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N-Ethylheptedrone
''N''-Ethylheptedrone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethcathinone, ''N''-ethylbuphedrone and ''N''-ethylhexedrone but with a longer pentyl side chain. It was first identified in Hungary in 2019, and has since been reported in New Zealand. See also * α-PEP * 3F-NEH * 4F-POP * Ephylone * N-Ethylpentedrone * N-Ethylhexylone * N-Ethylheptylone ''N''-Ethylheptylone (HEP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethylone, eutylone, ephylone and ''N''-ethylhexylone but with a longer heptyl ... References Designer drugs Cathinones {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Cathinone
Substituted cathinones, which include some stimulants and entactogens, are derivatives of cathinone. They feature a phenethylamine core with an alkyl group attached to the alpha carbon, and a ketone group attached to the beta carbon, along with additional substitutions. Cathinone occurs naturally in the plant khat whose leaves are chewed as a recreational drug. List of substituted cathinones The derivatives may be produced by substitutions at four locations of the cathinone molecule: * R1 = hydrogen, or any combination of one or more alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents * R2 = hydrogen or any alkyl group * R3 = hydrogen, any alkyl group, or incorporation in a cyclic structure * R4 = hydrogen, any alkyl group, or incorporation in a cyclic structure The following table displays notable derivatives that have been reported: Legality On 2 April 2010, the Advisory Council on the Misuse of Drugs in the UK announced that a broad structure-based ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Ethylbuphedrone
''N''-Ethylbuphedrone (also known as NEB) is a stimulant of the cathinone class that has been sold as a designer drug. It is the β-ketone analogue of ''N'',''alpha''-diethylphenylethylamine. Legal status As of October 2015 NEB is a controlled substance in China. See also * 4-Methylbuphedrone * 4-Methylethcathinone * Buphedrone * Ethcathinone * Etilamfetamine * N-Ethylpentedrone * N-Ethylhexedrone * N-Ethylheptedrone ''N''-Ethylheptedrone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethcathinone, ''N''-ethylbuphedrone and ''N''-ethylhexedrone but with a longer p ... References Stimulants Cathinones Designer drugs Norepinephrine-dopamine releasing agents {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Ethylhexedrone
''N''-Ethylhexedrone (also known as α-ethylaminocaprophenone, ''N''-ethylnorhexedrone, hexen, and NEH) is a stimulant of the cathinone class that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI) with IC50 values of 0.0978 and 0.0467 μM, respectively. ''N''-Ethylhexedrone was first mentioned in a series of patents by Boehringer Ingelheim in the 1960s which led to the development of the better-known drug methylenedioxypyrovalerone (MDPV). Since the mid-2010s, ''N''-ethylhexedrone has been sold online as a designer drug. In 2018, ''N''-ethylhexedrone was the second most common drug of the cathinone class to be identified in Drug Enforcement Administration seizures. ''N''-Ethylhexedrone was first synthesized by Boehringer Ingelheim in 1964. It appears to have emerged on the online research chemical market in late 2015. It is an example of a novel psychoactive substance specifically chosen to mimic the features of prohibited substances and bypass drug laws. It is one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Ethylpentedrone
''N''-Ethylpentedrone (also known as α-ethylaminopentiophenone, α-EAPP, α-ethylaminovalerophenone, ''N''-ethylnorpentedrone, and NEP) is a chemical compound of the substituted cathinone class. Since the mid-2010s, NEP has been sold online as a designer drug. It is the ''N''-ethyl analog of pentedrone. Legal status NEP is illegal in Japan and China, and is classified as a '"potentially harmful substance"', thus, controlled, but not banned in Sweden. See also * Pentedrone * 4-Methylethcathinone * 4'-Methyl-α-pyrrolidinohexiophenone * α-Pyrrolidinohexiophenone * Ethcathinone * ''N''-Ethylbuphedrone * N-Ethylhexedrone * N-Ethylheptedrone * Ephylone ''N''-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine, βk-ethyl-K, βk-EBDP, ephylone) is a substituted cathinone and stimulant drug which was developed in the 1960s. It has been reported as a novel designer drug in several countries in ... References {{DEFAULTSORT:Ethylhexedrone, N- Cathinones Designer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Ethylheptylone
''N''-Ethylheptylone (HEP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethylone, eutylone, ephylone and ''N''-ethylhexylone but with a longer heptyl side chain. It was first reported in Sweden in 2019. See also * α-PEP * 3F-NEH * 4F-PV9 * MDPHP * N-Ethylheptedrone ''N''-Ethylheptedrone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethcathinone, ''N''-ethylbuphedrone and ''N''-ethylhexedrone but with a longer p ... References Designer drugs Cathinones {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Designer Drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Designer drugs include psychoactive substances that have been designated by the European Union as new psychoactive substances (NPS) as well as analogs of performance-enhancing drugs such as designer steroids. Some of these were originally synthesized by academic or industrial researchers in an effort to discover more potent derivatives with fewer side effects, and shorter duration (and possibly also because it is easier to apply for patents for new molecules) and were later co-opted for recreational use. Other designer drugs were prepared for the first time in clandestine laboratories. Because the efficacy and safety of these substances have not been thoroughly evaluated in animal and human trials, the use of some of these drugs may result i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stimulant
Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have Sympathomimetic drug, sympathomimetic effects. Stimulants are widely used throughout the world as prescription medicines as well as without a prescription (either legally or Prohibition (drugs), illicitly) as performance-enhancing substance, performance-enhancing or recreational drug use, recreational drugs. Among narcotics, stimulants produce a noticeable crash or ''Comedown (drugs), comedown'' at the end of their effects. The most frequently prescribed stimulants as of 2013 were lisdexamfetamine (Vyvanse), methylphenidate (Ritalin), and amphetamine (Adderall). It was estimated in 2015 that the percentage of the world population that had used cocaine during a year was 0.4%. For the category "amphetamines and p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homology (chemistry)
In chemistry, homology is the appearance of homologues. A homologue (also spelled as homolog) is a compound belonging to a series of compounds differing from each other by a repeating unit, such as a methylene bridge −−, a peptide residue, etc. A homolog is a special case of an analog. Examples are alkanes and compounds with alkyl side chains of different length (the repeating unit being a methylene group -CH2-). Periodic table On the periodic table, homologous elements share many electrochemical properties and appear in the same group (column) of the table. For example, all noble gases are colorless, monatomic gases with very low reactivity. These similarities are due to similar structure in their outer shells of valence electrons. Mendeleev used the prefix eka- for an unknown element below a known one in the same group. See also * Homologous series * Analog Analog or analogue may refer to: Computing and electronics * Analog signal, in which information is enco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethcathinone
Ethcathinone, also known as ethylpropion or ETH-CAT, is a stimulant drug of the phenethylamine, amphetamine, and cathinone chemical classes. It is an active metabolite of the prodrug diethylcathinone and is fully responsible for its effects. Ethcathinone has been identified as an ingredient in both quasi-legal "party pills", and, along with mephedrone, has also been reported as having been sold as "ecstasy" in the Australian city of Cairns. Pharmacology The pharmacology for ethcathinone appeared alongside other psychostimulants in a paper by Rothman and Baumann in 2006. The predominant two modes of action for ethcathinone is as a moderately active releaser of noradrenaline (EC50 = 99.3nM); however it is only a relatively weak inhibitor of dopamine reuptake (Ki = 1,014nM). Since diethylcathinone appears to be an inactive prodrug and only becomes active after it has been further metabolized to ethcathinone, it thereby would appear rational to consider that ethcathinone would a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pentyl
Pentyl is a five-carbon alkyl group or substituent with chemical formula -C5H11. It is the substituent form of the alkane pentane. In older literature, the common non-systematic name amyl was often used for the pentyl group. Conversely, the name pentyl was used for several five-carbon branched alkyl groups, distinguished by various prefixes. The nomenclature has now reversed, with "amyl" being more often used to refer to the terminally branched group also called isopentyl, as in amobarbital. A cyclopentyl group is a ring with the formula -C5H9. The name is also used for the pentyl radical, a pentyl group as an isolated molecule. This free radical is only observed in extreme conditions. Its formula is often written "•" or "• " to indicate that it has one unsatisfied valence bond. Older "pentyl" groups The following names are still used sometimes: Pentyl radical The free radical pentyl was studied by J. Pacansky and A. Gutierrez in 1983. The radical was obtained by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3F-NEH
3F-NEH (3-Fluoro-N-Ethylhexedrone) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Sweden in October 2020. See also * 3-Fluoromethamphetamine * 3-Fluoromethcathinone * 3F-NEB * 3F-PiHP * 3F-PVP * 3F-Phenmetrazine * N-Ethylhexedrone * N-Ethylhexylone ''N''-Ethylhexylone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Poland in August 2019. It is illegal in Taiwan since July 2020, where it had been sold mixed with plant ... References Cathinones Designer drugs Serotonin-norepinephrine-dopamine releasing agents Fluoroarenes {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
