aid in the diagnosis of cancer but also in the diagnosis of some infectious diseases and other inflammatory conditions. For example, a common application of cytopathology is the Pap smear, a screening tool used to detect precancerous cervical lesions that may lead to cervical cancer. Cytopathologic tests are sometimes called smear tests because the samples may be smeared across a glass microscope slide ...
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