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Necrotizing Periodontal Diseases
Necrotizing periodontal diseases is one of the seven categories of periodontitis as defined by the American Academy of Periodontology 1999 classification system and is one of the three classifications of periodontal diseases and conditions within the 2017 classification. Necrotizing periodontal diseases are a type of inflammatory periodontal (gum) disease caused by bacteria (notably fusobacteria and spirochaete species). The diseases appear to represent different severities or stages of the same disease process, although this is not completely certain. These diseases usually have a sudden onset, and so the term acute is often added to the diagnosis. The mildest on the spectrum is necrotizing ulcerative gingivitis (NUG), followed by the successively more severe conditions necrotizing ulcerative periodontitis (NUP), necrotizing stomatitis and finally cancrum oris (noma), which is frequently fatal. Necrotizing ulcerative gingivitis Necrotizing ulcerative gingivitis, (NUG), or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Periodontitis
Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the tissues surrounding the teeth. In its early stage, called gingivitis, the gums become swollen and red and may bleed. It is considered the main cause of tooth loss for adults worldwide.V. Baelum and R. Lopez, “Periodontal epidemiology: towards social science or molecular biology?,”Community Dentistry and Oral Epidemiology, vol. 32, no. 4, pp. 239–249, 2004.Nicchio I, Cirelli T, Nepomuceno R, et al. Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects' Periodontal, Glycemic, and Lipid Profiles Journal of Diabetes Research. 2021 Jan;2021. PMCID: PMC8601849. In its more serious form, called periodontitis, the gums can pull away from the tooth, bone can be lost, and the teeth may loosen or fall out. Bad breath may also occur. Periodontal disease is generally due to bacteria in the mouth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Debridement
Debridement is the medical removal of dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue. Removal may be surgical, mechanical, chemical, autolytic (self-digestion), and by maggot therapy. In podiatry, practitioners such as chiropodists, podiatrists and foot health practitioners remove conditions such as calluses and verrucas. Debridement is an important part of the healing process for burns and other serious wounds; it is also used for treating some kinds of snake and spider bites. Sometimes the boundaries of the problem tissue may not be clearly defined. For example, when excising a tumor, there may be micrometastases along the edges of the tumor that are too small to be detected, but if not removed, could cause a relapse. In such circumstances, a surgeon may opt to debride a portion of the surrounding healthy tissue to ensure that the tumor is completely removed. Types There is lack of high quality evidence to compare th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gingivitis
Gingivitis is a non-destructive disease that causes inflammation of the gums. The most common form of gingivitis, and the most common form of periodontal disease overall, is in response to bacterial biofilms (also called plaque) that is attached to tooth surfaces, termed ''plaque-induced gingivitis''. Most forms of gingivitis are plaque-induced. While some cases of gingivitis never progress to periodontitis, periodontitis is always preceded by gingivitis. Gingivitis is reversible with good oral hygiene; however, without treatment, gingivitis can progress to periodontitis, in which the inflammation of the gums results in tissue destruction and bone resorption around the teeth. Periodontitis can ultimately lead to tooth loss. Signs and symptoms The symptoms of gingivitis are somewhat non-specific and manifest in the gum tissue as the classic signs of inflammation: *Swollen gums *Bright red gums *Gums that are tender or painful to the touch *Bleeding gums or bleeding after bru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pasteur Institute
The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. The institute was founded on 4 June 1887, and inaugurated on 14 November 1888. For over a century, the Institut Pasteur has researched infectious diseases. This worldwide biomedical research organization based in Paris was the first to isolate HIV, the virus that causes AIDS, in 1983. Over the years, it has been responsible for discoveries that have enabled medical science to control diseases such as diphtheria, tetanus, tuberculosis, poliomyelitis, influenza, yellow fever, and plague. Since 1908, ten Institut Pasteur scientists have been awarded the Nobel Prize for medicine and physiology—the 2008 Nobel Prize in Physiology or Medicine was shared between two Pasteur scientists. History The Institut Pasteur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean Hyacinthe Vincent
Jean Hyacinthe Henri Vincent (22 December 1862 – 23 November 1950) was a French physician who was a native of Bordeaux. He was an associate professor at Val-de-Grâce, as well as medical inspector general with the French Army. Later he attained the chair of epidemiology at Collège de France. Vincent is credited with the discovery of the organisms that cause an acute infection of the oral soft tissues, including the tonsils and pharynx. This condition is caused by the combination of the fusiform bacilli (''Bacillus fusiformis''), and the spirochete ('' Borrelia vincentii''). The disease was called Vincent's angina in honor of his discovery. Many publications using the term "Vincent's angina" date from the twentieth century, and the term is not so common in modern times. When the gums are involved, it was termed "Vincent's gingivitis". In modern times, Vincent's gingivitis is usually termed necrotizing ulcerative gingivitis (sometimes known as trench mouth). He is also rem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharyngitis
Pharyngitis is inflammation of the back of the throat, known as the pharynx. It typically results in a sore throat and fever. Other symptoms may include a runny nose, cough, headache, difficulty swallowing, swollen lymph nodes, and a hoarse voice. Symptoms usually last 3–5 days, but can be longer depending on cause. Complications can include sinusitis and acute otitis media. Pharyngitis is a type of upper respiratory tract infection. Most cases are caused by a viral infection. Strep throat, a bacterial infection, is the cause in about 25% of children and 10% of adults. Uncommon causes include other bacteria such as ''gonococcus'', fungi, irritants such as smoke, allergies, and gastroesophageal reflux disease. Specific testing is not recommended in people who have clear symptoms of a viral infection, such as a cold. Otherwise, a rapid antigen detection test or throat swab is recommended. PCR testing is becoming commonly used as it is as good as taking a throat swab but gives a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tonsillitis
