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NeuroML
NeuroML is an XML (Extensible Markup Language) based model description language that aims to provide a common data format for defining and exchanging models in computational neuroscience. The focus of NeuroML is on models which are based on the biophysical and anatomical properties of real neurons. History The idea of creating NeuroML as a language for describing neuroscience models was first introduced by Goddard et al. (2001) following meetings in Edinburgh where initial templates for the language structures were discussed. This initial proposal was based on general purpose structures proposed by Gardner et al. (2001). At that time, the concept of NeuroML was closely linked with the idea of developing a software architecture in which a base application loads a range of plug-in components to handle different aspects of a simulation problem. Neosim (2003) was developed based on this goal, and early NeuroML development was closely aligned to this approach. Along with creating Neo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angus Silver
Robin Angus Silver is Professor of Neuroscience and a Wellcome Trust Principal Research Fellow at University College London. His laboratory studies neurotransmission and artificial neural networks by combining ''in vitro'' and ''in vivo'' experimental approaches with quantitative analysis and computational models developed ''in silico''. Education Silver was educated at Coventry Polytechnic where he graduated in 1986 with a Bachelor of Science degree in Physical Sciences. He completed postgraduate study at University College London where he was awarded a PhD in Neuroscience in 1990 for research investigating calcium signalling and second messenger systems in neural growth cones. Research and career Silver's work has contributed to our understanding of synaptic and neuronal function and to information processing in the brain. By developing and applying methods for quantifying synaptic properties his work has shown how central synapses transmit and transform signals and can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Common Data Model
A common data model (CDM) can refer to any standardised data model which allows for data and information exchange between different applications and data sources. Common data models aim to standardise logical infrastructure so that related applications can "operate on and share the same data", and can be seen as a way to "organize data from many sources that are in different formats into a standard structure". A common data model has been described as one of the components of a " strong information system". A standardised common data model has also been described as a typical component of a well designed agile application besides a common communication protocol. Providing a single common data model within an organisation is one of the typical tasks of a data warehouse. Examples of common data models Border crossings X-trans.eu was a cross-border pilot project between the Free State of Bavaria (Germany) and Upper Austria with the aim of developing a faster procedure for the ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Neuroscience
Computational neuroscience (also known as theoretical neuroscience or mathematical neuroscience) is a branch of neuroscience which employs mathematical models, computer simulations, theoretical analysis and abstractions of the brain to understand the principles that govern the development, structure, physiology and cognitive abilities of the nervous system. Computational neuroscience employs computational simulations to validate and solve mathematical models, and so can be seen as a sub-field of theoretical neuroscience; however, the two fields are often synonymous. The term mathematical neuroscience is also used sometimes, to stress the quantitative nature of the field. Computational neuroscience focuses on the description of biologically plausible neurons (and neural systems) and their physiology and dynamics, and it is therefore not directly concerned with biologically unrealistic models used in connectionism, control theory, cybernetics, quantitative psychology, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PLOS Computational Biology
''PLOS Computational Biology'' is a monthly peer-reviewed open access scientific journal covering computational biology. It was established in 2005 by the Public Library of Science in association with the International Society for Computational Biology (ISCB) in the same format as the previously established ''PLOS Biology'' and ''PLOS Medicine''. The founding editor-in-chief was Philip Bourne and the current ones are Feilim Mac Gabhann and Jason Papin. Format The journal publishes both original research and review articles. All articles are open access and licensed under the Creative Commons Attribution License. Since its inception, the journal has published the ''Ten Simple Rules'' series of practical guides, which has subsequently become one of the journals most read article series. The ''Ten Simple Rules'' series then led to the ''Quick Tips'' collection, whose articles contain recommendations on computational practices and methods, such as dimensionality reduction for exam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SBML
The Systems Biology Markup Language (SBML) is a representation format, based on XML, for communicating and storing computational models of biological processes. It is a free and open standard with widespread software support and a community of users and developers. SBML can represent many different classes of biological phenomena, including metabolic networks, cell signaling pathways, regulatory networks, infectious diseases, and many others. It has been proposed as a standard for representing computational models in systems biology today. History Late in the year 1999 through early 2000, with funding from the Japan Science and Technology Corporation (JST), Hiroaki Kitano and John C. Doyle assembled a small team of researchers to work on developing better software infrastructure for computational modeling in systems biology. Hamid Bolouri was the leader of the development team, which consisted of Andrew Finney, Herbert Sauro, and Michael Hucka. Bolouri identified the need for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuron (journal)
''Neuron'' is a biweekly peer-reviewed scientific journal published by Cell Press, and imprint of Elsevier. It was established in 1988, and covers neuroscience and related biological processes. The current editor in chief is Mariela Zirlinger. The founding editors were Lily Jan, A. James Hudspeth, Louis Reichardt Louis French Reichardt (born June 4, 1942) is a noted American neuroscientist and mountaineering, mountaineer, the first American to summit both Everest and K2. He was also director of the Simons Foundation Autism Research Initiative, the largest ..., Roger Nicoll, and Zach Hall. A past Editor in Chief was Katja Brose. Transcript and video available. Click on "Transcript" for text. * See alsoA Career in Science Editing: Katja BroseEditor in Chief, Neuron References External links * Neuroscience journals Cell Press academic journals Publications established in 1988 English-language journals Biweekly journals {{neuroscience-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metadata
Metadata is "data that provides information about other data", but not the content of the data, such as the text of a message or the image itself. There are many distinct types of metadata, including: * Descriptive metadata – the descriptive information about a resource. It is used for discovery and identification. It includes elements such as title, abstract, author, and keywords. * Structural metadata – metadata about containers of data and indicates how compound objects are put together, for example, how pages are ordered to form chapters. It describes the types, versions, relationships, and other characteristics of digital materials. * Administrative metadata – the information to help manage a resource, like resource type, permissions, and when and how it was created. * Reference metadata – the information about the contents and quality of statistical data. * Statistical metadata – also called process data, may describe processes that collect, process, or produce st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
OpenXDF
The Open eXchange Data Format, or OpenXDF, is an open, XML-based standard for the digital storage and exchange of time-series physiological signals and metadata. OpenXDF primarily focuses on electroencephalography and polysomnography. History Neurotronics began work on OpenXDF in 2003 with the goal of providing a modern, open, and extensible file format with which clinicians and researchers can share physiological data and metadata, such as signal data, signal montages, patient demographics, and event logs. Neurotronics released the first draft of the OpenXDF Specification just before the 18th meeting of the Associated Professional Sleep Societies in 2004. Neurotronics has since relinquished control of the format to the OpenXDF Consortium. As of version 1.0, OpenXDF is 100% backward compatible with the European Data Format (EDF), the current de facto standard format for physiological data exchange. Features Tiered structure OpenXDF is a tiered framework designed to allo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
