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Napp Pharmaceuticals
Napp Pharmaceuticals Limited is a private pharmaceutical company in Cambridge, United Kingdom that was founded in 1923 and bought by the Sackler family in 1966. Headquartered together with the related Napp Research Centre in the Cambridge Science Park since the 1980's, it is a sister company of Purdue Pharma and Mundipharma, all of which are owned by the descendants of Mortimer and Raymond Sackler. Products The company produces an array of pharmaceutical products, many for pain management, among them branded forms of oxycodone that have been identified as key drugs in the opioid epidemic. In the early 1970s, scientists at Napp developed a delivery system whereby a pill would slowly absorbed by the body, thereby continuously delivering a drug over a 12 hour period. This Continus® delivery system was used by Purdue first to introduce MS Continus in 1987 and Oxycontin eight years later. 1995 chemical plant explosion At 7:50 AM on April 22, 1995, the chemical plant run by N ...
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MST Continus Branded Morphine 10mg (NAPP Side)
The Master of Studies or Master in Studies (M.St. or MSt; ) is a postgraduate degree at the University of Oxford, University of Cambridge, University of St Andrews, the Australian National University, University of Dublin and the University of Newcastle (Australia). Depending on the degree, it is comparable to the Master of Arts, Master of Business Administration, Master of Laws, Master of Philosophy, and Master of Science. Its creation was necessitated, in part, by the fact that the Master of Arts degree at Oxford, Cambridge, and Dublin is automatically awarded to graduates after a certain period of time. In contrast, the Master of Studies requires completion of classroom study and a thesis. See also * British degree abbreviations * Master's degree in Europe * Master of Studies in Law * Master of Philosophy The Master of Philosophy (MPhil; Latin ' or ') is a postgraduate degree. In the United States, an MPhil typically includes a taught portion and a significant research port ...
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Oxycodone
Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a strong, semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive and a commonly drug abuse, abused drug. It is usually taken oral administration, by mouth, and is available in immediate release, immediate-release and controlled release, controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination drug, Combination products are also available with oxycodone/paracetamol, paracetamol (acetaminophen), oxycodone/ibuprofen, ibuprofen, oxycodone/naloxone, naloxone, naltrexone, and oxycodone/aspirin, aspirin. Common side effects include euphoria, constipation, nausea, vomiting, Anorexia (symptom), loss of appetite, Somnolence, drowsiness, dizziness, itching, X ...
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1923 Establishments In England
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album ''Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipknot. ...
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Pharmaceutical Companies Of England
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapies). ...
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Aluminium Powder
Aluminium powder is powdered aluminium. This was originally produced by mechanical means using a stamp mill to create flakes. Subsequently, a process of spraying molten aluminium to create a powder of droplets was developed by E. J. Hall in the 1920s. The resulting powder might then be processed further in a ball mill to flatten it into flakes for use as a coating or pigment. Characteristics The melting point of aluminium powder is 660 °C. Usage * autoclave aerated concrete * cosmetic colourant * fingerprint powder * metallic paint * pyrotechnics (including the M-80 firecracker) * refractory * rocket and missile fuel such as the solid rocket boosters of the Space Shuttle * thermite Depending on the usage, the powder is either coated or uncoated. Safety Aluminium is insoluble. If the powder or dust is breathed in then little of it will be absorbed but it may interfere with the clearance mechanism of the lung. High levels of exposure over many years may result in alu ...
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Sodium Hydrosulfite
Sodium dithionite (also known as sodium hydrosulfite) is a white crystalline powder with a sulfurous odor. Although it is stable in dry air, it Chemical decomposition, decomposes in hot water and in acid Solution (chemistry), solutions. Structure The structure has been examined by Raman spectroscopy and single-crystal X-ray diffraction. The dithionite dianion has C symmetry group, symmetry, with almost eclipsed with a 16° O-S-S-O torsional angle. In the Hydrate, dihydrated form (), the dithionite anion has Alkane stereochemistry, gauche 56° O-S-S-O torsional angle. A weak S-S bond is indicated by the S-S distance of 239 pm, which is elongated by ca. 30 pm relative to a typical S-S bond. Because this bond is fragile, the dithionite anion dissociates in solution into the [SO2]− radicals, as has been confirmed by EPR spectroscopy. It is also observed that 35S undergoes rapid exchange between S2O42− and SO2 in neutral or acidic solution, consistent with the weak S-S bond in t ...
