Monidovirineae
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Monidovirineae
''Alphamononivirus'' is a genus of enveloped, positive-strand RNA viruses in the order ''Nidovirales'' which infect planarian flatworms. Member virus planarian secretory cell nidovirus (PSCNV) has the largest known nonsegmented RNA genome of 41.1kb of any RNA virus. The genus is monotypic In biology, a monotypic taxon is a taxonomic group (taxon) that contains only one immediately subordinate taxon. A monotypic species is one that does not include subspecies or smaller, infraspecific taxa. In the case of genera, the term "unispec .... It contains the subgenus ''Dumedivirus'', which contains only one species, ''Planidovirus 1''. ''Alphamononivirus'' is also the only member of the subfamily ''Mononivirinae'', which in turn is the only member of family ''Mononiviridae'', which likewise is the only member of the ''Monidovirineae'' suborder. References {{Taxonbar, from=Q57919736, from2=Q57880048, from3=Q57773890, from4=Q57751775, from5=Q57751030, from6=Q57743968 Virus gener ...
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Dumedivirus
''Alphamononivirus'' is a genus of enveloped, positive-strand RNA viruses in the order ''Nidovirales'' which infect planarian flatworms. Member virus planarian secretory cell nidovirus (PSCNV) has the largest known nonsegmented RNA genome of 41.1kb of any RNA virus. The genus is monotypic In biology, a monotypic taxon is a taxonomic group (taxon) that contains only one immediately subordinate taxon. A monotypic species is one that does not include subspecies or smaller, infraspecific taxa. In the case of genera, the term "unispec .... It contains the subgenus ''Dumedivirus'', which contains only one species, ''Planidovirus 1''. ''Alphamononivirus'' is also the only member of the subfamily ''Mononivirinae'', which in turn is the only member of family ''Mononiviridae'', which likewise is the only member of the ''Monidovirineae'' suborder. References {{Taxonbar, from=Q57919736, from2=Q57880048, from3=Q57773890, from4=Q57751775, from5=Q57751030, from6=Q57743968 Virus gene ...
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Nidovirales
''Nidovirales'' is an order of enveloped, positive-strand RNA viruses which infect vertebrates and invertebrates. Host organisms include mammals, birds, reptiles, amphibians, fish, arthropods, molluscs, and helminths. The order includes the families ''Coronaviridae'', ''Arteriviridae, Roniviridae,'' and ''Mesoniviridae''. Member viruses have a viral envelope and a positive-sense, single-stranded RNA genome which is capped and polyadenylated. Nidoviruses are named for the Latin ''nidus'', meaning nest, as all viruses in this order produce a 3' co-terminal nested set of subgenomic mRNAs during infection. Virology Structure Nidoviruses have a viral envelope and a positive-sense, single-stranded RNA genome which is capped and polyadenylated. The group expresses structural proteins separately from the nonstructural ones. The structural proteins are encoded at the 3’ region of the genome and are expressed from a set of subgenomic mRNAs. Member viruses encode one main protei ...
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Planidovirus 1
Planarian secretory cell nidovirus (PSCNV) is a virus of the species ''Planidovirus 1'', a nidovirus notable for its extremely large genome. At 41.1 kilobases, it is the largest known genome of an RNA virus. It was discovered by inspecting the transcriptomes of the planarian flatworm '' Schmidtea mediterranea'' and is the first known RNA virus infecting planarians. It was first described in 2018. Genome and expression The PSCNV genome is 41.1 kilobases long, the largest known genome in an RNA virus. It is substantially larger than coronaviruses, another group of nidoviruses known for large genomes, which are typically in the 27-32kb range. PSCNV has an unusual genomic organization consisting of a single extremely large open reading frame (ORF) which encodes a polyprotein of 13,556 amino acids - the largest protein known to be encoded by an RNA virus. Bioinformatics analysis of the genome suggests it is organized similarly to canonical nidovirus genomes, in which ORF1a and ORF ...
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Viral Envelope
A viral envelope is the outermost layer of many types of viruses. It protects the genetic material in their life cycle when traveling between host cells. Not all viruses have envelopes. Numerous human pathogenic viruses in circulation are encased in lipid bilayers, and they infect their target cells by causing the viral envelope and cell membrane to fuse. Although there are effective vaccines against some of these viruses, there is no preventative or curative medicine for the majority of them. In most cases, the known vaccines operate by inducing antibodies that prevent the pathogen from entering cells. This happens in the case of enveloped viruses when the antibodies bind to the viral envelope proteins. The membrane fusion event that triggers viral entrance is caused by the viral fusion protein. Many enveloped viruses only have one protein visible on the surface of the particle, which is required for both mediating adhesion to the cell surface and for the subsequent membrane fusi ...
