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C1-inhibitor
C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement system to prevent spontaneous activation but also as the major regulator of the contact system. C1-inhibitor is an acute-phase protein that circulates in blood at levels of around 0.25 g/ L. The levels rise ~2-fold during inflammation. C1-inhibitor irreversibly binds to and inactivates C1r and C1s proteases in the C1 complex of classical pathway of complement. MASP-1 and MASP-2 proteases in MBL complexes of the lectin pathway are also inactivated. This way, C1-inhibitor prevents the proteolytic cleavage of later complement components C4 and C2 by C1 and MBL. Although named after its complement inhibitory activity, C1-inhibitor also inhibits proteases of the fibrinolytic, clotting, and kinin pathways. Note that C1-inhibitor is the most important physiological inhibitor of plasma kallikrein, fXIa, and fXIIa. Proteomics ...
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C1 Field
C1, C01, C.I or C-1 may refer to: Arts and media * C1, a note-octave in music * C1 Television, a Mongolian television channel * Schecter C-1 Hellraiser FR, a guitar model * A Yamaha grand piano model * "C1", a slang expression in the video game ''Counter-Strike'', used to express agreement Biology and medicine Anatomy * Cervical vertebra 1, the first cervical vertebrae of the vertebral column * Cervical spinal nerve 1, a spinal nerve of the cervical segment Biochemistry * C1 complex, the first component of the classical complement pathway * C1 domain, an important secondary messenger protein domain * C1-inhibitor, a human serine protease inhibitor * C1 regulatory sequence for the insulin gene * Apolipoprotein C1, a human lipoprotein * Chlorophyll c1, a form of chlorophyll * Cytochrome C1, a precursor protein to Cytochrome C * Proanthocyanidin C1, a type of polyphenolic compound * Prostaglandin C1, a form of prostaglandins Other uses in biology and medicine * C1 and P1 ...
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C0 And C1 Control Codes
The C0 and C1 control code or control character sets define control codes for use in text by computer systems that use ASCII and derivatives of ASCII. The codes represent additional information about the text, such as the position of a cursor, an instruction to start a new line, or a message that the text has been received. C0 codes are the range 00 HEX–1FHEX and the default C0 set was originally defined in ISO 646 (ASCII). C1 codes are the range 80HEX–9FHEX and the default C1 set was originally defined in ECMA-48 (harmonized later with ISO 6429). The ISO/IEC 2022 system of specifying control and graphic characters allows other C0 and C1 sets to be available for specialized applications, but they are rarely used. C0 controls ASCII defined 32 control characters, plus a necessary extra character for the DEL character, 7FHEX or 01111111BIN (needed to punch out all the holes on a paper tape and erase it). This large number of codes was desirable at the time, as multi ...
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C1 And P1 (neuroscience)
The C1 and P1 (also called the P100) are two human scalp-recorded event-related brain potential (event-related potential (ERP)) components, collected by means of a technique called electroencephalography (EEG). The C1 is named so because it was the first component in a series of components found to respond to visual stimuli when it was first discovered. It can be a negative-going component (when using a mastoid reference point) or a positive going component with its peak normally observed in the 65–90 ms range post-stimulus onset. The P1 is called the P1 because it is the first positive-going component (when also using a mastoid reference point) and its peak is normally observed in around 100 ms. Both components are related to processing of visual stimuli and are under the category of potentials called visually evoked potentials (VEPs). Both components are theorized to be evoked within the visual cortices of the brain with C1 being linked to the primary visual cortex ...
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List Of Yamaha Products
This is a list of products made by Yamaha Corporation. This does not include products made by Bösendorfer, which has been a wholly owned subsidiary of Yamaha Corporation since February 1, 2008. For products made by Yamaha Motor Company, see the list of Yamaha motorcycles. Yamaha Motor Company shares the brand name but has been a separate company since 1955. Musical instruments Pianos In 1900, Yamaha started to manufacture pianos. Grand pianos ;CF series * FC / CF * CFIII * CFIIIS * CF4 (2010– * CF6 (2010– * CFX (2010–) ;C series * G1 / C1 / C1x ** DC1A * G2 / C2 /C2x ** G2F / DG2FII * C3 / C3x * #35 / G5 / ''new'' C5 / C5x * ''old'' C5 / C6 / C7 * G7 / C7 / C7x * SC / CS ;G series * ''G1, G2, G5, G7'' * #25 / G3 * GA1E / DGA1 GE] * GC1 ** GC1S / GC1SG ** GC1G / GC1FP ** GC1M / DGC1 / DGC1ME3 * GC2 * GH1 / GH1G * GT7 ;A series * A1 ** A1 S] G** DA1IIXG / DA1E3 / DA1M4 * EA1 ;S series * S4 ** S4BB ** DS4E3PRO PE * S6 ** S6BB ** DS6E3 ...
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C1 Complex
The C1 complex (''complement component 1'', ''C1'') is a protein complex involved in the complement system. It is the first component of the classical complement pathway and is composed of the subcomponents C1q, C1r and C1s. Structure The C1 complex is composed of 1 molecule of C1q, 2 molecules of C1r and 2 molecules of C1s, or ''C1qr2s2''. Function Activation of the C1 complex initiates the classical complement pathway. This occurs when C1q binds to antigen-antibody complexes. The antibodies IgM or certain subclasses of IgG complexed with antigens are able to initiate the complement system: a single pentameric IgM can initiate the pathway, while several monomeric IgG molecules are needed. C1q can also be activated in other ways, for example by binding to pentraxins such as C-reactive protein or directly to the surface of pathogens. Such binding of C1q leads to conformational changes in the C1q molecule, which activates the associated C1r molecules. Active C1r cleaves the ...
