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N-methyltransferase
N-methyltransferase may refer to: *(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase * 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase * Amine N-methyltransferase * Anthranilate N-methyltransferase * (cytochrome c)-arginine N-methyltransferase * (myelin basic protein)-arginine N-methyltransferase * Calmodulin-lysine N-methyltransferase *Carnosine N-methyltransferase * (S)-coclaurine-N-methyltransferase * Dimethylhistidine N-methyltransferase *Glycine N-methyltransferase *Guanidinoacetate N-methyltransferase *Histamine N-methyltransferase *Histone methyltransferase * (cytochrome c)-lysine N-methyltransferase *(ribulose-bisphosphate carboxylase)-lysine N-methyltransferase *Methylamine—glutamate N-methyltransferase * Nicotinamide N-methyltransferase *Nicotinate N-methyltransferase *Phenylethanolamine N-methyltransferase *Phosphatidylethanolamine N-methyltransferase *Phosphatidyl-N-methylethanolamine N-methyltransferase *Phosphoethanolamine N-methyltransf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phosphatidylethanolamine N-methyltransferase
Phosphatidylethanolamine N-methyltransferase (abbreviated PEMT) is a transferase enzyme () which converts phosphatidylethanolamine (PE) to phosphatidylcholine (PC) in the liver. In humans it is encoded by the ''PEMT'' gene within the Smith–Magenis syndrome region on chromosome 17. While the CDP-choline pathway, in which choline obtained either by dietary consumption or by metabolism of choline-containing lipids is converted to PC, accounts for approximately 70% of PC biosynthesis in the liver, the PEMT pathway has been shown to have played a critical evolutionary role in providing PC during times of starvation. Furthermore, PC made via PEMT plays a wide range of physiological roles, utilized in choline synthesis, hepatocyte membrane structure, bile secretion, and very low-density lipoprotein (VLDL) secretion. Nomenclature Phosphatidylethanolamine N-methyltransferase is also known as lipid methyl transferase, LMTase, phosphatidylethanolamine methyltransferase, phosphati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylethanolamine N-methyltransferase
Phenylethanolamine ''N''-methyltransferase (PNMT) is an enzyme found primarily in the adrenal medulla that converts norepinephrine (noradrenaline) to epinephrine (adrenaline). It is also expressed in small groups of neurons in the human brain and in selected populations of cardiomyocytes. Structure PNMT is a protein whose encoding gene is found on chromosome 17 in humans. It consists of 4 exons and is a 30 kDa protein. It shares many properties found among the other methyltransferases. It is closest in sequence to glycine-''N''-methyl transferase ( GNMT). It also shares many structural properties like the shape of the folding lip with catechol-O-methyl transferase (COMT), though it shares less sequence identity. Several features of the structure like this folding lip suggest that PNMT is a recent adaptation to the catecholamine synthesizing enzyme family, evolving later than COMT, but before other methyltransferases like GNMT. ''S''-adenosyl-L-methionine (SAM) is a requir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycine N-methyltransferase
In enzymology, a glycine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + glycine \rightleftharpoons S-adenosyl-L-homocysteine + sarcosine Thus, the substrates of this enzyme are S-adenosyl methionine and glycine, whereas its two products are S-adenosylhomocysteine and sarcosine. Glycine N-methyltransferase belongs to the family of methyltransferase enzymes. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:glycine N-methyltransferase. Other names in common use include glycine methyltransferase, S-adenosyl-L-methionine:glycine methyltransferase, and GNMT. This family of enzymes participates in the metabolism of multiple amino acids. References * * * * * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Putrescine N-methyltransferase
In enzymology, a putrescine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + putrescine \rightleftharpoons S-adenosyl-L-homocysteine + N-methylputrescine Thus, the two substrates of this enzyme are S-adenosyl methionine and putrescine, whereas its two products are S-adenosylhomocysteine and N-methylputrescine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:putrescine N-methyltransferase. This enzyme is also called putrescine methyltransferase. This enzyme participates in alkaloid biosynthesis ii. This enzyme is important in the synthesis of many plant alkaloids. It evolved from spermidine synthase Spermidine synthase is an enzyme () that catalyzes the transfer of the propylamine group from ''S''-adenosylmethioninamine to putrescine in the biosynthesis of spermidine. The systematic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase