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Positive-strand RNA Virus
Positive-strand RNA viruses (+ssRNA viruses) are a group of related viruses that have positive-sense, single-stranded genomes made of ribonucleic acid. The positive-sense genome can act as messenger RNA (mRNA) and can be directly translated into viral proteins by the host cell's ribosomes. Positive-strand RNA viruses encode an RNA-dependent RNA polymerase (RdRp) which is used during replication of the genome to synthesize a negative-sense antigenome that is then used as a template to create a new positive-sense viral genome. Positive-strand RNA viruses are divided between the phyla ''Kitrinoviricota'', ''Lenarviricota'', and ''Pisuviricota'' (specifically classes ''Pisoniviricetes'' and '' Stelpavirictes'') all of which are in the kingdom '' Orthornavirae'' and realm '' Riboviria''. They are monophyletic and descended from a common RNA virus ancestor. In the Baltimore classification system, +ssRNA viruses belong to Group IV. Positive-sense RNA viruses include pathogen ...
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Planarian
A planarian is one of the many flatworms of the traditional class Turbellaria. It usually describes free-living flatworms of the order Tricladida (triclads), although this common name is also used for a wide number of free-living platyhelminthes. Planaria are common to many parts of the world, living in both saltwater and freshwater ponds and rivers. Some species are terrestrial and are found under logs, in or on the soil, and on plants in humid areas. The triclads are characterized by triply branched intestine and anteriorly situated ovaries, next to the brain. Today the order Tricladida is split into three suborders, according to their phylogenetic relationships: Maricola, Cavernicola and Continenticola. Formerly, the Tricladida was split according to habitats: Maricola, which is marine; Paludicola which inhabits freshwater; and Terricola, which is land-dwelling. Planaria exhibit an extraordinary ability to regenerate lost body parts. For example, a planarian split lengt ...
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Flatworm
The flatworms, flat worms, Platyhelminthes, or platyhelminths (from the Greek πλατύ, ''platy'', meaning "flat" and ἕλμινς (root: ἑλμινθ-), ''helminth-'', meaning "worm") are a phylum of relatively simple bilaterian, unsegmented, soft-bodied invertebrates. Unlike other bilaterians, they are acoelomates (having no body cavity), and have no specialized circulatory and respiratory organ (anatomy), organs, which restricts them to having flattened shapes that allow oxygen and nutrients to pass through their bodies by diffusion. The digestive cavity has only one opening for both ingestion (intake of nutrients) and egestion (removal of undigested wastes); as a result, the food cannot be processed continuously. In traditional medicinal texts, Platyhelminthes are divided into Turbellaria, which are mostly non-parasitic animals such as planarians, and three entirely parasitic groups: Cestoda, Trematoda and Monogenea; however, since the turbellarians have since been prove ...
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Planarian Secretory Cell Nidovirus
Planarian secretory cell nidovirus (PSCNV) is a virus of the species ''Planidovirus 1'', a nidovirus notable for its extremely large genome. At 41.1 kilobases, it is the largest known genome of an RNA virus. It was discovered by inspecting the transcriptomes of the planarian flatworm '' Schmidtea mediterranea'' and is the first known RNA virus infecting planarians. It was first described in 2018. Genome and expression The PSCNV genome is 41.1 kilobases long, the largest known genome in an RNA virus. It is substantially larger than coronaviruses, another group of nidoviruses known for large genomes, which are typically in the 27-32kb range. PSCNV has an unusual genomic organization consisting of a single extremely large open reading frame (ORF) which encodes a polyprotein of 13,556 amino acids - the largest protein known to be encoded by an RNA virus. Bioinformatics analysis of the genome suggests it is organized similarly to canonical nidovirus genomes, in which ORF1a and ORF ...
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RNA Viruses
''Orthornavirae'' is a kingdom of viruses that have genomes made of ribonucleic acid (RNA), those genomes encoding an RNA-dependent RNA polymerase (RdRp). The RdRp is used to transcribe the viral RNA genome into messenger RNA (mRNA) and to replicate the genome. Viruses in this kingdom also share a number of characteristics involving evolution, including high rates of genetic mutations, recombinations, and reassortments. Viruses in ''Orthornavirae'' belong to the realm ''Riboviria''. They are descended from a common ancestor that may have been a non-viral molecule that encoded a reverse transcriptase instead of an RdRp for replication. The kingdom is subdivided into five phyla that separate member viruses based on their genome type, host range, and genetic similarity. Viruses with three genome types are included: positive-strand RNA viruses, negative-strand RNA viruses, and double-stranded RNA viruses. Many of the most widely known viral diseases are caused by RNA viruses in the ...
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Monotypic Taxon
In biology, a monotypic taxon is a taxonomic group (taxon) that contains only one immediately subordinate taxon. A monotypic species is one that does not include subspecies or smaller, infraspecific taxa. In the case of genera, the term "unispecific" or "monospecific" is sometimes preferred. In botanical nomenclature, a monotypic genus is a genus in the special case where a genus and a single species are simultaneously described. In contrast, an oligotypic taxon contains more than one but only a very few subordinate taxa. Examples Just as the term ''monotypic'' is used to describe a taxon including only one subdivision, the contained taxon can also be referred to as monotypic within the higher-level taxon, e.g. a genus monotypic within a family. Some examples of monotypic groups are: Plants * In the order Amborellales, there is only one family, Amborellaceae and there is only one genus, '' Amborella'', and in this genus there is only one species, namely ''Amborella trichopoda ...
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Virus Genera
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, ...
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