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Nipah Virus Infection
A Nipah virus infection is a viral infection caused by the Nipah virus. Symptoms from infection vary from none to fever, cough, headache, shortness of breath, and confusion. This may worsen into a coma over a day or two, and 50 to 75% of those infected die. Complications can include inflammation of the brain and seizures following recovery. The Nipah virus (NiV) is a type of RNA virus in the genus ''Henipavirus''. The virus normally circulates among some fruit bats. It can both spread between people and from other animals to people. Spread typically requires direct contact with an infected source. Diagnosis is based on symptoms and confirmed by laboratory testing. Management is restricted to supportive care; there is neither vaccine nor specific treatment. Preventive measures include avoiding exposure to bats and sick pigs, and not drinking raw date palm sap. As of May 2018 about 700 human cases of Nipah virus were estimated to have occurred, and 50 to 75 percent of those ...
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Palm Toddy
Palm wine, known by several #Names, local names, is an alcoholic beverage created from the sap of various species of palm tree such as the Borassus, palmyra, date palms, and coconut palms. It is known by various names in different regions and is common in various parts of Africa, the Caribbean, South America, South Asia, Southeast Asia and Micronesia. Palm wine production by smallholders and individual farmers may promote conservation as palm trees become a source of regular household income that may economically be worth more than the value of timber sold. Tapping The sap is extracted and collected by a tapper. Typically the sap is collected from the cut flower of the palm tree. A container is fastened to the flower stump to collect the sap. The white liquid that initially collects tends to be very sweet and non-Alcoholic beverage, alcoholic before it is fermentation (food), fermented. An alternative method is the felling of the entire tree. Where this is practised, a fi ...
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Henipavirus
''Henipavirus'' is a genus of negative-strand RNA viruses in the family ''Paramyxoviridae'', order ''Mononegavirales'' containing six established species, and numerous others still under study. Henipaviruses are naturally harboured by several species of small mammals, notably Pteropus, pteropid fruit bats (flying foxes), microbats of several species, and shrews. Henipaviruses are characterised by long genomes and a wide host range. Their recent emergence as zoonosis, zoonotic pathogens capable of causing illness and death in domestic animals and humans is a cause of concern. In 2009, RNA sequences of three novel viruses in phylogenetic relationship to known henipaviruses were detected in African straw-colored fruit bats (''Eidolon helvum'') in Ghana. The finding of these novel henipaviruses outside Australia and Asia indicates that the region of potential endemicity of henipaviruses may be worldwide. These African henipaviruses are slowly being characterised. ''Nipah virus, Nipa ...
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Faculty Of Medicine, University Of Malaya
The Faculty of Medicine, University of Malaya (commonly known as the UM Medical School, FoM UM, UM Medicine or Malaya Medicine) is one of the thirteen faculties of the University of Malaya (UM). It was officially established in September 1962 after the establishment of the university's Kuala Lumpur campus; it was the first medical school established in Malaysia. The faculty is well-known for its medical education and research, especially in the discovery of the Nipah virus (1998–1999 Malaysia Nipah virus outbreak). The faculty is widely regarded as the top medical school in Malaysia, being placed at No. 145 in the world in the subject of Medicine in the QS World University Subject Rankings 2021; this makes it the highest ranked medical school in Malaysia and the third highest in Southeast Asia. History The Faculty of Medicine was first established in Singapore as the Straits Settlements and the Federated Malay States Government Medical School in 1905, which traine ...
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National Public Radio
National Public Radio (NPR, stylized in all lowercase) is an American privately and state funded nonprofit media organization headquartered in Washington, D.C., with its NPR West headquarters in Culver City, California. It differs from other non-profit membership media organizations such as the Associated Press, in that it was established by an act of Congress. Most of its member stations are owned by non-profit organizations, including public school districts, colleges, and universities. It serves as a national Radio syndication, syndicator to a network of over 1,000 public radio List of NPR stations, stations in the United States. , NPR employed 840 people. NPR produces and distributes news and cultural programming. The organization's flagship shows are two drive time, drive-time news broadcasts: ''Morning Edition'' and the afternoon ''All Things Considered'', both carried by most NPR member stations, and among the List of most-listened-to radio programs, most popular radio p ...