Tonsillitis is inflammation of the tonsils in the upper part of the throat. It can be acute or chronic. Acute tonsillitis typically has a rapid onset. Symptoms may include sore throat, fever, enlargement of the tonsils, trouble swallowing, and enlarged lymph nodes around the neck. Complications include peritonsillar abscess. Tonsillitis is most commonly caused by a viral infection and about 5% to 40% of cases are caused by a bacterial infection.Lang 2009p. 2083./ref> When caused by the bacterium group A streptococcus, it is classed as streptococcal tonsillitis also referred to as ''strep throat''. Rarely bacteria such as '' Neisseria gonorrhoeae'', '' Corynebacterium diphtheriae'', or ''Haemophilus influenzae'' may be the cause. Typically the infection is spread between people through the air. A scoring system, such as the Centor score, may help separate possible causes. Confirmation may be by a throat swab or rapid strep test. Treatment efforts involve improving symptoms and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Noma
Noma, NoMa, or NOMA may refer to: Places * NoMa, the area North of Massachusetts Avenue in Washington, D.C., US ** NoMa–Gallaudet U station, on Washington Metro * Noma, Florida, US * NOMA, Manchester, a redevelopment in England * Noma District, Ehime, a former district in Iyo Province, Japan * Noma Station, Mihama, Aichi, Japan People Given name *Noma, a diminutive of the Russian name Avtonom *Noma Bar (born 1973), Israeli-British artist *Noma Dumezweni (born 1969), Swazi-British actress * Noma Gurich (born 1952), American judge Surname *Akiko Noma (born 1980), Japanese musician * Akinori Noma, Japanese electrophysiologist * Hiroshi Noma (1915–1991), Japanese author *Seiji Noma (1878–1938), Japanese writer and publisher Arts, entertainment, and media *Noma Prizes, Japanese literary awards ** Noma Award for Publishing in Africa Biology *''Archipsocus nomas'', a barklouse of the family Archipsocidae *''Euxoa nomas'', a moth of the family Noctuidae * Noma pony, a Japane ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mucogingival Junction
A mucogingival junction is an anatomical feature found on the intraoral mucosa. The mucosa of the cheeks and floor of the mouth are freely moveable and fragile, whereas the mucosa around the teeth and on the palate are firm and keratinized. Where the two tissue types meet is known as a mucogingival junction. There are three mucogingival junctions: on the facial of the maxilla and on both the facial and lingual of the mandible. The palatal gingiva of the maxilla is continuous with the tissue of the palate, which is bound down to the palatal bones. Because the palate is devoid of freely moveable alveolar mucosa, there is no mucogingival junction.Carranza's Clinical Periodontology, W.B. Saunders 2002, page 17. Clinical importance The clinical importance of the mucogingival junction is in measuring the width of attached gingiva. Attached gingiva is important because it is bound very tightly to the underlying alveolar bone and provides protection to the mucosa during functional u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Periodontal Ligament
The periodontal ligament, commonly abbreviated as the PDL, is a group of specialized connective tissue fibers that essentially attach a tooth to the alveolar bone within which it sits. It inserts into root cementum one side and onto alveolar bone on the other. Structure The PDL consists of principal fibres, loose connective tissue, blast and clast cells, oxytalan fibres and Cell Rest of Malassez. Alveolodental ligament The main principal fiber group is the alveolodental ligament, which consists of five fiber subgroups: alveolar crest, horizontal, oblique, apical, and interradicular on multirooted teeth. Principal fibers other than the alveolodental ligament are the transseptal fibers. All these fibers help the tooth withstand the naturally substantial compressive forces that occur during chewing and remain embedded in the bone. The ends of the principal fibers that are within either cementum or alveolar bone proper are considered Sharpey fibers. * Alveolar crest fibers ('' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gingiva
The gums or gingiva (plural: ''gingivae'') consist of the mucosal tissue that lies over the mandible and maxilla inside the mouth. Gum health and disease can have an effect on general health. Structure The gums are part of the soft tissue lining of the mouth. They surround the teeth and provide a seal around them. Unlike the soft tissue linings of the lips and cheeks, most of the gums are tightly bound to the underlying bone which helps resist the friction of food passing over them. Thus when healthy, it presents an effective barrier to the barrage of periodontal insults to deeper tissue. Healthy gums are usually coral pink in light skinned people, and may be naturally darker with melanin pigmentation. Changes in color, particularly increased redness, together with swelling and an increased tendency to bleed, suggest an inflammation that is possibly due to the accumulation of bacterial plaque. Overall, the clinical appearance of the tissue reflects the underlying histology, b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metronidazole
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. It is an option for a first episode of mild-to-moderate ''Clostridium difficile'' colitis if vancomycin or fidaxomicin is unavailable. Metronidazole is available by mouth, as a cream, and by injection into a vein. Common side effects include nausea, a metallic taste, loss of appetite, and headaches. Occasionally seizures or allergies to the medication may occur. Some state that metronidazole should not be used in early pregnancy, while others state doses for trichomoniasis are safe. Metronidazole is generally considered compatible with breastfeeding. Metronidazole began to be commercially used in 1960 in France. It is on the World Health Organization's List of Esse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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