Mongolian Gerbil
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Mongolian Gerbil
The Mongolian gerbil or Mongolian jird (''Meriones unguiculatus'') is a small rodent belonging to the subfamily Gerbillinae. Their body size is typically , with a tail, and body weight , with adult males larger than females. The animal is used in science and kept as a small house pet. Their use in science dates back to the latter half of the 19th century, but they only started to be kept as pets in the English-speaking world after 1954, when they were brought to the United States. However, their use in scientific research has fallen out of favor. Habitat Mongolian gerbils inhabit grassland, shrubland and desert, including semidesert and steppes in China, Mongolia, and the Russian Federation. Soil on the steppes is sandy and is covered with grasses, herbs, and shrubs. The steppes have cool, dry winters and hot summers. The temperature can get up to , but the average temperature for most of the year is around . In the wild, these gerbils live in patriarchal groups generall ...
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Alphonse Milne-Edwards
Alphonse Milne-Edwards (Paris, 13 October 1835 – Paris, 21 April 1900) was a French mammalogist, ornithologist, and carcinologist. He was English in origin, the son of Henri Milne-Edwards and grandson of Bryan Edwards, a Jamaican planter who settled at Bruges (then in France). Milne-Edwards obtained a medical degree in 1859 and became assistant to his father at the ' in 1876. He became the director of the in 1891, devoting himself especially to fossil birds and deep-sea exploration. In 1881, he undertook a survey of the Gulf of Gascony with Léopold de Folin and worked aboard the ''Travailleur'' and the ''Talisman,'' researching the seas off the Canary Islands, the Cape Verde Islands, and the Azores. For this, he received a gold medal of the Royal Geographical Society. His major ornithological works include ' published in two parts in 1867 and 1872, ' 1866–1874 and ' 1868–1874. His study of fossils led to the discovery of tropical birds such as trogons and parrots from p ...
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National Museum Of Natural History (France)
The National Museum of Natural History is a natural history museum administered by the Smithsonian Institution, located on the National Mall in Washington, D.C., United States. It has free admission and is open 364 days a year. In 2021, with 7.1 million visitors, it was the list of most visited museums, eighteenth most visited museum in the world and the second most visited natural history museum in the world after the Natural History Museum, London, Natural History Museum in London."The World's most popular museums", CNN.com, 22 June 2017. Opened in 1910, the museum on the National Mall was one of the first Smithsonian buildings constructed exclusively to hold the national collections and research facilities. The main building has an overall area of with of exhibition and public space and houses over 1,000 employees. The museum's collections contain over 145 million specimens of plants, animals, fossils, minerals, rock (geology), rocks, meteorites, human remains, and human c ...
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Genotyping By Sequencing
In the field of DNA sequencing, genetic sequencing, genotyping by sequencing, also called GBS, is a method to discover Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP) in order to perform genotyping studies, such as genome-wide association studies (Genome-wide association study, GWAS). GBS uses restriction enzymes to reduce genome complexity and genotype multiple DNA samples. After digestion, Polymerase chain reaction, PCR is performed to increase fragments pool and then GBS libraries are sequenced using next generation sequencing technologies, usually resulting in about 100bp single-end reads. It is relatively inexpensive and has been used in plant breeding. Although GBS presents an approach similar to Restriction site associated DNA markers, restriction-site-associated DNA sequencing (RAD-seq) method, they differ in some substantial ways. Methods GBS is a robust, simple, and affordable procedure for SNP discovery and mapping. Overall, this approach reduces ge ...
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Genetic Marker
A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. It can be described as a variation (which may arise due to mutation or alteration in the genomic loci) that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change ( single nucleotide polymorphism, SNP), or a long one, like minisatellites. Background For many years, gene mapping was limited to identifying organisms by traditional phenotypes markers. This included genes that encoded easily observable characteristics such as blood types or seed shapes. The insufficient number of these types of characteristics in several organisms limited the mapping efforts that could be done. This prompted the development of gene markers which could identify genetic characteristics that are not readily observable in organisms (such as protein variation). Types Some commonly used types of genetic markers ...
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Diabetes Mellitus Type 2
Type 2 diabetes, formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, and unexplained weight loss. Symptoms may also include increased hunger, feeling tired, and sores that do not heal. Often symptoms come on slowly. Long-term complications from high blood sugar include heart disease, strokes, diabetic retinopathy which can result in blindness, kidney failure, and poor blood flow in the limbs which may lead to amputations. The sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon. Type 2 diabetes primarily occurs as a result of obesity and lack of exercise. Some people are genetically more at risk than others. Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primarily to type 1 diabetes and gestational diabetes. In type 1 diabet ...
