Miniature American Shepherd
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Miniature American Shepherd
The Miniature American Shepherd, frequently abbreviated MAS, is a small herding dog breed. The MAS is highly intelligent and biddable. The breed is often trained for dog sports such as herding, agility, obedience, canine freestyle, flyball, and others. The Miniature American Shepherd was recognised by the American Kennel Club (AKC) in 2015 and is the club's 186th breed. In September 2019, the Fédération Cynologique Internationale (FCI) officially accepted the breed. History The MAS was bred first in the United States as a small herding and working dog. The Miniature American Shepherd (at that time still the Miniature Australian Shepherd) was first developed in the late 1960s by breeding what was thought to be small Australian Shepherds, and by the mid-1970s the breed had reached its current desired size. In many areas and kennel clubs the Miniature American Shepherd is still used as a working breed in competitions. The predecessor to MASCUSA was the North American Miniatur ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ...
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Cataract
A cataract is a cloudy area in the lens of the eye that leads to a decrease in vision. Cataracts often develop slowly and can affect one or both eyes. Symptoms may include faded colors, blurry or double vision, halos around light, trouble with bright lights, and trouble seeing at night. This may result in trouble driving, reading, or recognizing faces. Poor vision caused by cataracts may also result in an increased risk of falling and depression. Cataracts cause 51% of all cases of blindness and 33% of visual impairment worldwide. Cataracts are most commonly due to aging but may also occur due to trauma or radiation exposure, be present from birth, or occur following eye surgery for other problems. Risk factors include diabetes, longstanding use of corticosteroid medication, smoking tobacco, prolonged exposure to sunlight, and alcohol. The underlying mechanism involves accumulation of clumps of protein or yellow-brown pigment in the lens that reduces transmission of li ...
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FCI Breeds
FCI may refer to: Companies and organizations * Falling Creek Ironworks, the first iron production facility in North America * Family Carers Ireland, Irish lobbying group * Federal Correctional Institution, part of the United States Bureau of Prisons * Fédération Cynologique Internationale, the World Canine Federation * Fertilizer Corporation of India, an Indian government-owned corporation * Fluid Components International, an American manufacturing company * Food Corporation of India, an Indian government-owned corporation * Francis Crick Institute, a British biomedical research centre * Fujisankei Communications International, an American media company Sports * F.C. Indiana, an American soccer team * FC Ingolstadt 04, a German football club * FCI Tallinn, an Estonian football club * Food Corporation of India F.C., an Indian football club * Italian Cycling Federation (Italian: ) Standards and measures * Facility condition index, in building management * fCi, the symbol ...
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List Of Dog Breeds
This list of dog breeds includes both Neontology#Extant taxa versus extinct taxa, extant and extinct dog breeds, Designer breed, varieties, landraces, and dog types. A research article on genomics, dog genomics published in Science/AAAS defines modern dog breeds as "a recent invention defined by conformation to a physical ideal and purity of lineage". Extant breeds, landraces, varieties and types Note: not all dogs listed below are recognized breeds by an official breed registry that can certify the dog is a purebred, including The Kennel Club (TKC - 1873), the oldest and first official dog breed registry in the world, located in the United Kingdom, and the three oldest breed registries in North America, and largest in the world, including the American Kennel Club (AKC - 1884), United Kennel Club (UKC - 1898), and Canadian Kennel Club (CKC - 1888). A–C D–K L–R S–Z Extinct breeds, landraces, varieties and types Notes References Citations Bib ...
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Dogs
The dog (''Canis familiaris'' or ''Canis lupus familiaris'') is a domesticated descendant of the wolf. Also called the domestic dog, it is derived from the extinct Pleistocene wolf, and the modern wolf is the dog's nearest living relative. Dogs were the first species to be domesticated by hunter-gatherers over 15,000 years ago before the development of agriculture. Due to their long association with humans, dogs have expanded to a large number of domestic individuals and gained the ability to thrive on a starch-rich diet that would be inadequate for other canids. The dog has been selectively bred over millennia for various behaviors, sensory capabilities, and physical attributes. Dog breeds vary widely in shape, size, and color. They perform many roles for humans, such as hunting, herding, pulling loads, protection, assisting police and the military, companionship, therapy, and aiding disabled people. Over the millennia, dogs became uniquely adapted to human behavior, and ...
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Canine Degenerative Myelopathy
Canine degenerative myelopathy, also known as chronic degenerative radiculomyelopathy, is an incurable, progressive disease of the canine spinal cord that is similar in many ways to amyotrophic lateral sclerosis (ALS). Onset is typically after the age of 7 years and it is seen most frequently in the German shepherd dog, Pembroke Welsh corgi, and boxer dog, though the disorder is strongly associated with a gene mutation in ''SOD1'' that has been found in 43 breeds as of 2008, including the wire fox terrier, Chesapeake Bay retriever, Rhodesian ridgeback, and Cardigan Welsh corgi. Progressive weakness and incoordination of the rear limbs are often the first signs seen in affected dogs, with progression over time to complete paralysis. Myelin is an insulating sheath around neurons in the spinal cord. One proposed cause of degenerative myelopathy is that the immune system attacks this sheath, breaking it down. This results in a loss of communication between nerves in lower body of th ...
