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Nippostrongylus Brasiliensis
''Nippostrongylus brasiliensis'' is a gastrointestinal roundworm that infects rodents, primarily rats. This worm is a widely studied parasite due to its simple lifecycle and its ability to be used in animal models. Its lifecycle similar to the human hookworms ''Necator americanus'' and ''Ancylostoma duodenale'' which includes five molting stages to become sexually mature. Lifecycle Eggs located within the soil release motile, free-living worms that must moult twice (L1 and L2) to develop into their infective L3 stage. This L3 stage can penetrate through intact skin in as little as 4 hours. Once inside the host, the worms invade the venous circulation and are carried into the lungs, where they become trapped in the capillaries. When the worms mature into the L4 stage, they rupture the capillaries and are released into the alveoli, where they are coughed up and swallowed. They then reach the small intestines 3–4 days after the initial infection. The worms become adults after the ...
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Roundworm
The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a broad range of environments. Less formally, they are categorized as Helminths, but are taxonomically classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa, and unlike flatworms, have tubular digestive systems with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species described to date vary by author and may change rapidly over time. A 2013 survey of animal biodiversity published in the mega journal ...
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Necator Americanus
''Necator americanus'' is a species of hookworm (a type of helminth) commonly known as the New World hookworm. Like other hookworms, it is a member of the phylum Nematoda. It is an obligatory parasitic nematode that lives in the small intestine of human hosts. Necatoriasis—a type of helminthiasis—is the term for the condition of being host to an infestation of a species of ''Necator''. Since ''N. americanus'' and ''Ancylostoma duodenale'' (also known as Old World hookworm) are the two species of hookworms that most commonly infest humans, they are usually dealt with under the collective heading of "hookworm infection". They differ most obviously in geographical distribution, structure of mouthparts, and relative size. ''Necator americanus'' has been proposed as an alternative to ''Trichuris suis'' in helminthic therapy. Morphology This parasite has two dorsal and two ventral cutting plates around the anterior margin of the buccal capsule. It also has a pair of subdorsal ...
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Ancylostoma Duodenale
''Ancylostoma'' is a genus of nematodes that includes some species of hookworms. Species include: : '' Ancylostoma braziliense'', commonly infects cats, popularly known in Brazil as ''bicho-geográfico'' : '' Ancylostoma caninum'', commonly infects dogs : '' Ancylostoma ceylanicum'' : ''Ancylostoma duodenale'' : '' Ancylostoma pluridentatum'', commonly infects sylvatic cats : '' Ancylostoma tubaeforme'', infects cats along with other hosts See also * Ancylostomiasis * List of parasites (human) Endoparasites Protozoan organisms Helminths (worms) Helminth organisms (also called helminths or intestinal worms) include: Tapeworms Flukes Roundworms Other organisms Ectoparasites References {{Portal bar, Bio ... External links * Ancylostomatidae Rhabditida genera {{Rhabditida-stub ...
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Franca Ronchese
Franca Ronchese is an Italian-New Zealand immunologist. She currently leads the immune cell biology programme at the Malaghan Institute of Medical Research in Wellington, New Zealand and is a research professor at Victoria University of Wellington. Career After a PhD at the University of Padua, Italy, Ronchese worked as a postdoctoral fellow in the laboratory of Ronald Germain at the National Institutes of Health in the United States. After her postdoctoral studies, she joined the Basel Institute for Immunology, Switzerland, where she became interested in antigen presentation by dendritic cells in vivo. In 1994, Ronchese moved to New Zealand to establish her research programme at the Malaghan Institute of Medical Research, with a focus on developing immune therapies for cancer and allergies. Her current research focuses on dendritic cells (a kind of immune cell), and includes allergic response work. In 2012, Ronchese was a finalist in the NEXT Woman of the Year. In 2018, she w ...
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Tetramisole
Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. It is taken by mouth. Side effects may include abdominal pain, vomiting, headache, and dizziness. Use is not recommended during breastfeeding or the third trimester of pregnancy. Serious side effects may include an increased risk of infection. It belongs to the anthelmintic class of medications. Levamisole was discovered in 1966. It is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. It is not commercially available in the United States. Levamisole is also used as a dewormer for livestock. Medical uses Worms Levamisole was originally used as an anthelmintic to treat worm infestations in both humans and animals. Levamisole works as a nicotinic acetylcholine receptor agonist that causes continued stimulation of the parasitic worm muscles, leading to paralysis ...