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Fat Sand Rat
The fat sand rat (''Psammomys obesus'') is a terrestrial mammal from the gerbil subfamily that is mostly found in North Africa and the Middle East, ranging from Mauritania to the Arabian Peninsula. This species usually lives in sandy deserts, but may also be found in rocky terrain or saline marsh areas. Fat sand rats are very selective in their diet, only eating stems and leaves of plants from the family Amaranthaceae, more commonly known as the amaranth family. In captivity, fat sand rats can become obese and rapidly develop diabetes-like symptoms when fed the diet typically given to other rodents. ''P. obesus'' has an average lifespan of 14 months in the wild and 3–4 years in captivity. Ecology Activity patterns The fat sand rat is diurnal, but its activity on the surface fluctuates depending on the ambient temperature. Its period of activity is shortest in the summer, starting in the early morning and finishing an hour to several hours after. As the year progresses and t ...
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Seizure
An epileptic seizure, informally known as a seizure, is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain. Outward effects vary from uncontrolled shaking movements involving much of the body with loss of consciousness ( tonic-clonic seizure), to shaking movements involving only part of the body with variable levels of consciousness (focal seizure), to a subtle momentary loss of awareness ( absence seizure). Most of the time these episodes last less than two minutes and it takes some time to return to normal. Loss of bladder control may occur. Seizures may be provoked and unprovoked. Provoked seizures are due to a temporary event such as low blood sugar, alcohol withdrawal, abusing alcohol together with prescription medication, low blood sodium, fever, brain infection, or concussion. Unprovoked seizures occur without a known or fixable cause such that ongoing seizures are likely. Unprovoked seizures may be exacerbated by stress or sl ...
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Epilepsy
Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical activity in the brain. These episodes can result in physical injuries, either directly such as broken bones or through causing accidents. In epilepsy, seizures tend to recur and may have no immediate underlying cause. Isolated seizures that are provoked by a specific cause such as poisoning are not deemed to represent epilepsy. People with epilepsy may be treated differently in various areas of the world and experience varying degrees of social stigma due to the alarming nature of their symptoms. The underlying mechanism of epileptic seizures is excessive and abnormal neuronal activity in the cortex of the brain which can be observed in the electroencephalogram (EEG) of an individual. The reason this occurs in most cases of epilepsy is u ...
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Rattus Rattus Domesticus
The black rat (''Rattus rattus''), also known as the roof rat, ship rat, or house rat, is a common long-tailed rodent of the stereotypical rat genus ''Rattus'', in the subfamily Murinae. It likely originated in the Indian subcontinent, but is now found worldwide. The black rat is black to light brown in colour with a lighter underside. It is a generalist omnivore and a serious pest to farmers because it feeds on a wide range of agricultural crops. It is sometimes kept as a pet. In parts of India, it is considered sacred and respected in the Karni Mata Temple in Deshnoke. Taxonomy ''Mus rattus'' was the scientific name proposed by Carl Linnaeus in 1758 for the black rat. Three subspecies were once recognized, but today are considered invalid and are now known to be actually color morphs: *''Rattus rattus rattus'' – roof rat *''Rattus rattus alexandrinus'' – Alexandrine rat *''Rattus rattus frugivorus'' – fruit rat Characteristics A typical adult black rat is long, n ...
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Hearing Loss
Hearing loss is a partial or total inability to Hearing, hear. Hearing loss may be present at birth or acquired at any time afterwards. Hearing loss may occur in one or both ears. In children, hearing problems can affect the ability to Language acquisition, acquire spoken language, and in adults it can create difficulties with social interaction and at work. Hearing loss can be temporary or permanent. Presbycusis, Hearing loss related to age usually affects both ears and is due to cochlear hair cell loss. In some people, particularly older people, hearing loss can result in loneliness. Deafness, Deaf people usually have little to no hearing. Hearing loss may be caused by a number of factors, including: genetics, ageing, Noise-induced hearing loss, exposure to noise, some infections, birth complications, trauma to the ear, and certain medications or toxins. A common condition that results in hearing loss is chronic ear infections. Certain infections during pregnancy, such as cyt ...
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Charles River Laboratories
Charles River Laboratories International, Inc., is an American pharmaceutical company specializing in a variety of preclinical and clinical laboratory, gene therapy and cell therapy services for the Pharmaceutical, Medical device and Biotechnology industries. It also supplies assorted biomedical products, outsourcing services, and animals for research and development in the pharmaceutical industry (for example, contract research organization services) and offer support in the fields of basic research, drug discovery, safety and efficacy, clinical support, and manufacturing. The company's broad portfolio allowed them to support the development of approximately 85% of FDA-approved drugs in 2018. Its customers include leading pharmaceutical, biotechnology, agrochemical, government, and academic organization around the globe. The company has over 90 facilities, operates in 20 countries, and employs approximately 18,400 people worldwide. Charles River Laboratories is often criticize ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ...
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