Mollivirus
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Mollivirus
''Mollivirus sibericum'' is a giant virus discovered in 2015 by French researchers Chantal Abergel and Jean-Michel Claverie in a 30,000-year-old sample of Siberian permafrost, where the team had previously found the unrelated giant virus ''Pithovirus sibericum''. ''Mollivirus sibericum'' is a spherical DNA virus with a diameter of 500–600 nanometers (0.5–0.6 μm). ''Mollivirus sibericum'' is the fourth ancient virus that scientists have found frozen in permafrost since 2003. Description ''Mollivirus sibericum'' is an approximately spherical virion 0.6 μm in diameter. It encloses a 651 kb GC-rich genome encoding 523 proteins, of which 64% are ORFs.Strom, MarcuPrehistoric 'Frankenvirus' Mollivirus sibericum uncovered in Siberian permafrost''Sydney Morning Herald''. December 14, 2014 The host's ribosomal proteins are packaged in the virion. See also * Virus classification * Introduction to viruses * List of viruses This is an index of lists of virus ...
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Mollivirus Kamchatka
''Mollivirus sibericum'' is a giant virus discovered in 2015 by French researchers Chantal Abergel and Jean-Michel Claverie in a 30,000-year-old sample of Siberian permafrost, where the team had previously found the unrelated giant virus ''Pithovirus sibericum''. ''Mollivirus sibericum'' is a spherical DNA virus with a diameter of 500–600 nanometers (0.5–0.6 μm). ''Mollivirus sibericum'' is the fourth ancient virus that scientists have found frozen in permafrost since 2003. Description ''Mollivirus sibericum'' is an approximately spherical virion 0.6 μm in diameter. It encloses a 651 kb GC-rich genome encoding 523 proteins, of which 64% are ORFs.Strom, MarcuPrehistoric 'Frankenvirus' Mollivirus sibericum uncovered in Siberian permafrost''Sydney Morning Herald''. December 14, 2014 The host's ribosomal proteins are packaged in the virion. See also * Virus classification * Introduction to viruses * List of viruses This is an index of lists of virus ...
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Mollivirus Sibericum
''Mollivirus sibericum'' is a giant virus discovered in 2015 by French researchers Chantal Abergel and Jean-Michel Claverie in a 30,000-year-old sample of Siberian permafrost, where the team had previously found the unrelated giant virus ''Pithovirus sibericum''. ''Mollivirus sibericum'' is a spherical DNA virus with a diameter of 500–600 nanometers (0.5–0.6 μm). ''Mollivirus sibericum'' is the fourth ancient virus that scientists have found frozen in permafrost since 2003. Description ''Mollivirus sibericum'' is an approximately spherical virion 0.6 μm in diameter. It encloses a 651 kb GC-rich genome encoding 523 proteins, of which 64% are ORFs.Strom, MarcuPrehistoric 'Frankenvirus' Mollivirus sibericum uncovered in Siberian permafrost''Sydney Morning Herald''. December 14, 2014 The host's ribosomal proteins are packaged in the virion. See also * Virus classification * Introduction to viruses * List of viruses This is an index of lists of virus ...
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Permafrost
Permafrost is ground that continuously remains below 0 °C (32 °F) for two or more years, located on land or under the ocean. Most common in the Northern Hemisphere, around 15% of the Northern Hemisphere or 11% of the global surface is underlain by permafrost, with the total area of around 18 million km2. This includes substantial areas of Alaska, Greenland, Canada and Siberia. It can also be located on mountaintops in the Southern Hemisphere and beneath ice-free areas in the Antarctic. Permafrost does not have to be the first layer that is on the ground. It can be from an inch to several miles deep under the Earth's surface. It frequently occurs in ground ice, but it can also be present in non-porous bedrock. Permafrost is formed from ice holding various types of soil, sand, and rock in combination. Permafrost contains large amounts of biomass and decomposed biomass that has been stored as methane and carbon dioxide, making tundra soil a carbon sink. As global war ...
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Nucleocytoplasmic Large DNA Viruses
''Nucleocytoviricota'' is a phylum of viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with the suffix - for virus phylum. These viruses are referred to as nucleocytoplasmic because they are often able to replicate in both the host's cell nucleus and cytoplasm. The phylum is notable for containing the giant viruses. There are nine families of NCLDVs that all share certain genomic and structural characteristics; however, it is uncertain whether the similarities of the different families of this group have a common viral ancestor. One feature of this group is a large genome and the presence of many genes involved in DNA repair, DNA replication, transcription, and translation. Typically, viruses with smaller genomes do not contain genes for these processes. Most of the viruses in this family also replicate in both the host's nucleus and cytoplasm, thus the name nucleocytoplasmic. Th ...
