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N-methyl-N-propyltryptamine
Methylpropyltryptamine (MPT; ''N''-methyl-''N''-propyltryptamine) is a tryptamine. It is a homolog of methylethyltryptamine. An analytical method for its detection has been reported. In 2019, Chadeayne et al. published the crystal structure of MPT. The authors describe the structure as "...a single molecule in the asymmetric unit, with an indole group that demonstrates a mean deviation from planarity of 0.015 A°." See also * 4-HO-MPT 4-Hydroxy-''N''-methyl-''N''-propyltryptamine, commonly known as 4-HO-MPT or meprocin, is a psychedelic drug in the tryptamine class of chemical compounds and is a higher homologue of the naturally occurring substituted tryptamine psilocin as wel ... References Tryptamines Tertiary amines {{psychoactive-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tryptamines
Substituted tryptamines, or serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself. The molecular structures of all tryptamines contain an indole ring, joined to an amino (NH2) group via an ethyl (−CH2–CH2−) sidechain. In substituted tryptamines, the indole ring, sidechain, and/or amino group are modified by substituting another group for one of the hydrogen (H) atoms. Well-known tryptamines include serotonin, an important neurotransmitter, and melatonin, a hormone involved in regulating the sleep-wake cycle. Tryptamine alkaloids are found in fungi, plants and animals; and sometimes used by humans for the neurological or psychotropic effects of the substance. Prominent examples of tryptamine alkaloids include psilocybin (from "psilocybin mushrooms") and DMT. In South America, dimethyltryptamine is obtained from numerous plant sources, like chacruna, and it is often used in ayahuasca brews. Many synthetic tryptamines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
4-HO-MPT
4-Hydroxy-''N''-methyl-''N''-propyltryptamine, commonly known as 4-HO-MPT or meprocin, is a psychedelic drug in the tryptamine class of chemical compounds and is a higher homologue of the naturally occurring substituted tryptamine psilocin as well as being the 4-hydroxyl analog of MPT. History 4-HO-MPT was first synthesized and bioassayed by biochemist Alexander Shulgin and written about in his 1994 book ''TiHKAL''. Dosage and duration For psychedelic effects, the dosage and duration are listed as "unknown" in TiHKAL. Effects Very little data exists about the pharmacological properties, metabolism, and toxicity of 4-HO-MPT. In a single trial of 8 mg orally of 4-HO-MPT HCl from TiHKAL, it is described as producing visual distortion, vertigo, and slight insomnia. Legal status 4-HO-MPT is not scheduled by the United Nations' Convention on Psychotropic Substances. United States 4-HO-MPT is not scheduled at the federal level in the United States, but it is possible that 4- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tryptamine
Tryptamine is an indolamine metabolite of the essential amino acid, tryptophan. The chemical structure is defined by an indole ─ a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the first one being the heterocyclic nitrogen). The structure of tryptamine is a shared feature of certain aminergic neuromodulators including melatonin, serotonin, bufotenin and psychedelic derivatives such as dimethyltryptamine (DMT), psilocybin, psilocin and others. Tryptamine has been shown to activate trace amine-associated receptors expressed in the mammalian brain, and regulates the activity of dopaminergic, serotonergic and glutamatergic systems. In the human gut, symbiotic bacteria convert dietary tryptophan to tryptamine, which activates 5-HT4 receptors and regulates gastrointestinal motility. Multiple tryptamine-derived drugs have been developed to treat migraines, while trace amine-associated receptors are being explored as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homolog (chemistry)
In chemistry, homology is the appearance of homologues. A homologue (also spelled as homolog) is a compound belonging to a series of compounds differing from each other by a repeating unit, such as a methylene bridge −−, a peptide residue, etc. A homolog is a special case of an analog. Examples are alkanes and compounds with alkyl side chains of different length (the repeating unit being a methylene group -CH2-). Periodic table On the periodic table, homologous elements share many electrochemical properties and appear in the same group (column) of the table. For example, all noble gases are colorless, monatomic gases with very low reactivity. These similarities are due to similar structure in their outer shells of valence electrons. Mendeleev used the prefix eka- for an unknown element below a known one in the same group. See also * Homologous series * Analog * Congener * Structure–activity relationship The structure–activity relationship (SAR) is the relations ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Methyl-N-ethyltryptamine
''N''-Methyl-''N''-ethyltryptamine (MET) is a psychedelic tryptamine. It is closely related to DMT and DET. There is very little information on the human pharmacology or toxicity Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a subs ... of MET. The freebase is believed to be active via vaporization at 15 mg.Erowid's_online_version_of_TiHKAL,_a_book_about_Tryptamines Entheogens.html" ;"title="TiHKAL, a book about Tryptamines">TiHKAL">Erowid's online version of TiHKAL, a book about Tryptamines Entheogens">TiHKAL, a book about Tryptamines">TiHKAL">Erowid's online version of TiHKAL, a book about Tryptamines Entheogens Psychedelic tryptamines Designer drugs {{hallucinogen-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
