|
C3-convertase
C3 convertase (''C4bC2b'', formerly ''C4b2a'') belongs to family of serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis. C3 convertase can be used to refer to the form produced in the alternative pathway (C3bBb) or the classical and lectin pathways (C4bC2b, formerly C4b2a). Once formed, both C3 convertases will catalyze the proteolytic cleavage of C3 into C3a and C3b (hence the name "C3-convertase"). The smaller fragment called C3a serves to increase vascular permeability and promote extravasation of phagocytes, while the larger C3b fragment can be used as an opsonin or bind to either type of C3 convertase to form the trimolecular C5 convertase to activate C5 for the membrane attack complex. Formation C3 convertase formation can occur in three different pathways: the classical, lectin, and alternative pathways. Alter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Complement Component 3
Complement component 3, often simply called C3, is a protein of the immune system. It plays a central role in the complement system and contributes to innate immunity. In humans it is encoded on chromosome 19 by a gene called ''C3''. Function C3 plays a central role in the activation of the complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. One form of C3-convertase, also known as C4b2a, is formed by a heterodimer of activated forms of C4 and C2. It catalyzes the proteolytic cleavage of C3 into C3a and C3b, generated during activation through the classical pathway as well as the lectin pathway. C3a is an anaphylotoxin and the precursor of some cytokines such as ASP, and C3b serves as an opsonizing agent. Factor I can cleave C3b into C3c and C3d, the latter of which plays a role in enhancing B cell responses. In the alternative complement pathway, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup C-M217
} Haplogroup C-M217, also known as C2 (and previously as C3), is a Y-chromosome DNA haplogroup. It is the most frequently occurring branch of the wider Haplogroup C (M130). It is found mostly in Central Asia, Eastern Siberia and significant frequencies in parts of East Asia and Southeast Asia including some populations in the Caucasus, Middle East, South Asia, East Europe. It is found in a much more widespread areas with a low frequency of less than 2%. The haplogroup C-M217 is now found at high frequencies among Central Asian peoples, indigenous Siberians, and some Native peoples of North America. In particular, males belonging to peoples such as the Buryats, Evens, Evenks, Itelmens, Kalmyks, Kazakhs, Koryaks, Mongolians, Negidals, Nivkhs, Udege, and Ulchi have high levels of M217. One particular haplotype within Haplogroup C2-M217 has received a great deal of attention, because of the possibility that it may represent direct patrilineal descent from Genghis Khan, thoug ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
C-3 (plastic Explosive)
C3, C-3, C.3, C03, C.III or C-III may refer to: Life and biology * C3 carbon fixation in plants * C3-convertase, an enzyme * Complement component 3, a protein of the innate immune system * Apolipoprotein C3, a human very low density lipoprotein * ATC code C03 ''Diuretics'', a subgroup of the Anatomical Therapeutic Chemical Classification System * Castavinol C3, a natural phenolic compound found in red wines * Cytochrome-c3 hydrogenase, an enzyme * Haplogroup C-M217, called C3 in older publications * In human anatomy, C3 may refer to: ** Cervical vertebra 3, one of the cervical vertebrae of the vertebral column ** Cervical spinal nerve 3 * Clinical Cell Culture, a medical technology company * C03, Malignant neoplasm of gum ICD-10 code * C3 Collaborating for Health, a health-promotion NGO * C3: an EEG electrode site according to the 10-20 system Military * C3, Command, control, and communications, a military concept * C-3 (plastic explosive), a plastic explosive related to C4 * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Type C3-class Ship
Type C3-class ships were the third type of cargo ship designed by the United States Maritime Commission (MARCOM) in the late 1930s. As it had done with the Type C1 ships and Type C2 ships, MARCOM circulated preliminary plans for comment. The design presented was not specific to any service or trade route, but was a general purpose ship that could be modified for specific uses. A total of 162 C3 ships were built from 1939 to 1946. The C3 was larger and faster than the C1 and C2 contemporaries, measuring from stem to stern (vs. for the C2), and designed to make (vs. for the C2). Like the C2, it had five cargo holds. A total of 465 of these ships were built between 1940 and 1947. A total of 75 ships were built with C3 hulls and engines, but not built as cargo ships. During World War II, many C3 ships were converted to naval uses, particularly as s, and as and s, ''Klondike''-class destroyer tenders, submarine tenders, and seaplane tenders. Ships in type *C3 DWT 12,595 as in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Command, Control, And Communications
Command and control (abbr. C2) is a "set of organizational and technical attributes and processes ... [that] employs human, physical, and information resources to solve problems and accomplish missions" to achieve the goals of an organization or enterprise, according to a 2015 definition by military scientists Marius Vassiliou, David S. Alberts, and Jonathan R. Agre. The term often refers to a military system. Versions of the United States Army List of United States Army Field Manuals, ''Field Manual 3-0'' circulated circa 1999 define C2 in a military organization as the exercise of authority and direction by a properly designated commanding officer over assigned and attached Armed forces, forces in the accomplishment of a Military operation, mission. A 1988 NATO definition is that command and control is the exercise of authority and direction by a properly designated individual over assigned resources in the accomplishment of a common goal. An Australian Defence Force definit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
