Medical Uses Of Silver
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Medical Uses Of Silver
The medical uses of silver include its use in wound dressings, creams, and as an antibiotic coating on medical devices. Wound dressings containing silver sulfadiazine or silver nanomaterials may be used to treat external infections. The limited evidence available shows that silver coatings on endotracheal breathing tubes may reduce the incidence of ventilator-associated pneumonia. There is tentative evidence that using silver-alloy indwelling catheters for short-term catheterizing will reduce the risk of catheter-acquired urinary tract infections. Silver generally has low toxicity, and minimal risk is expected when silver is used in approved medical applications. Alternative medicine products such as colloidal silver are not safe or effective. Mechanism of action Silver and most silver compounds have an oligodynamic effect and are toxic for bacteria, algae, and fungi ''in vitro''. The antibacterial action of silver is dependent on the silver ion. The effectiveness of silver c ...
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Silver
Silver is a chemical element with the symbol Ag (from the Latin ', derived from the Proto-Indo-European ''h₂erǵ'': "shiny" or "white") and atomic number 47. A soft, white, lustrous transition metal, it exhibits the highest electrical conductivity, thermal conductivity, and reflectivity of any metal. The metal is found in the Earth's crust in the pure, free elemental form ("native silver"), as an alloy with gold and other metals, and in minerals such as argentite and chlorargyrite. Most silver is produced as a byproduct of copper, gold, lead, and zinc refining. Silver has long been valued as a precious metal. Silver metal is used in many bullion coins, sometimes alongside gold: while it is more abundant than gold, it is much less abundant as a native metal. Its purity is typically measured on a per-mille basis; a 94%-pure alloy is described as "0.940 fine". As one of the seven metals of antiquity, silver has had an enduring role in most human cultures. Oth ...
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Ventilator-associated Pneumonia
Ventilator-associated pneumonia (VAP) is a type of lung infection that occurs in people who are on mechanical ventilation breathing machines in hospitals. As such, VAP typically affects critically ill persons that are in an intensive care unit (ICU) and have been on a mechanical ventilator for at least 48 hours.Cooper A.S. Oral hygiene care to prevent ventilator-associated pneumonia in critically ill patients. ''Crit. Care Nurs..'' 2021;41(4):80-82. doi:10.4037/ccn2021314 VAP is a major source of increased illness and death. Persons with VAP have increased lengths of ICU hospitalization and have up to a 20–30% death rate. The diagnosis of VAP varies among hospitals and providers but usually requires a new infiltrate on chest x-ray plus two or more other factors. These factors include temperatures of >38 °C or 12 × 109/ml, purulent secretions from the airways in the lung, and/or reduction in gas exchange. A different less studied infection found in mechanically ventilat ...
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Silver Acetate
Silver acetate is an coordination compound with the empirical formula CH3CO2Ag (or AgC2H3O2). A photosensitive, white, crystalline solid, it is a useful reagent in the laboratory as a source of silver ions lacking an oxidizing anion. Synthesis and structure Silver acetate can be synthesized by the reaction of acetic acid and silver carbonate. :2 CH3CO2H + Ag2CO3 → 2 AgO2CCH3 + H2O + CO2 Solid silver acetate precipitates upon concentration of solutions of silver nitrate and sodium acetate. The structure of silver acetate consists of 8-membered Ag2O4C2 rings formed by a pair of acetate ligands bridging a pair of silver centres. Reactions Silver acetate finds use in certain transformations in organic synthesis. Sulfenamide synthesis Silver acetate is used to prepare sulfenamides from disulfides and secondary amines: : R2NH + AgOAc + (RS)2 → R2NSR + AgSR + HOAc Hydrogenation A solution of silver acetate in pyridine absorbs hydrogen, producing metallic silver: :2 CH3CO2Ag + ...