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Hip Dysplasia (canine)
In dogs, hip dysplasia is an abnormal formation of the hip socket that, in its more severe form, can eventually cause lameness and arthritis of the joints. It is a genetic (polygenic) trait that is affected by environmental factors. It is common in many dog breeds, particularly the larger breeds, and is the most common single cause of arthritis of the hips. During growth, both the ball (the head of the femur, or thighbone) and the socket in the pelvis (acetabulum) must grow at equal rates. In hip dysplasia, this uniform growth during puppyhood does not occur. The result is laxity (looseness) of the joint, followed by degenerative joint disease (DJD) or osteoarthritis (OA), which is the body's attempt to stabilize the loose hip joint. Overview Normal hip anatomy In the normal anatomy of the hip joint, the almost spherical end of the femur head (the caput, or caput ossis femoris) fits into the acetabulum (a concave socket located in the pelvis). The bony surfaces of the femur he ...
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Multi-drug Resistance Gene
P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi, and bacteria, and it likely evolved as a defense mechanism against harmful substances. P-gp is extensively distributed and expressed in the intestinal epithelium where it pumps xenobiotics (such as toxins or drugs) back into the intestinal lumen, in liver cells where it pumps them into bile ducts, in the cells of the proximal tubule of the kidney where it pumps them into urinary filtrate (in the proximal tubule), and in the capillary endothelial cells composing the blood–brain barrier and blood–testis barrier, where it pumps them back into the capill ...
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Microphthalmia
Microphthalmia (Greek: grc, μικρός, mikros, small, label=none, grc, ὀφθαλμός, ophthalmos, eye, label=none, also referred as microphthalmos, is a developmental disorder of the eye in which one (unilateral microphthalmia) or both (bilateral microphthalmia) eyes are abnormally small and have anatomic malformations. Microphthalmia is a distinct condition from anophthalmia and nanophthalmia. Although sometimes referred to as 'simple microphthalmia', nanophthalmia is a condition in which the size of the eye is small but no anatomical alterations are present. Presentation Microphthalmia is a congenital disorder in which the globe of the eye is unusually small and structurally disorganized. While the axis of an adult human eye has an average length of about , a diagnosis of microphthalmia generally corresponds to an axial length below in adults. Additionally, the diameter of the cornea is about in affected newborns and in adults with the condition. The presence of a sm ...
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Coloboma
A coloboma (from the Greek , meaning defect) is a hole in one of the structures of the eye, such as the iris, retina, choroid, or optic disc. The hole is present from birth and can be caused when a gap called the choroid fissure, which is present during early stages of prenatal development, fails to close up completely before a child is born. Ocular coloboma is relatively uncommon, affecting less than one in every 10,000 births. The classical description in medical literature is of a keyhole-shaped defect. A coloboma can occur in one eye (unilateral) or both eyes (bilateral). Most cases of coloboma affect only the iris. The level of vision impairment of those with a coloboma can range from having no vision problems to being able to see only light or dark, depending on the position and extent of the coloboma (or colobomata if more than one is present). Signs and symptoms Visual effects may be mild to more severe depending on the size and location of the coloboma. If, for exam ...
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Progressive Retinal Atrophy
Progressive retinal atrophy (PRA) is a group of genetic diseases seen in certain breeds of dogs and, more rarely, cats. Similar to retinitis pigmentosa in humans, it is characterized by the bilateral degeneration of the retina, causing progressive vision loss culminating in blindness. The condition in nearly all breeds is inherited as an autosomal recessive trait, with the exception of the Siberian Husky (inherited as an X chromosome linked trait) and the Bullmastiff (inherited as an autosomal dominant trait). There is no treatment. Types of PRA In general, PRAs are characterised by initial loss of rod photoreceptor cell function followed by that of the cones and for this reason night blindness is the first significant clinical sign for most dogs affected with PRA. As other retinal disorders, PRA can be divided into either dysplastic disease, where the cells develop abnormally, and degenerative, where the cells develop normally but then degenerate during the dog's lifetime. Ge ...
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American Kennel Club
The American Kennel Club (AKC) is a registry of purebred dog pedigrees in the United States. In addition to maintaining its pedigree registry, this kennel club also promotes and sanctions events for purebred dogs, including the Westminster Kennel Club Dog Show, an annual event which predates the official forming of the AKC, the National Dog Show and the AKC National Championship. The AKC is a non-member partner with the Fédération Cynologique Internationale. The AKC recognizes 200 dog breeds, as of 2022. History In the early 1800s, the English became concerned with the beauty of dogs as well as their function. This fad spread to North America, and in 1877, the Westminster Kennel Club Dog Show began. Soon after, the need for a regulating body became obvious. The National American Kennel Club, which had been founded in 1876, began to publish and make publicly available its studbook in 1879. This organization, however, had a more vested interest in field trials than in conformat ...
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