C3 Carbon Fixation
carbon fixation is the most common of three metabolic pathways for carbon fixation in photosynthesis, along with and CAM. This process converts carbon dioxide and ribulose bisphosphate (RuBP, a 5-carbon sugar) into two molecules of 3-phosphoglycerate through the following reaction: :CO2 + H2O + RuBP → (2) 3-phosphoglycerate This reaction was first discovered by Melvin Calvin, Andrew Benson and James Bassham in 1950. C3 carbon fixation occurs in all plants as the first step of the Calvin–Benson cycle. (In and CAM plants, carbon dioxide is drawn out of malate and into this reaction rather than directly from the air.) Plants that survive solely on fixation ( plants) tend to thrive in areas where sunlight intensity is moderate, temperatures are moderate, carbon dioxide concentrations are around 200 ppm or higher, and groundwater is plentiful. The plants, originating during Mesozoic and Paleozoic eras, predate the plants and still represent approximately 95% of Eart ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apolipoprotein C3
Apolipoprotein C-III also known as apo-CIII, and apolipoprotein C3, is a protein that in humans is encoded by the ''APOC3'' gene. Apo-CIII is secreted by the liver as well as the small intestine, and is found on triglyceride-rich lipoproteins such as chylomicrons, very low density lipoprotein (VLDL), and remnant cholesterol. Structure ApoC-III is a relatively small protein containing 79 amino acids that can be glycosylated at threonine-74. The most abundant glycoforms are characterized by an O-linked disaccharide galactose linked to N-acetylgalactosamine (Gal- GalNAc), further modified with up to 2 sialic acid residues. Less abundant glycoforms are characterized by more complex and fucosylated glycan moieties. Function APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to inhibit hepatic uptake of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
C3 Collaborating For Health
C3 Collaborating for Health is a global, not-for-profit non-governmental organisation, based in London, that exists to find solutions to fight the epidemic of non-communicable diseases (NCDs). The C3 approach C3’s focus is on the main risk factors – tobacco use, physical inactivity, and poor diet (including the harmful use of alcohol) – which between them cause the majority of many of the major NCDs – cardiovascular disease (heart disease and stroke), type 2 diabetes, chronic lung disease and cancers. C3's work The United Nations Political Declaration on NCDs (September 2011) calls for a 'whole of society' approach to tackling NCDs. To this end, C3 works with a range of organisations that affect public health and prevention of NCDs, including health professionals and local community leaders, businesses, NGOs, researchers, planners and young people. * Health professionals and local communities: Health professionals, local health advocates and researchers are well place ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HMS C3
HMS ''C3'' was one of 38 C-class submarines built for the Royal Navy in the first decade of the 20th century. The boat was used to demolish a viaduct during the Zeebrugge Raid in 1918. Design and description The C class was essentially a repeat of the preceding B class, albeit with better performance underwater. The submarine had a length of overall, a beam of and a mean draft of . They displaced on the surface and submerged. The C-class submarines had a crew of two officers and fourteen ratings.Gardiner & Gray, p. 87 For surface running, the boats were powered by a single 16-cylinder Vickers petrol engine that drove one propeller shaft. When submerged the propeller was driven by a electric motor. They could reach on the surface and underwater. On the surface, the C class had a range of at . The boats were armed with two 18-inch (45 cm) torpedo tubes in the bow. They could carry a pair of reload torpedoes, but generally did not as they would have to remove a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M101 Howitzer
The M101A1 (previously designated M2A1) howitzer is an artillery piece developed and used by the United States. It was the standard U.S. light field howitzer in World War II and saw action in both the European and Pacific theaters and during the Korean War. Entering production in 1941, it quickly gained a reputation for accuracy and a powerful punch. The M101A1 fires 105 mm high explosive (HE) semi-fixed ammunition and has a range of , making it suitable for supporting infantry. All of these qualities of the weapon, along with its widespread production, led to its adoption by many countries after the war. Its ammunition type also became the standard for many foreign countries' later models. History Development and designation After World War I, the U.S. Army Ordnance Department studied various captured German 105 mm-caliber howitzers and developed the 105 mm Howitzer M1920 on Carriage M1920. A box trail carriage design (the M1925E carriage) and two other split trai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Castavinol C3
Castavinol C3 is a castavinol, a natural phenolic compound found in red wines.Castavinol, a new series of polyphenols from Bordeaux red wines. Chantal Castagnino and Joseph Vercauteren, Tetrahedron Letters, Volume 37, Issue 43, 21 October 1996, pp. 7739-7742, See also * phenolic compounds found in wine References External links 1996 : Les molécules des futurs millésimes Bordelais ? C. Castagnino, C. Chèze and J. Vercauteren, Bull. Soc. Pharm. Bordeaux, 1997, 136, pp. 19-36(French) Flavonoid glucosides {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.jpg "Click for more on -> Command, Control, And Communications")
