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Neurochip
A neurochip is an integrated circuit chip (such as a microprocessor) that is designed for interaction with neuronal cells. Formation It is made of silicon that is doped in such a way that it contains EOSFETs (electrolyte- oxide-semiconductor field-effect transistors) that can sense the electrical activity of the neurons (action potentials) in the above-standing physiological electrolyte solution. It also contains capacitors for the electrical stimulation of the neurons. The University of Calgary, Faculty of Medicine scientists led by Pakistani-born Canadian scientist Naweed Syed who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip—or the brain on a microchip—have developed new technology that monitors brain cell activity at a resolution never achieved before. Developed with the National Research Council Canada (NRC), the new silicon chips are also simpler to use, which will help future understanding of how brain cells work un ...
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Brain–computer Interface
A brain–computer interface (BCI), sometimes called a brain–machine interface (BMI) or smartbrain, is a direct communication pathway between the brain's electrical activity and an external device, most commonly a computer or robotic limb. BCIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions. Implementations of BCIs range from non-invasive ( EEG, MEG, EOG, MRI) and partially invasive (ECoG and endovascular) to invasive (microelectrode array), based on how close electrodes get to brain tissue.Michael L Martini, BA, Eric Karl Oermann, MD, Nicholas L Opie, PhD, Fedor Panov, MD, Thomas Oxley, MD, PhD, Kurt Yaeger, MD, Sensor Modalities for Brain-Computer Interface Technology: A Comprehensive Literature Review, Neurosurgery, Volume 86, Issue 2, February 2020, Pages E108–E117/ref> Research on BCIs began in the 1970s by Jacques Vidal at the University of California, Los Angeles (UCLA) under a grant from ...
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Cultured Neuronal Networks
A cultured neuronal network is a cell culture of neurons that is used as a model to study the central nervous system, especially the brain. Often, cultured neuronal networks are connected to an input/output device such as a multi-electrode array (MEA), thus allowing two-way communication between the researcher and the network. This model has proved to be an invaluable tool to scientists studying the underlying principles behind neuronal learning, memory, plasticity, connectivity, and information processing. Cultured neurons are often connected via computer to a real or simulated robotic component, creating a hybrot or animat, respectively. Researchers can then thoroughly study learning and plasticity in a realistic context, where the neuronal networks are able to interact with their environment and receive at least some artificial sensory feedback. One example of this can be seen in the Multielectrode Array Art (MEART) system developed by the Potter Research Group at the Georgia ...
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Naweed Syed
Naweed I. Syed is a Pakistani-born Canadian neuro-scientist. He is the first scientist to connect brain cells to a silicon chip, creating the world's first neurochip. Syed has travelled worldwide giving lectures and presentations about the human mind and his mini-chip. Dr. Naweed Syed is a professor at the Cumming School of Medicine, University of Calgary. He also served for 10 years as the Department Head of anatomy and cell biology, Research Director HBI at the CSM and also the Postdoctoral Program Director – Office of the Vice President (Research) from 2012 – 2016. Syed has served and chaired almost all of the university's senior committees and was Special Advisor to Vice President Research for several years. Research Syed's research is focused at cellular and molecular mechanisms underlying brain development and plasticity. Specifically, he studies how networks of brain cells assemble during development and modified throughout life to form the basis for learning and me ...
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Action Potential
An action potential occurs when the membrane potential of a specific cell location rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and in some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell-cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward synaptic boutons situated at the ends of an axon; these signals can then connect with other neurons at synapses, or to motor cells or glands. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of event ...
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EOSFET
An EOSFET or electrolyte–oxide–semiconductor field-effect transistor is a FET, like a MOSFET, but with an electrolyte solution replacing the metal for the detection of neuronal activity. Many EOSFETs are integrated in a neurochip A neurochip is an integrated circuit chip (such as a microprocessor) that is designed for interaction with neuronal cells. Formation It is made of silicon that is doped in such a way that it contains EOSFETs (electrolyte- oxide-semiconductor .... Electrochemistry Sensors Transistor types MOSFETs Field-effect transistors {{electrochem-stub ...
