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Naphthomycin A
Naphthomycin A is a type of naphthomycin. It was isolated as a yellow pigment from '' Streptomyces collinus'' and it shows antibacterial, antifungal, and antitumor activities. Naphthomycins have the longest ansa aliphatic carbon chain of the ansamycin family. Biosynthetic origins of the carbon skeleton from PKS1 were investigated by feeding 13C-labeled precursors and subsequent 13C-NMR Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a ... product analysis. Naphthomycin gene clusters have been cloned and sequenced to confirm involvement in biosynthesis via deletion of a 7.2kb region. Thirty-two genes were identified in the 106kb cluster. References {{antibiotic-stub Pigments Antibiotics Ansamycins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Naphthomycin
Naphthomycins are a group of closely related antimicrobial chemical compounds isolated from ''Streptomyces''. They are considered a subclass of ansamycin Ansamycins is a family of bacterial secondary metabolites that show antimicrobial activity against many Gram-positive and some Gram-negative bacteria, and includes various compounds, including streptovaricins and rifamycins. In addition, these ...s. Members include: * Naphthomycin A * Naphthomycin B * Naphthomycin C * Naphthomycin D * Naphthomycin E * Naphthomycin F * Naphthomycin G * Naphthomycin H * Naphthomycin I * Naphthomycin J * Naphthomycin K * Naphthomycin L * Naphthomycin M * Naphthomycin N Chemical structures File:Naphthomycin A.svg, Naphthomycin A File:Naphthomycin B.svg, Naphthomycin B File:Naphthomycin C.svg, Naphthomycin C File:Naphthomycin D.svg, Naphthomycin D File:Naphthomycin E.svg, Naphthomycin E File:Naphthomycin F.svg, Naphthomycin F File:Naphthomycin G.svg, Naphthomycin G References {{reflist Ant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptomyces Collinus
''Streptomyces collinus'' is a bacterium species from the genus of ''Streptomyces'' which has been isolated from soil in Baden in Germany. Deutsche Sammlung von Mikroorganismen und Zellkulturenbr>/ref> ''Streptomyces collinus'' produces ansatrienin A2, ansatrienin A3, ansatrienin B, naphthomycin A, collinomycine, toromycin, streptocollin, kirromycin and rubromycine. Further reading * * * * * * * * * * See also * List of Streptomyces species A ''list'' is any set of items in a row. List or lists may also refer to: People * List (surname) Organizations * List College, an undergraduate division of the Jewish Theological Seminary of America * SC Germania List, German rugby union ... References External linksType strain of ''Streptomyces collinus'' at Bac''Dive'' - the Bacterial Diversity Metadatabase collinus Bacteria described in 1952 {{Streptomyces-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ansamycin
Ansamycins is a family of bacterial secondary metabolites that show antimicrobial activity against many Gram-positive and some Gram-negative bacteria, and includes various compounds, including streptovaricins and rifamycins. In addition, these compounds demonstrate antiviral activity towards bacteriophages and poxviruses. Structure They are named ansamycins (from the Latin ansa, ''handle'') because of their unique structure, which consists of an aromatic moiety bridged by an aliphatic chain. The main difference between various derivatives of ansamycins is the aromatic moiety, which can be a naphthalene ring or a naphthoquinone ring as in rifamycin and the naphthomycins. Another variation consists of benzene or a benzoquinone ring system as in geldanamycin or ansamitocin. Ansamycins were first discovered in 1959 by Sensi et al. from ''Amycolatopsis mediterranei'', an actinomycete bacterium. Examples Rifamycins are a subclass of ansamycins with high potency against mycobact ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyketide Synthase
Polyketides are a class of natural products derived from a precursor molecule consisting of a chain of alternating ketone (or reduced forms of a ketone) and methylene groups: (-CO-CH2-). First studied in the early 20th century, discovery, biosynthesis, and application of polyketides has evolved. It is a large and diverse group of secondary metabolites caused by its complex biosynthesis which resembles that of fatty acid synthesis. Because of this diversity, polyketides can have various medicinal, agricultural, and industrial applications. Many polyketides are medicinal or exhibit acute toxicity. Biotechnology has enabled discovery of more naturally-occurring polyketides and evolution of new polyketides with novel or improved bioactivity. History Naturally produced polyketides by various plants and organisms have been used by humans since before studies on them began in the 19th and 20th century. In 1893, J. Norman Collie synthesized detectable amounts of orcinol by heating dehy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuclear Magnetic Resonance
Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca. 20 tesla, the frequency is similar to VHF and UHF television broadcasts (60–1000 MHz). NMR results from specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics and crystals as well as non-crystalline materials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Naphthomycin A 2
Naphthomycins are a group of closely related antimicrobial chemical compounds isolated from ''Streptomyces''. They are considered a subclass of ansamycins. Members include: * Naphthomycin A Naphthomycin A is a type of naphthomycin. It was isolated as a yellow pigment from '' Streptomyces collinus'' and it shows antibacterial, antifungal, and antitumor activities. Naphthomycins have the longest ansa aliphatic carbon chain of the ansa ... * Naphthomycin B * Naphthomycin C * Naphthomycin D * Naphthomycin E * Naphthomycin F * Naphthomycin G * Naphthomycin H * Naphthomycin I * Naphthomycin J * Naphthomycin K * Naphthomycin L * Naphthomycin M * Naphthomycin N Chemical structures File:Naphthomycin A.svg, Naphthomycin A File:Naphthomycin B.svg, Naphthomycin B File:Naphthomycin C.svg, Naphthomycin C File:Naphthomycin D.svg, Naphthomycin D File:Naphthomycin E.svg, Naphthomycin E File:Naphthomycin F.svg, Naphthomycin F File:Naphthomycin G.svg, Naphthomycin G References {{reflist A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pigments
A pigment is a colored material that is completely or nearly insoluble in water. In contrast, dyes are typically soluble, at least at some stage in their use. Generally dyes are often organic compounds whereas pigments are often inorganic compounds. Pigments of prehistoric and historic value include ochre, charcoal, and lapis lazuli. Economic impact In 2006, around 7.4 million tons of inorganic, organic, and special pigments were marketed worldwide. Estimated at around US$14.86 billion in 2018 and will rise at over 4.9% CAGR from 2019 to 2026. The global demand for pigments was roughly US$20.5 billion in 2009. According to an April 2018 report by ''Bloomberg Businessweek'', the estimated value of the pigment industry globally is $30 billion. The value of titanium dioxide – used to enhance the white brightness of many products – was placed at $13.2 billion per year, while the color Ferrari red is valued at $300 million each year. Physical principles Lik ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antisep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
