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National Weight Control Registry
The National Weight Control Registry is a research study that includes people (18 years or older) who have lost at least 13.6 kg (30 lbs) of weight and kept it off for at least one year. There are currently over 10,000 members enrolled in the study, making it perhaps the largest study of weight loss ever conducted. Members complete annual questionnaires about their current weight, diet and exercise habits, and behavioral strategies for weight loss maintenance. The National Weight Control Registry is coordinated through the Miriam Hospital's "Weight Control and Diabetes Research Center" in Providence, Rhode Island. It was founded and is currently overseen by Dr. Rena Wing at Brown University and Dr. James Hill at University of Colorado. Demographics The registry is composed of approximately 80% women. The “average” female participant is 45 years old and currently 145 pounds while the average man is 49 years old and 190 pounds. On average, registry members have lost abou ...
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Miriam Hospital
The Miriam Hospital is a private, not-for-profit hospital at 164 Summit Avenue in Providence, in the U.S. state of Rhode Island. It is a major teaching affiliate of the Warren Alpert Medical School of Brown University. History In 1902, a handful of women began collecting coins to raise $1,000 for the down payment on "a place to care for the indigent sick of the Jewish faith." Since then, extraordinary generosity has been the catalyst for The Miriam Hospital. To fulfill the women's dream, 450 people joined their cause. The women went door to door, raising $80,000 in just four weeks. Thanks to their efforts, the first Miriam Hospital opened in 1926 with 63 beds and 14 bassinets. Remarkably, the community stepped forward again. Only a year later, another $82,000 was raised to help defray the "burdens of caring for charity patients." These first fundraising efforts were only the beginning of a partnership between The Miriam Hospital and the community; a relationship that has endured ...
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Dieting
Dieting is the practice of eating food in a regulated way to decrease, maintain, or increase body weight, or to prevent and treat diseases such as diabetes and obesity. As weight loss depends on calorie intake, different kinds of calorie-reduced diets, such as those emphasising particular macronutrients (low-fat, low-carbohydrate, etc.), have been shown to be no more effective than one another. As weight regain is common, diet success is best predicted by long-term adherence. Regardless, the outcome of a diet can vary widely depending on the individual. The first popular diet was "Banting", named after William Banting. In his 1863 pamphlet, ''Letter on Corpulence, Addressed to the Public'', he outlined the details of a particular low-carbohydrate, low-calorie diet that led to his own dramatic weight loss. Some guidelines recommend dieting to lose weight for people with weight-related health problems, but not for otherwise healthy people. One survey found that almost half o ...
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Human Weight
Human body weight is a person's mass or weight. Strictly speaking, body weight is the measurement of weight without items located on the person. Practically though, body weight may be measured with clothes on, but without shoes or heavy accessories such as mobile phones and wallets, and using manual or digital weighing scales. Excess or reduced body weight is regarded as an indicator of determining a person's health, with body volume measurement providing an extra dimension by calculating the distribution of body weight. Average adult human weight varies by continent, from about in Asia and Africa to about in North America, with men on average weighing more than women. Estimation in children There are a number of methods to estimate weight in children for circumstances (such as emergencies) when actual weight cannot be measured. Most involve a parent or health care provider guessing the child's weight through weight-estimation formulas. These formulas base their findings o ...
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Obesity
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are diet, physical activity, automation, urbanization, genetic susceptibility, medications, mental disorders, economic policies, endocrine disorders, and exposure to endocrine-disrupting chemicals. While a majority of obese individuals at any given time are attempting to ...
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Clinical Research
Clinical research is a branch of healthcare science that determines the safety and effectiveness ( efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease. Clinical research is different from clinical practice. In clinical practice established treatments are used, while in clinical research evidence is collected to establish a treatment. Overview The term "clinical research" refers to the entire bibliography of a drug/device/biologic, in fact any test article from its inception in the lab to its introduction to the consumer market and beyond. Once the promising candidate or the molecule is identified in the lab, it is subjected to pre-clinical studies or animal studies where different aspects of the test article (including its safety toxicity if applicable and efficacy, if possible at this early stage) are studied. In the United States ...
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