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Immunohistochemistry
Immunohistochemistry (IHC) is the most common application of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues. IHC takes its name from the roots "immuno", in reference to antibodies used in the procedure, and "histo", meaning tissue (compare to immunocytochemistry). Albert Coons conceptualized and first implemented the procedure in 1941. Visualising an antibody-antigen interaction can be accomplished in a number of ways, mainly either of the following: * ''Chromogenic immunohistochemistry'' (CIH), wherein an antibody is conjugated to an enzyme, such as peroxidase (the combination being termed immunoperoxidase), that can catalyse a colour-producing reaction. * '' Immunofluorescence'', where the antibody is tagged to a fluorophore, such as fluorescein or rhodamine. Immunohistochemical staining is widely used in the dia ...
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Immunoglobulin G
Immunoglobulin G (Ig G) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG antibody has two paratopes. Function Antibodies are major components of humoral immunity. IgG is the main type of antibody found in blood and extracellular fluid, allowing it to control infection of body tissues. By binding many kinds of pathogens such as viruses, bacteria, and fungi, IgG protects the body from infection. It does this through several mechanisms: * IgG-mediated binding of pathogens causes their immobilization and binding together via agglutination; IgG coating of pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the elimination of the pathogen itself; * IgG activates all the classical pathway of the complement system, a cascade of immune protein pr ...
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Cerebrospinal Fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the brain, and absorbed in the arachnoid granulations. There is about 125 mL of CSF at any one time, and about 500 mL is generated every day. CSF acts as a shock absorber, cushion or buffer, providing basic mechanical and immunological protection to the brain inside the skull. CSF also serves a vital function in the cerebral autoregulation of cerebral blood flow. CSF occupies the subarachnoid space (between the arachnoid mater and the pia mater) and the ventricular system around and inside the brain and spinal cord. It fills the ventricles of the brain, cisterns, and sulci, as well as the central canal of the spinal cord. There is also a connection from the subarachnoid space to the bony labyrinth of the inner ear via the perilymphat ...
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Throat Swab
In medicine, sampling is gathering of matter from the body to aid in the process of a medical diagnosis and/or evaluation of an indication for treatment, further medical tests or other procedures. In this sense, the sample is the gathered matter, and the sampling tool or sampler is the person or material to collect the sample. Sampling is a prerequisite for many medical tests, but generally not for medical history, physical examination and radiologic tests. By sampling technique *Obtaining excretions or materials that leave the body anyway, such as urine, stool, sputum, or vomitus, by direct collection as they exit. A sample of saliva can also be collected from the mouth. Excision (cutting out), a surgical method for the removal of solid or soft tissue samples. *Puncture (also called ''centesis'') followed by aspiration is the main method used for sampling of many types of tissues and body fluids. Examples are thoracocentesis to sample pleural fluid, and amniocentesis to ...
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Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ...
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Nipah
NIPA, Nipa or nipah may refer to: * Shamim Ara Nipa, Bangladeshi dancer and choreographer * Nipa hut, a type of stilt house indigenous to the cultures of the Philippines * Nipah virus, a Henipavirus NIPA * National Income and Product Accounts, one of the main sources of data on general economic activity in the United States * National IT Industry Promotion Agency, an IT industry promotion organization operated by the Government of South Korea * National Institute of Public Administration (Malaysia), a Malaysian government agency responsible for the training of civil servants * National Institute of Public Administration (Pakistan), a school to impart training for Civil Servants of Pakistan * NIPA1, a gene in humans that encodes Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 ** NIPA2, a gene in humans that encodes Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 Plants * Nipa palm, '' Nypa fruticans'' * Nipa grass, ''Distichlis palmeri'' * ...
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Zoonotic
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. Typically, the first infected human transmits the infectious agent to at least one other human, who, in turn, infects others. Major modern diseases such as Ebola virus disease and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Most strains of influenza that infect humans are human diseases, although many strains of bird flu and swine flu are zoonoses; these viruses occasionally recombine with human strains of the flu and can cause pandemics such as the 1918 Spanish flu or the 2009 swine flu. ''Taenia solium'' infection is one of the neglected tropical diseases with public health and veterinary concern in ende ...
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Encephalitis
Encephalitis is inflammation of the brain. The severity can be variable with symptoms including reduction or alteration in consciousness, headache, fever, confusion, a stiff neck, and vomiting. Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing. Causes of encephalitis include viruses such as herpes simplex virus and rabies virus as well as bacteria, fungi, or parasites. Other causes include autoimmune diseases and certain medications. In many cases the cause remains unknown. Risk factors include a weak immune system. Diagnosis is typically based on symptoms and supported by blood tests, medical imaging, and analysis of cerebrospinal fluid. Certain types are preventable with vaccines. Treatment may include antiviral medications (such as acyclovir), anticonvulsants, and corticosteroids. Treatment generally takes place in hospital. Some people require artificial respiration. Once the immediate problem is under co ...
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