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Amalgam (dentistry)
Dental amalgam is a liquid mercury and metal alloy mixture used in dentistry to fill cavities caused by tooth decay. Low-copper amalgam commonly consists of mercury (50%), silver (~22–32%), tin (~14%), zinc (~8%) and other trace metals. Dental amalgams were first documented in a Tang Dynasty medical text written by Su Gong (苏恭) in 659, and appeared in Germany in 1528. In the 1800s, amalgam became the dental restorative material of choice due to its low cost, ease of application, strength, and durability. In July 2018 the EU prohibited amalgam for dental treatment of children under 15 years and of pregnant or breastfeeding women. History of use There are, according to Geir Bjørklund, indications that dental amalgam was used in the first part of the Tang Dynasty in China (AD 618–907), and in Germany by Strockerus in about 1528. Evidence of a dental amalgam first appears in the Tang Dynasty medical text ''Xinxiu bencao''《新修本草》 written by Su Gong (苏 ...
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Silver Diamine Fluoride
Silver diammine fluoride (SDF), also known as silver diamine fluoride in most of the dental literature, (although this is a chemical misnomer) is a topical medication used to treat and prevent dental caries (tooth decay) and relieve dentinal hypersensitivity. It is a colorless (most products) or blue-tinted (Advantage Arrest), odourless liquid composed of silver, ammonium and fluoride ions at a pH of 10.4 (most products) or 13 (Riva Star). Ammonia compounds reduce the oxidative potential of SDF, increase its stability and helps to maintain a constant concentration over a period of time, rendering it safe for use in the mouth. Silver and fluoride ions possess antimicrobial properties and are used in the remineralization of enamel and dentin on teeth for preventing and arresting dental caries. SDF is also known as diammine silver fluoride, silver fluoride, and silver ammonium fluoride. It is frequently spelled "silver diamine fluoride" (with one ''m''); however, this is a misnome ...
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Cauterization
Cauterization (or cauterisation, or cautery) is a medical practice or technique of burning a part of a body to remove or close off a part of it. It destroys some tissue in an attempt to mitigate bleeding and damage, remove an undesired growth, or minimize other potential medical harm, such as infections when antibiotics are unavailable. The practice was once widespread for treatment of wounds. Its utility before the advent of antibiotics was said to be effective at more than one level: *To prevent exsanguination *To close amputations Cautery was historically believed to prevent infection, but current research shows that cautery actually increases the risk for infection by causing more tissue damage and providing a more hospitable environment for bacterial growth. Actual cautery refers to the metal device, generally heated to a dull red glow, that a physician applies to produce blisters, to stop bleeding of a blood vessel, and for other similar purposes., page 16. The main f ...
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Conjunctivitis
Conjunctivitis, also known as pink eye, is inflammation of the outermost layer of the white part of the eye and the inner surface of the eyelid. It makes the eye appear pink or reddish. Pain, burning, scratchiness, or itchiness may occur. The affected eye may have increased tears or be "stuck shut" in the morning. Swelling of the white part of the eye may also occur. Itching is more common in cases due to allergies. Conjunctivitis can affect one or both eyes. The most common infectious causes are viral followed by bacterial. The viral infection may occur along with other symptoms of a common cold. Both viral and bacterial cases are easily spread between people. Allergies to pollen or animal hair are also a common cause. Diagnosis is often based on signs and symptoms. Occasionally, a sample of the discharge is sent for culture. Prevention is partly by handwashing. Treatment depends on the underlying cause. In the majority of viral cases, there is no specific treatment. Mo ...
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Silver Proteinate
Silver proteinate (brand name: Protargol) is used in electron microscopy with periodic acid and thiocarbohydrazide or thiosemicarbohydrazide as a positive stain for carbohydrates such as glycogen. It can also be used for light microscopy to stain nerve tissue. It is normally available as 8% silver in combination with albumin. Because of its bactericidal properties it was used to treat gonorrhea before the discovery of antibiotics. The inventor of the first silver protein formulation was Arthur Eichengrün, a German chemist working for Bayer. It was introduced for therapeutic use in 1897.State Medical Examining and Licensing Boards A Handbook of Useful Drugs: Protargol' 1913 Press Of The American Medical Association (''hosted on: chestofbooks.com'') See also * Medical uses of silver The medical uses of silver include its use in wound dressings, creams, and as an antibiotic coating on medical devices. Wound dressings containing silver sulfadiazine or silver nanomaterials may b ...