In enzymology, a 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + 3-hydroxy-16-methoxy-2,3-dihydrotabersonine \rightleftharpoons S-adenosyl-L-homocysteine + deacetoxyvindoline Thus, the two substrates of this enzyme are S-adenosyl methionine and 3-hydroxy-16-methoxy-2,3-dihydrotabersonine, whereas its two products are S-adenosylhomocysteine and deacetoxyvindoline. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase. Other names in commo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guanidinoacetate N-methyltransferase
Guanidinoacetate N-methyltransferase () is an enzyme that catalyzes the chemical reaction and is encoded by gene ''GAMT'' located on chromosome 19p13.3. :S-adenosyl-L-methionine + guanidinoacetate \rightleftharpoons S-adenosyl-L-homocysteine + creatine Thus, the two substrates of this enzyme are S-adenosyl methionine and guanidinoacetate, whereas its two products are S-adenosylhomocysteine and creatine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase. Other names in common use include GA methylpherase, guanidinoacetate methyltransferase, guanidinoacetate transmethylase, methionine-guanidinoacetic transmethylase, and guanidoacetate methyltransferase. This enzyme participates in glycine, serine and threonine metabolism and arginine and proline metabolism. The protein encoded by this gene is a methyl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase
In enzymology, a (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase is an enzyme that catalyzes the chemical reaction: : S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline \rightleftharpoons S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline This enzyme participates in alkaloid biosynthesis. Nomenclature This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase. This enzyme is also called norreticuline N-methyltransferase. References EC 2.1.1 Enzymes of unkno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carnosine N-methyltransferase
In enzymology, a carnosine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + carnosine \rightleftharpoons S-adenosyl-L-homocysteine + anserine Thus, the two substrates of this enzyme are S-adenosyl methionine and carnosine, whereas its two products are S-adenosylhomocysteine and anserine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:carnosine N-methyltransferase. This enzyme participates in histidine metabolism. Gene The genes encoding carnosine ''N''-methyltransferase activity have been identified by Jakub Drozak and coworkers in 201 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
(S)-tetrahydroprotoberberine N-methyltransferase
In enzymology, a (S)-tetrahydroprotoberberine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine \rightleftharpoons S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine Thus, the two substrates of this enzyme are S-adenosyl methionine and (S)-7,8,13,14-tetrahydroprotoberberine, whereas its two products are S-adenosylhomocysteine and cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthranilate N-methyltransferase
In enzymology, an anthranilate N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + anthranilate \rightleftharpoons S-adenosyl-L-homocysteine + N-methylanthranilate Thus, the two substrates of this enzyme are S-adenosyl methionine and anthranilate, whereas its two products are S-adenosylhomocysteine and N-methylanthranilate. This enzyme belongs to the family of transferase A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of di ...s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:anthranilate N-methyltransferase. This enzyme is also called anthranilic acid N-methyltransferase. This enzyme participates in acridone alkaloid biosynthesis. References ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
(S)-coclaurine-N-methyltransferase
In enzymology, a (S)-coclaurine-N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + (S)-coclaurine \rightleftharpoons S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine Thus, the two substrates of this enzyme are S-adenosyl methionine and (S)-coclaurine, whereas its two products are S-adenosylhomocysteine and (S)-N-methylcoclaurine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase. This enzyme participates in alkaloid biosynthesis i Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar st .... References * EC 2.1.1 Enzymes of unknown structure {{2.1-e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calmodulin-lysine N-methyltransferase
In enzymology, a calmodulin-lysine N-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + calmodulin L-lysine \rightleftharpoons S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine Thus, the two substrates of this enzyme are S-adenosyl methionine and calmodulin L-lysine, whereas its two products are S-adenosylhomocysteine and calmodulin N6-methyl-L-lysine. This enzyme belongs to the family of transferase A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of di ...s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase. Other names in common use include S-adenosylmethionine:calmodulin (lysine) N-methyltransferas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