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Introduction To Viruses
A virus is a tiny infectious agent that reproduces inside the cells of living hosts. When infected, the host cell is forced to rapidly produce thousands of identical copies of the original virus. Unlike most living things, viruses do not have cells that divide; new viruses assemble in the infected host cell. But unlike simpler infectious agents like prions, they contain genes, which allow them to mutate and evolve. Over 4,800 species of viruses have been described in detail out of the millions in the environment. Their origin is unclear: some may have evolved from plasmids—pieces of DNA that can move between cells—while others may have evolved from bacteria. Viruses are made of either two or three parts. All include genes. These genes contain the encoded biological information of the virus and are built from either DNA or RNA. All viruses are also covered with a protein coat to protect the genes. Some viruses may also have an envelope of fat-like substance that ...
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Giant Virus
A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. All known giant viruses belong to the phylum ''Nucleocytoviricota''. Description While the exact criteria as defined in the scientific literature vary, giant viruses are generally described as viruses having large, pseudo- icosahedral capsids (200 to 400 nanometers in diameter) that may be surrounded by a thick (approximately 100 nm) layer of filamentous protein fibers. The viruses have large, double-stranded DNA genomes (300 to >1000 kilobasepairs) that encode a large contingent of genes (of the order of 1000 genes). The best characterized giant viruses are the phylogenetically related mimivirus and megavirus, which belong to the family ''Mimiviridae'' (aka ''Megaviridae''), and are distinguished by their large capsid diameters. Giant viruses from the deep ocean, terrestrial sources, and human patients contain genes encoding Cytochrome P450, cytochrome P45 ...
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France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ...
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Pithovirus Sibericum
''Pithovirus'', first described in a 2014 paper, is a genus of giant virus known from two species, ''Pithovirus sibericum'', which infects amoebas and ''Pithovirus massiliensis''. It is a base pair, double-stranded DNA virus, and is a member of the nucleocytoplasmic large DNA viruses clade. The 2014 discovery was made when a viable specimen was found in a 30,000-year-old ice core harvested from permafrost in Siberia, Russia. Description The genus name ''Pithovirus'', a reference to large storage containers of ancient Greece known as pithos, pithoi, was chosen to describe the new species. A specimen of ''Pithovirus'' measures approximately 1.5 μm (1500 nanometre, nm) in length and 0.5 μm (500 nm) in diameter, making it the largest virus yet found. It is 50% larger in size than the ''Pandoraviridae'', the previous largest-known viruses, and is larger than ''Ostreococcus'', the smallest eukaryotic cell, although ''Pandoravirus'' has the largest viral genome, contai ...
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DNA Virus
A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong to two realms: ''Duplodnaviria'' and ''Varidnaviria'', and ssDNA viruses are almost exclusively assigned to the realm ''Monodnaviria'', which also includes some dsDNA viruses. Additionally, many DNA viruses are unassigned to higher taxa. Reverse transcribing viruses, which have a DNA genome that is replicated through an RNA intermediate by a reverse transcriptase, are classified into the kingdom '' Pararnavirae'' in the realm '' Riboviria''. DNA viruses are ubiquitous worldwide, especially in marine environments where they form an important part of marine ecosystems, and infect both prokaryotes and eukaryotes. The ...
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GC-content
In molecular biology and genetics, GC-content (or guanine-cytosine content) is the percentage of nitrogenous bases in a DNA or RNA molecule that are either guanine (G) or cytosine (C). This measure indicates the proportion of G and C bases out of an implied four total bases, also including adenine and thymine in DNA and adenine and uracil in RNA. GC-content may be given for a certain fragment of DNA or RNA or for an entire genome. When it refers to a fragment, it may denote the GC-content of an individual gene or section of a gene (domain), a group of genes or gene clusters, a non-coding region, or a synthetic oligonucleotide such as a primer. Structure Qualitatively, guanine (G) and cytosine (C) undergo a specific hydrogen bonding with each other, whereas adenine (A) bonds specifically with thymine (T) in DNA and with uracil (U) in RNA. Quantitatively, each GC base pair is held together by three hydrogen bonds, while AT and AU base pairs are held together by two hydrogen bonds. ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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