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Silver Nitrate
Silver nitrate is an inorganic compound with chemical formula . It is a versatile precursor to many other silver compounds, such as those used in photography. It is far less sensitive to light than the halides. It was once called ''lunar caustic'' because silver was called ''luna'' by ancient alchemists who associated silver with the moon. In solid silver nitrate, the silver ions are three- coordinated in a trigonal planar arrangement. Synthesis and structure Albertus Magnus, in the 13th century, documented the ability of nitric acid to separate gold and silver by dissolving the silver. Indeed silver nitrate can be prepared by dissolving silver in nitric acid followed by evaporation of the solution. The stoichiometry of the reaction depends upon the concentration of nitric acid used. :3 Ag + 4 HNO3 (cold and diluted) → 3 AgNO3 + 2 H2O + NO :Ag + 2 HNO3 (hot and concentrated) → AgNO3 + H2O + NO2 The structure of silver nitrate has been examined by X-ray crystallography ...
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X-ray
An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10  picometers to 10  nanometers, corresponding to frequencies in the range 30  petahertz to 30  exahertz ( to ) and energies in the range 145  eV to 124 keV. X-ray wavelengths are shorter than those of UV rays and typically longer than those of gamma rays. In many languages, X-radiation is referred to as Röntgen radiation, after the German scientist Wilhelm Conrad Röntgen, who discovered it on November 8, 1895. He named it ''X-radiation'' to signify an unknown type of radiation.Novelline, Robert (1997). ''Squire's Fundamentals of Radiology''. Harvard University Press. 5th edition. . Spellings of ''X-ray(s)'' in English include the variants ''x-ray(s)'', ''xray(s)'', and ''X ray(s)''. The most familiar use of X-rays is checking for fractures (broken bones), but X-rays are also used in other ways. ...
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Acanthamoebidae
Acanthamoebidae is a family of single-celled eukaryotes within the group Amoebozoa. It gets its name from ''Acanthamoeba'', its best-known member. However, it also includes other species, such as '' Comandonia operculata'' and '' Protacanthamoeba bohemica''. Many kinds of Acanthamoebidae are highly prevalent in the soil and water of a variety of environments. They are similar to Hartmannella, but have differently structured pseudopodia, in regard to the actin microfilaments that comprise them. Its most prominent member, ''Acanthamoeba'', can be potentially pathogenic to humans and animals. It has been described as having a common origin with the Entamoebidae and Dictyosteliida. Structure Members of Acanthamoebidae have a specific form of pseudopodia, dubbed acanthopodia. These acanthopodia are continuously formed and reabsorbed, protrude from every area of the cell’s surface, and are usually, short and fine. An exception would be ''A. astronyxis'' and ''A. comandoni'', in ...
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Central Venous Catheters
A central venous catheter (CVC), also known as a central line(c-line), central venous line, or central venous access catheter, is a catheter placed into a large vein. It is a form of venous access. Placement of larger catheters in more centrally located veins is often needed in critically ill patients, or in those requiring prolonged intravenous therapies, for more reliable vascular access. These catheters are commonly placed in veins in the neck (internal jugular vein), chest ( subclavian vein or axillary vein), groin (femoral vein), or through veins in the arms (also known as a PICC line, or peripherally inserted central catheters). Central lines are used to administer medication or fluids that are unable to be taken by mouth or would harm a smaller peripheral vein, obtain blood tests (specifically the "central venous oxygen saturation"), administer fluid or blood products for large volume resuscitation, and measure central venous pressure. The catheters used are commonly ...
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