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OxyContin
Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a strong, semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive and a commonly abused drug. It is usually taken by mouth, and is available in immediate-release and controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin. Common side effects include euphoria, constipation, nausea, vomiting, loss of appetite, drowsiness, dizziness, itching, dry mouth, and sweating. Severe side effects may include addiction and dependence, substance abuse, irritability, depression or mania, delirium, hallucinations, hypoventilation, gastroparesis, bradycar ...
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Ms Contin
MS, ms, Ms, M.S., etc. may refer to: Arts and entertainment * ''Ms.'' (magazine), an American feminist magazine * Metal Storm (webzine), a heavy metal website based in Estonia Businesses and organizations * MS-13, criminal gang * Missionaries of La Salette, a Catholic male religious order * Młodzi Socjaliści (Young Socialists), a former Polish socialist youth organization * Morgan Stanley, a US investment bank (NYSE stock symbol: MS) * Mjólkursamsalan, an Icelandic dairy company Educational qualifications * Master of Science, a master's degree in the field of science * Master of Surgery, an advanced medical degree * Master Sommelier, a terminal degree in the field of wine * '' Mastère spécialisé'', a French postgraduate ''grande école'' master's degree Medicine * Mitral stenosis, narrowing of the mitral valve of the heart * Morphine sulfate, an opiate pain-relieving drug * Multiple sclerosis, a disease of the nervous system Military * Master seaman, a non-commissio ...
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Financial Times
The ''Financial Times'' (''FT'') is a British daily newspaper printed in broadsheet and published digitally that focuses on business and economic current affairs. Based in London, England, the paper is owned by a Japanese holding company, Nikkei, with core editorial offices across Britain, the United States and continental Europe. In July 2015, Pearson sold the publication to Nikkei for £844 million (US$1.32 billion) after owning it since 1957. In 2019, it reported one million paying subscriptions, three-quarters of which were digital subscriptions. The newspaper has a prominent focus on financial journalism and economic analysis over generalist reporting, drawing both criticism and acclaim. The daily sponsors an annual book award and publishes a " Person of the Year" feature. The paper was founded in January 1888 as the ''London Financial Guide'' before rebranding a month later as the ''Financial Times''. It was first circulated around metropolitan London by James Sherid ...
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ProPublica
ProPublica (), legally Pro Publica, Inc., is a nonprofit organization based in New York City. In 2010, it became the first online news source to win a Pulitzer Prize, for a piece written by one of its journalists''The Guardian'', April 13, 2010Pulitzer progress for non-profit newsProPublicaPulitzer Prize in Investigative Reporting: Deadly Choices at Memorial and published in ''The New York Times Magazine''Sheri Fink, '' New York Times Magazine'', August 25, 2009The Deadly Choices at Memorial as well as on ProPublica.org.ProPublica, August 27, 2009The Deadly Choices at Memorial ProPublica states that its investigations are conducted by its staff of full-time investigative reporters, and the resulting stories are distributed to news partners for publication or broadcast. In some cases, reporters from both ProPublica and its partners work together on a story. ProPublica has partnered with more than 90 different news organizations, and it has won six Pulitzer Prizes. History ProPub ...
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New England Journal Of Medicine
''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. History In September 1811, John Collins Warren, a Boston physician, along with James Jackson, submitted a formal prospectus to establish the ''New England Journal of Medicine and Surgery and Collateral Branches of Science'' as a medical and philosophical journal. Subsequently, the first issue of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' was published in January 1812. The journal was published quarterly. In 1823, another publication, the ''Boston Medical Intelligencer'', appeared under the editorship of Jerome V. C. Smith. The editors of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' purchased the weekly ''Intelligencer'' for $600 in 1 ...
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Opioid Epidemic
The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either in part or in whole to the class of drugs opiates/opioids since the 1990s. It includes the significant medical, social, psychological, and economic consequences of the medical, non-medical, and recreational abuse of these medications. Opioids are a diverse class of moderate to strong painkillers, including oxycodone (commonly sold under the trade names OxyContin and Percocet), hydrocodone (Vicodin, Norco), and fentanyl, which is a very strong painkiller that is synthesized to resemble other opiates such as opium-derived morphine and heroin. The potency and availability of these substances, despite the potential risk of addiction and overdose, have made them popular both as medical treatments and as recreational drugs. Due to the sedative effects of opioids on the respiratory center of the medulla oblongata, opioids in high doses ...
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