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Zeolite
Zeolites are microporous, crystalline aluminosilicate materials commonly used as commercial adsorbents and catalysts. They mainly consist of silicon, aluminium, oxygen, and have the general formula ・y where is either a metal ion or H+. These positive ions can be exchanged for others in a contacting electrolyte solution. exchanged zeolites are particularly useful as solid acid catalysts. The term ''zeolite'' was originally coined in 1756 by Swedish mineralogist Axel Fredrik Cronstedt, who observed that rapidly heating a material, believed to have been stilbite, produced large amounts of steam from water that had been adsorbed by the material. Based on this, he called the material ''zeolite'', from the Greek , meaning "to boil" and , meaning "stone". Zeolites occur naturally but are also produced industrially on a large scale. , 253 unique zeolite frameworks have been identified, and over 40 naturally occurring zeolite frameworks are known. Every new zeolite structure that is ob ...
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Heligmosomoides Polygyrus
''Heligmosomoides polygyrus'', previously named ''Nematospiroides dubius'', is a naturally occurring intestinal roundworm of rodents. It belongs to the family Trychostrongylidae, and male and female worms are morphologically distinguishable. The parasite has a direct lifecycle, with its larval form being the infective stage. ''H. polygyrus'' has the ability to establish chronic infections in rodents and alter host immune responses. This nematode is widely used as a gastrointestinal parasitic model in immunological, pharmacological, and toxicological studies. Lifecycle and morphology This parasite has a direct lifecycle with no intermediate hosts. The lifecycle takes about 13–15 days to complete. Infected mice pass faeces containing eggs, and egg sizes vary between 70 and 84 micrometres (µm) in length and 37 and 53 µm in width. Eggs are shed from the host at the 8– to 16-cell stage and hatch in the environment, roughly 24 hours after passing through the host. L1 larv ...
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Trichuris Muris
''Trichuris muris'' is a nematode parasite of mice. It is very similar to the human roundworm parasite ''Trichuris trichiura'' due to its immunological reactivity when crossed, and so is often used in related studies. Lifecycle Ingesting material that contains embryonated eggs allows for transmission and infection to occur. The eggs travel down to the cecum - a pouch located at the start of the large intestine - where larval hatching is induced. The larvae proceed to penetrate through the mucosal epithelium, then molt into their secondary stage of infection after 9–11 days. About 17 days after infection, the larvae arrive at the tertiary stage followed by a quaternary molt 5 days later. The larvae complete their last molt 29 days after infection and transform into mature dioecious adults. These whipworms use their anterior ends to embed themselves into the cells that line the walls of the large intestine. After establishing their place in the intestinal wall, the adult worms ...
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Strongylida
The Strongylida suborder includes many of the important nematodes found in the gastrointestinal tracts of ruminants, horses, and swine, as well as the lungworms of ruminants and the hookworms of dogs and cats. Taxonomy This suborder includes (superfamily - included families): *Ancylostomatoidea ** Ancylostomatidae * Diaphanocephaloidea **Diaphanocephalidae * Heligmosomoidea ** Heligmosomidae * Metastrongyloidea **Angiostrongylidae **Crenosomatidae **Filaroididae **Metastrongylidae **Protostrongylidae **Pseudaliidae ** Syngamidae * Molineoidea ** Molineidae * Strongyloidea **Chabertiidae **Cloacinidae ** Deletrocephalidae ** Stephanuridae **Strongylidae *Trichostrongyloidea ** Amidostomatidae **Cooperiidae ** Dictyocaulidae ** Dromaeostrongylidae ** Haemonchidae ** Heligmonellidae **Heligmosomatidae ** Herpetostrongylidae ** Mackerrasrtongylidae ** Nicollinidae **Trichostrongylidae Major superfamilies Diaphanocephaloidea These are parasites of the digestive tracts of terrestr ...
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Parasitic Nematodes Of Mammals
Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophicallytransmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation. One major axis of classification concerns invasiveness: an endoparasite lives inside the host's body; an ect ...
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Parasites Of Rodents
Parasitism is a Symbiosis, close relationship between species, where one organism, the parasite, lives on or inside another organism, the Host (biology), host, causing it some harm, and is Adaptation, adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as Armillaria mellea, honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the Orobanchaceae, broomrapes. There are six major parasitic Behavioral ecology#Evolutionarily stable strategy, strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), wikt:trophic, trophicallytransmitted parasitism (by being eaten), Disease vector, vector-transmitted paras ...
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