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C1 NES TV
The Nintendo Entertainment System (NES), an 8-bit third-generation home video game console produced by Nintendo, had numerous model variants produced throughout its lifetime. It was originally released in 1983 as the (and widely known as the ) in Japan, with design work led by Masayuki Uemura. Nintendo intentionally redesigned it as the NES in North America in an attempt to avoid the stigma of video game consoles lingering from the video game crash the same year; while it was initially conceptualized as a home computer, it was ultimately modeled after a videocassette recorder (VCR) for its debut there in 1985. Nintendo subsequently exported the NES to Europe and Oceania via local distributors. Uemura's former employer Sharp Corporation, which previously collaborated with Nintendo on the Game & Watch, released three officially licensed Famicom variants in Japan: a CRT television with a built-in Famicom, a console that combined the Famicom and Famicom Disk System hardware in one ...
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Proanthocyanidin C1
Procyanidin C1 (PCC1) is a B type proanthocyanidin. It is an epicatechin trimer found in grape (''Vitis vinifera''), unripe apples, and cinnamon. Natural occurrence and function Procyanidin C1 can be isolated from grape seed extract. Chemical synthesis The stereoselective synthesis of seven benzylated proanthocyanidin trimers (epicatechin-(4β-8)-epicatechin-(4β-8)-epicatechin trimer (procyanidin C1), catechin-(4α-8)-catechin-(4α-8)-catechin trimer ( procyanidin C2), epicatechin-(4β-8)-epicatechin-(4β-8)-catechin trimer and epicatechin-(4β-8)-catechin-(4α-8)-epicatechin trimer derivatives) can be achieved with TMSOTf-catalyzed condensation reaction, in excellent yields. The structure of benzylated procyanidin C2 was confirmed by comparing the 1H NMR spectra of protected procyanidin C2 that was synthesized by two different condensation approaches. Finally, deprotection of (+)-catechin and (-)-epicatechin trimers derivatives gives four natural procyanidin trimers in good ...
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Cytochrome C1
Cytochrome C1 (also known as Complex III subunit 4) is a protein encoded by the ''CYC1'' gene. Cytochrome is a heme-containing subunit of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. It is formed in the cytosol and targeted to the mitochondrial intermembrane space. Cytochrome c1 belongs to the cytochrome c family of proteins. Function Cytochrome C1 plays a role in the electron transfer during oxidative phosphorylation. As an iron-sulfur protein approaches the b-c1 complex, it accepts an electron from the cytochrome b subunit, then undergoes a conformational change to attach to cytochrome c1. There, the electron carried by the iron-sulfur protein is transferred to the heme carried by cytochrome c1. This electron is then transferred to a heme carried by cytochrome c. This creates a reduced species of cytochrome c, which separates from the b-c1 complex and moves to the ...
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C1 (protocol)
Punter is a protocol for file transfer developed in the 1980s by Steve Punter. There are various types of Punter such as PET Transfer Protocol (''PTP''), ''C1'' and ''C2''. PET Transfer Protocol The PET Transfer Protocol (''PTP''), also known as ''Punter'' or ''Old Punter'', was developed by Steve Punter for use with his PETBBS and BBS64 bulletin board system (BBS) software. The "PET" in the name comes from the Commodore PET computer. Compared to other contemporary protocols, ''PTP'' is slower than YMODEM and ZMODEM but faster and more reliable than XMODEM. The earliest version of Punter supports only 7-bit transfers and uses a back-correction algorithm involving two checksums for failsafes. One of the two checksums is additive, and the other is Boolean in nature (executing EOR instructions), making for an easy to understand algorithm for other programmers to understand and emulate. Having two checksums both of them being 16 bits wide makes it significantly more accurate t ...
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C1 Domain
C1 domain (also known as phorbol esters/diacylglycerol binding domain) binds an important secondary messenger diacylglycerol (DAG), as well as the analogous phorbol esters. Phorbol esters can directly stimulate protein kinase C, PKC. Phorbol esters (such as PMA) are analogues of DAG and potent tumor promoters that cause a variety of physiological changes when administered to both cells and tissues. DAG activates a family of serine/threonine protein kinases, collectively known as protein kinase C (PKC). Phorbol esters can directly stimulate PKC. The N-terminal region of PKC, known as C1, binds PMA and DAG in a phospholipid and zinc-dependent fashion. The C1 region contains one or two copies of a cysteine-rich domain, which is about 50 amino-acid residues long, and which is essential for DAG/PMA-binding. The DAG/PMA-binding domain binds two zinc ions; the ligands of these metal ions are probably the six cysteines and two histidines that are conserved in this domain. Human protein ...
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C1 Television
C1 Television ( mn, С1 Телевиз), or C1, is a television broadcaster in Mongolia. History Channel 1 television was founded on 24 April 2006. According to the station, it is the first in Mongolia to use fully digital video processing. TV programming C1 Television broadcasts a variety of programming. The following are noteworthy: * News. C1 gets its foreign news clips from Reuters, and its domestic news from its own crew. * Sport. C1 gets its sport news from the ESPN and Eurosport. C1 was the only official Mongolian broadcaster of 2010 FIFA World Cup in South Africa and aired all the matches live. The broadcasting was sponsored by several prominent local corporations that include Khan bank and Skytel among others. *Entertainment. C1 broadcasts Mongolian Movies, Talk shows, and Movie News. Also C1 broadcasts Bizarre Foods with Andrew Zimmern, Ben 10, and Skins (TV series). See also * Media of Mongolia *Communications in Mongolia Telecommunications in Mongolia face uniq ...
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