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Nikhil Dhurandhar
Nikhil V. Dhurandhar is a university professor who has published details about the proposed adipogenic effect of the human adenovirus AD-36 on laboratory animals and also its association with human obesity. He trained as a homeopath in India, studied Nutrition at North Dakota State University and has a PhD from Bombay. He has coined the term infectobesity. In his research, Dhurandhar also found animals infected with Ad-36 experienced a decrease in cholesterol, triglycerides and blood sugar despite causing weight gain. His research includes isolating the protein in the virus that leads to lower metabolic numbers to create a treatment for diabetes. Dhurandhar was the 2014-2015 president of the Obesity Society. He received the 2015 Osborne and Mendel Award, given by the American Society for Nutrition and recognizing recent outstanding basic research accomplishments in nutrition. Dhurandhar is chair of the Department of Nutritional Sciences at Texas Tech University. Before coming t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenovirus
Adenoviruses (members of the family ''Adenoviridae'') are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. Virology Classification This family contains the following genera: * '' Atadenovirus'' * '' Aviadenovirus'' * '' Ichtadenovirus'' * '' Mastadenovirus'' (including all human adenoviruses) * '' Siadenovirus'' * '' Testadenovirus'' Diversity In humans, currently there are 88 human adenoviruses (HAdVs) in seven species (Human adenovirus A to G): * A: 12, 18, 31 * B: 3, 7, 11, 14, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AD-36
Human adenovirus 36 (HAdV-36) or Ad-36 or Adv36 is one of 52 types of adenoviruses known to infect humans. AD-36, first isolated in 1978 from the feces of a girl suffering from diabetes and enteritis, has long been recognized as a cause of respiratory and eye infections in humans. It was first shown to be associated with obesity in chickens by Dr. Nikhil Dhurandhar. AD-36 infection can induce cellular differentiation of 3T3-L1 preadipocytes and stem cells derived from human adipose tissue. Role in obesity There has been a positive correlation between body fat and the presence of AD-36 antibodies in the blood. Previous research showed that chickens or mice injected with similar types of viruses show a statistically significant weight gain. To date, AD-36 is the only human adenovirus that has been linked with human obesity, present in 30% of obese humans and 11% of nonobese humans. In addition, a study of obese Americans indicates that about 30% of the obese individuals and onl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obesity
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are diet, physical activity, automation, urbanization, genetic susceptibility, medications, mental disorders, economic policies, endocrine disorders, and exposure to endocrine-disrupting chemicals. While a majority of obese individuals at any given time are attempting to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Int J Obes (Lond)
The ''International Journal of Obesity'' (abbreviated as ''IJO'') is a peer-reviewed medical journal published by the Nature Publishing Group. It was established in 1977 as ''International Journal of Obesity'' by Newman Pub. in collaboration with the Association for the Study of Obesity and the North American Association for the Study of Obesity. In 1992, the journal change its name to ''International Journal of Obesity and Related Metabolic Disorders'' upon acquisition by the Nature Publishing Group. In 2005, the journal returned to its original name. Aims and scope The journal addresses the development and treatment of obesity, and the functional impairments associated with the obese state. It publishes basic science and clinical studies that address the biochemical, epidemiological, genetical, molecular, metabolic, nutritional, physiological, psychological and sociological aspects of obesity.http://www2.nature.com/catalog/ijo International Journal of Obesity - Aims and Scop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infectobesity
The term "infectobesity" refers to the hypothesis that obesity in humans can be caused by pathogenic organisms, and the emerging field of medical research that studies the relationship between pathogens and weight gain. The term was coined in 2001 by Dr. Nikhil V. Dhurandhar, at the Pennington Biomedical Research Center. Bacteria The study of the effect of infectious agents on metabolism is still in its early stages. Gut flora has been shown to differ between lean and obese humans. There is an indication that gut flora in obese and lean individuals can affect the metabolic potential. This apparent alteration of the metabolic potential is believed to confer a greater capacity to harvest energy contributing to obesity. Whether these differences are the direct cause or the result of obesity has yet to be determined unequivocally. A possible mechanistic explanation linking gut flora to obesity involves short chain fatty acids. Humans are unable to digest complex polysaccharides and r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Texas Tech University
Texas Tech University (Texas Tech, Tech, or TTU) is a public research university in Lubbock, Texas. Established on , and called Texas Technological College until 1969, it is the main institution of the five-institution Texas Tech University System. The university's student enrollment is the sixth-largest in Texas as of the Fall 2020 semester. As of fall 2020, there were 40,322 students (33,269 undergraduate and 7,053 graduate) enrolled at Texas Tech. With over 25% of its undergraduate student population identifying as Hispanic, Texas Tech University is a designated Hispanic-serving institution (HSI). The university offers degrees in more than 150 courses of study through 13 colleges and hosts 60 research centers and institutes. Texas Tech University has awarded over 200,000 degrees since 1927, including over 40,000 graduate and professional degrees. Texas Tech is classified among "R1: Doctoral Universities – Very high research activity." Research projects in the areas o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pennington Biomedical Research Center
The Pennington Biomedical Research Center is a health science-focused research center in Baton Rouge, Louisiana. It is part of the Louisiana State University System and conducts clinical, basic, and population science research. It is the largest academically-based nutrition research center in the world, with the greatest number of obesity researchers on faculty. The center's over 500 employees occupy several buildings on the campus. The center was designed by the Baton Rouge architect John Desmond. History In 1980, Baton Rouge oilman and philanthropist C. B. "Doc" Pennington and his wife, Irene, provided $125 million to fund construction of the nutritional research center. With a U.S. Department of Defense contract and funding from the Louisiana Public Facilities Authority, Governor Buddy Roemer proclaimed the official opening of the Center in 1988. Dr George A. Bray, a renowned obesity researcher, was recruited to be the first executive director of the center and under his ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obesity Researchers
Obesity is a medical condition, sometimes considered a disease, in which excess Adipose tissue, body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is Obesity-associated morbidity, correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are diet, physical activity, automation, urbanization, quantitative trait locus, genetic susceptibility, medications, mental disorders, Economic policy, economic policies, Endocrine disease, endocrine disorders, and exposure to Endocr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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