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Brain Implant
Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain – usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g., in vision. Other brain implants are used in animal experiments simply to record brain activity for scientific reasons. Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain–computer interfaces. (Brain–computer interface research also includes technology such as EEG arrays that allow interface between mind and machine but do not require direct implantation of a device.) Neural implants such as deep brain st ...
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Integrated Circuit
An integrated circuit or monolithic integrated circuit (also referred to as an IC, a chip, or a microchip) is a set of electronic circuits on one small flat piece (or "chip") of semiconductor material, usually silicon. Large numbers of tiny MOSFETs (metal–oxide–semiconductor field-effect transistors) integrate into a small chip. This results in circuits that are orders of magnitude smaller, faster, and less expensive than those constructed of discrete electronic components. The IC's mass production capability, reliability, and building-block approach to integrated circuit design has ensured the rapid adoption of standardized ICs in place of designs using discrete transistors. ICs are now used in virtually all electronic equipment and have revolutionized the world of electronics. Computers, mobile phones and other home appliances are now inextricable parts of the structure of modern societies, made possible by the small size and low cost of ICs such as modern compute ...
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The Engineer (UK Magazine)
''The Engineer'' is a London-based monthly magazine and website covering the latest developments and business news in engineering and technology in the UK and internationally. History and description ''The Engineer'' was founded in January 1856. It was established by Edward Charles Healey, an entrepreneur and engineering enthusiast with financial interests in the railways whose friends included Robert Stephenson and Isambard Kingdom Brunel. The journal was created as a technical magazine for engineers. ''The Engineer'' began covering engineering including inventions and patents during a high point of British economic manufacturing power. In the 19th century it also published stock prices of raw materials. Together with the contemporary ''Engineering'' journal the work is considered a valuable historical resource for the study of British economic history. On 10 July 2012 the magazine announced its final print edition, the editor Jon Excell citing "increasing distribution and ...
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Integrated Circuits
An integrated circuit or monolithic integrated circuit (also referred to as an IC, a chip, or a microchip) is a set of electronic circuits on one small flat piece (or "chip") of semiconductor material, usually silicon. Large numbers of tiny MOSFETs (metal–oxide–semiconductor field-effect transistors) integrate into a small chip. This results in circuits that are orders of magnitude smaller, faster, and less expensive than those constructed of discrete electronic components. The IC's mass production capability, reliability, and building-block approach to integrated circuit design has ensured the rapid adoption of standardized ICs in place of designs using discrete transistors. ICs are now used in virtually all electronic equipment and have revolutionized the world of electronics. Computers, mobile phones and other home appliances are now inextricable parts of the structure of modern societies, made possible by the small size and low cost of ICs such as modern compu ...
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Neuroprosthetics
Neuroprosthetics (also called neural prosthetics) is a discipline related to neuroscience and biomedical engineering concerned with developing neural prostheses. They are sometimes contrasted with a brain–computer interface, which connects the brain to a computer rather than a device meant to replace missing biological functionality. Neural prostheses are a series of devices that can substitute a motor, sensory or cognitive modality that might have been damaged as a result of an injury or a disease. Cochlear implants provide an example of such devices. These devices substitute the functions performed by the eardrum and stapes while simulating the frequency analysis performed in the cochlea. A microphone on an external unit gathers the sound and processes it; the processed signal is then transferred to an implanted unit that stimulates the auditory nerve through a microelectrode array. Through the replacement or augmentation of damaged senses, these devices are intended to impr ...
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CoDi
CoDi is a cellular automaton (CA) model for spiking neural networks (SNNs). CoDi is an acronym for Collect and Distribute, referring to the signals and spikes in a neural network. CoDi uses a von Neumann neighborhood modified for a three-dimensional space; each cell looks at the states of its six orthogonal neighbors and its own state. In a growth phase a neural network is grown in the CA-space based on an underlying chromosome. There are four types of cells: neuron body, axon, dendrite and blank. The growth phase is followed by a signaling- or processing-phase. Signals are distributed from the neuron bodies via their axon tree and collected from connection dendrites. These two basic interactions cover every case, and they can be expressed simply, using a small number of rules. Cell interaction during signaling The neuron body cells collect neural signals from the surrounding dendritic cells and apply an internally defined function to the collected data. In the CoDi mo ...
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